eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
60
67
33785
The Antiiflammtory Activity of calcium-channel antagonists on chronic inflammation in rat
M Khansari
1
M.A Sajadi
2
M Zienalizadeh
3
M Moosavi
4
Associate professor
Assistant professor
...
...
calcium mobilization is known to be an important factor in the activation of cells involved in inflammation,so,calcium-channel antagonists are be expected ti exhibit antiinflammatory activity.in the present study,we evaluateted the antiinflammatory effects of two calcium channel blockers,verapamil and nifedipine on adjuvant induced chronic in flammation in rat paw.sixty adult male rats were divided into 5 groups.chronic paw edema was induced by intraplantar injection of 0.1 ml of freunds complete adjuvant(FCA).inflammatory edema measured in 0,1,2,3,4,5,6,7,14,21, and 28 days after adjuvant inoculation.verapamil(25mg/kg),nifedipine(100mg/kg),ibuprofen(12mg/kg)
with DMSO(dimethyl sulphoxide) were given to animals daily through intragastric device from day 7 after adjuvant injection.assessment of edema proformed by calculation of volume changes and by extravasation of Evans blue (E.B.) in the test groups compared to the control.FCA caused a remarkable incerase in paw edema (0.8+_0.05 ml)after 28 days.verapamil significantly redused the paw edema(62.5%) at day 28.A market inhibition was indused by mifedipine(50%) and ibuprofen(60%).No significant differences were found between inhibitory effects of ibuprofen and other drugs.Non of the drugs have any effect on the extravasation of E.B. these data suggest that calcium channel blockers,inhibit adjuvant induced chronic inflammation in rats and these effects are comparable to that of ibuprofen.
https://jkmu.kmu.ac.ir/article_33785_cf752df390334ec1b2bde34e5c8ae2cb.pdf
calcium-channel antagonists
Verapamil
nifedipine
chronic inflammation
adjuvant
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
68
73
33786
comparison of apical leakage in leteral condensatsion with and without tug-back with Two types of root canal sealers
M Parirokh
1
M.K Hamedzadeh
2
F Hossien-Nakhaei
3
M Tarashi
4
Associate profrssor
Assistant professor
...
...
in order to deermine the effect of root canal cealer on microleakage of obturated root canal by lateral condensation technique(LCT) with and without tug-back(TB).seventy exteracted single root canal teeth were examined.after preparation of root canal with step-back technique,teeth were divided to six groups as follows:5 teeth as positive control group that obturated by LCT with gutta-perch ithout sealer.5 teeth as negative control group in which entire root surfaces and apical foramen coated with nail varnish,and four experimental groups(each group consisted of 15 teeth).hroup I ZOE with TB.group II ZOE without TB.group III roth sealer with TB. and group IV roth sealer without TB.then the teeth were immerssed in pelikan ink for 72 hours and weparated in two peices through vertical long axis.stereomicroscope observation showed that tb groups (I &III) have statistically less microleakage then non TB groups (II&IV) (P<0.0001).there was no significant diffeernces between two TB groups.results also showed no relationship between root canal sealer and apical leakage with and without TB in both type of sealer.
https://jkmu.kmu.ac.ir/article_33786_bfb1f299d8b34b2c57f03a982a3361dd.pdf
lateral condensation
Tug-bac
sealer
canal obturation
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
74
78
33787
study of short-term complications and advantages of peritoneal closure or non-closure at cesaeran
N Eftekhari
1
M Forotan
2
Assistant professor
...
In the randomized clinical trial 200 pregnant women reffred to Niknafs maternity center from November 1997 to May 1998 were divided into two groups and underwent cesarean section.in the first group (control) the parietal and visceral peritoneum were approximated with delayed absorbable material whereas in the second group (case) the parietal and visceral peritoneum were left open.the mean age of the patients was 27.5+_5.5. there was no significant difference between the two groups with regard to the age,parity,gravidity,gestational age,indication for surgery, the type of anesthesia,incision type,administration of antibiotice and accompanied tubectomy(p>0.05).the mean time for the procedure was 36+_5.7 and 42+_7.9 minutes in the case and control group,respectively.the severity of postoperative pain was lower in the case group as compared eith the control group.there were significant differences regarding the postoperative pain,the time of procedure and the mean time for the retun of bowel sound movements between the two groups.It is concluded that non closure of the peritioneum is associated with lower rate of morbidity and it seems to be more benefacial.
https://jkmu.kmu.ac.ir/article_33787_f79470ddae3ae8046fd5466c287a9ff8.pdf
cesarean
peritoneal closure
non closure of peritoneum
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
79
85
33788
The reletionship between depression and disability in patient with rheumatoid arthritis in Kerman
J Atapour
1
M.R Shakibi
2
GH Rajabizadeh
3
M Saroteh-Rigi
4
Assistant professor
Assistant professor
Assistant professor
...
Depression is an important problem among persons with rheumatiod arthritis(RA).It appears to be more prevalent among persons with RA than in the general population.Moreover studies of individuals with RAhave demonstrated cross-sectional relationships between depression and disabiltiy of RA patients.to examine the relationship between disability and depression in RA patients in Kerman a prospective cross sectional study with concecutive sampling in private rheumatology clinic was designed.logestic regression models showed that depression is the risk factor for disability(Odds ratio=OR=6.8P=0.009) and for the depression(OR=7.2 P=0.007).the findings determind that disability and depression are interrelated,each of them is a risk foctor for other.
https://jkmu.kmu.ac.ir/article_33788_7003e54409f678a8bedf7696e6dc662b.pdf
depression
Disability
Rheumatoid arthritis(RA)
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
86
92
33789
Survey of knowledge,Attitude and practice among general practitioners and internists on helicobacter pylori in peptic ulcer disease in Kerman
s Darvish-Moghadam
1
M.J Zahedi
2
Assistent professor
Assistent professor
physicians awareness about Helicobacter pylori association with peptic ulcer disease (PUD)has changed the natural course of this prolonged disease.Eradication of this organism has declined the incidence of complications and recurrence of PUD significantly in recent years.the aim of this cross sectional study was to evaluate the level of knowledge,attitude and practice (KAP) of general practitioners(GPs) and internal medicine specialists (IMS) about H.pylori,its relationship to peptic ulcer and the management.the study was contucted on 206 practicing clinicians (179 GP,27 IMS) by using a self administered questionaire.the data were analyzed with following results.the mean age for GPs was 35.7+_10.3 years and that of IMSs was 42.7+_8.5. correct rate in KAP domains for GPs was 45.8% ,25.4%,34.6% respectively as it was 81.5%,70% and 74% for IMS.regarding the causes of PUD,49.2% of GPs and 81.5% of IMS believed in more than 50% role for H.pylori.40.2% of GPs and 81.5% of IMS pointed at the nesessity for treatment of H.pylori infection,however 77.8% of IMS and 8.9% of GPs treated the cases by a standard eradication therapy.53.7% of GPs reffered the paients to specialists.from a maximum of 40 scores,the average sore for GPs was 16.4+_2 whereeas for IMS it was 33.8+_1.9. by using pearson correlation there was a direct but weak correlation between knowledge-attitud (r=0.20) and knowledge-practice(r=0.12) for GPs.these figures for IMS were r=0.35 and r=0.46 respectively.the results of this study indicate that appropriate management of H.pylori in PUD by physician is inadequate and it needs educational attention especially for GPs.
https://jkmu.kmu.ac.ir/article_33789_c707f1d66e3be472d0366477687d08ba.pdf
peptic ulcer disease
Helicobacter pylori
general practitioner
internist
knowledge
Attitude
Practice
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
93
101
33790
Using the PRECEDE model for causal analysis of mothers preventive behaviors in Iron deficiency anemia of children aged 1-5 years old
Z Jalili
1
S Faghihzadeh
2
A.R Heidarnia
3
M.M Hazavei
4
S.M Sadat-Hashemi
5
Assistant professor
Assistant professor
Associate professor
Assistant professor
phd student
the requirement of iron insreased in growing children due to accelerating of growth.However nutritional iron intake and capacity to adopt iron deficiency are limited.it is not surprising then,that iron deficiency is most common in infants and children.therefore iron deficiency aneamia(IDA) is a topic of importance,not only for the management of individual patients but also for necessary public health measures to improve the diet of the population as a whole.mothers should especially be educated to improve better diet health behaviors for their children.the peresent study was carried out to survey 160 mothers knowledge,attiude and practic towards iron dificiency anemia and their preventive behaviour against this problem in their children by using precede model.analysis of data was done with precede model by path analysis method.results indicated that the following variables had direct significant effects on mothers preventive behaviors:mothers knowlege,attitude,diet advice from relatives and friends,willingness to participate in relevant classes,availability of ferrus sulfate drop and the financial ability of the family.moreover,mothers preventive behavior had direct significant affect on variable of anemia.finally,the study indicate that PRECEDE model(predisposing enabling and reinforcing factors) could be used to predice preventive behavior of IDA.
https://jkmu.kmu.ac.ir/article_33790_024d32c4eaef329dfd6b7746a145d3b2.pdf
PRECEDE model
iron deficiency anemia
children aged 1-5
path analysis
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
102
105
33791
Epididymal adenomatoid tumor:report of two cases
A.A Ketanchi
1
Assistant professor
The bening tumors of paratesticular tissues are uncommon and their frequency rating is as follows:adenomatoid tumor,leiomyoma and papilliferous cystadenoma.this paper reports two new cases of epididymal adenomatoid tumor in 43 and 25 years old males presented with testicular pain and a mass in their testes.diagnosis was achieved through physical examination and sonography with confirmed pathological examination.a simple tumorectomy was perfomed for both cases.
https://jkmu.kmu.ac.ir/article_33791_2d925f96d777699ad7213172fd5ce478.pdf
epididym
adenomatoid tumor
paratesticular tumor
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
106
109
33792
A case report of beckwith-wiedemann syndrome
B Basiri
1
M SHekohi
2
..
Assistant professor
beckwith and wiedemann for the first time described a syndrome characterised by macroglossia,macrosomia and omphalocele.nowadays inaddition to the above symptoms,visceromegaly,mild microcephaly,facial nevus flammeus,earlobe cerase,persistent neonatal hypoglycemia,and polycythemia are also considered various manifestations of Beckwith-Wiedemann syndrome.
This study report a female neonate with macrosomia,macroglossia,earlobe crease,exomphalus,infraorbital crease,facial nevus flammeus.persistent hypoglycemia and polycythemia.the patient was first treated for hypoglycemia.two days later she was lethargic and had convulsions.the patient was suspected to have septicemia and was treated whit antibiotic.laboratory findings include hypoglycemia,and culture resultes were positive for E.coli in CSF,blood and ophthamal discharge.eventually the patient died due to gram-negative septicemia.
https://jkmu.kmu.ac.ir/article_33792_a7e79743f5ed32bb7f56454c82029bb5.pdf
beckwith-wiedimann syndrome
Hypoglycemia
macrosomia
macroglossia
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
2002-03-01
9
4
110
113
33793
A case report of wound myiasis caused by lucilia sericata
S.A Talari
1
F Sadr
2
A DOrodgar
3
M Arbabi
4
Associate professor
Assistant professor
.
.
lucilia sericata larva is an obligatory parasite which causes myiasis in animals and rarely in humans as an ectoparasite.it belongs to the family of arthropoda and has many forms incuding egg,larva,nymph and adult.infestation in humans and sheep occursin wounds,mouth,ear,eye,and nose.infestation with this parasite causes itching,pain,inflammation,erythema,eosinophilia and secondary bacterial infection.this study introduces a case of myiasis caused by lucilia sericata larva of the left hand wound in shahid Beheshti hospital,Kashan 2000.the case is a 36 years-old mman,with 12 years history of addiction to opium,living in Kashan,which has had heroin injections since 3 years ego.after an overdose was reffered to Shahid Beheshti hospital in Kashan with signs of hypoxic encephalopathy,decreasing mental alertness and coma.He was diagnosed as HB,Ag,HIV negative and HCV positive.liver function tests LFT,CBC,ESR were normal however staph aureus was isolated from his wound.also,a total of 38 alive larvae in stage 3 were removed from his wound.the larvae in laboratory changed to adult forms and adult flys proved to be lucilia sericata.considering the above report,and observation of lucilia sericata in Kashan it is recommended that attending physicians,who observe similar clinical signs,refer the patients to the laboratory for further evaluation and possible diagnosis of this parasite.
https://jkmu.kmu.ac.ir/article_33793_a5e719466bf6a780f5562325be3ff63f.pdf
Lucilia sericata
myiasis
Kashan