@article { author = {POUR eSLAMI, H.R and Moshtaghi, GH.R and Hori, A and SHarifi, M and Ziaaddini, H}, title = {Comparison of Salivary Secretory IgA in Caries-free Children and Children with Severe Early Childhood Caries}, journal = {Journal of Kerman University of Medical Sciences}, volume = {17}, number = {1}, pages = {83-88}, year = {2010}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {Background & Aims: Sever early childhood caries (SECC) is a multifactor common disease that unfortunately there have been a lot of unknown points about it. This study was performed to compare the levels of total S-IgA in children with and without SECC. Methods: In this cross-sectional study 44 children aged 6-24 months were divided into two groups of with SECC (n=20) and without SECC (n=24). The two groups were compared for the concentration of S-IgA assessed with Nephlometric method. The obtained data were analyzed by using t-test and through SPSS 15 software. Results: Mean saliva concentration of S-IgA in children with SECC (18.30 mg/dl) was higher than that in children without SECC (9.46 mg/dl) and this difference was statistically Significant (P<0.05). Conclusion: According to this study, the hypothesis of lower levels of S-IgA in children with SECC might be rejected.}, keywords = {immunoglobulins,Saliva,Dental Caries}, url = {https://jkmu.kmu.ac.ir/article_16676.html}, eprint = {https://jkmu.kmu.ac.ir/article_16676_88eca6dd0fd87ba53d371f23f9af8ba2.pdf} }