eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
1
7
34287
Oral glucose tolerance test,blood insulin level and lipids metabolism in women with idiopathic hirsutism
A.A Abdolfotohi
1
I Keymaram
2
E Khodaiani
3
Associate professor
Associate professor
It is becoming apparent that is patients with hirsutism, metabolic aberrations are of greater health importance rather than unwanted hair growth.in this respect , evaluation of carbohydrate and lipid metabolism was carried out on a group of 92 women with idiopathic hirsutism(IH).these were divided into: obese and non-profit obese groups.seventy healthy subjects were also taken as control group.there was no significant difference in the levels of FSH ,LH, estrogen, progesteron and prolactin between IH patients and control group.but the levels of total testestron( p< 0.01) and DHEA ( p< 0.05) was significantly increased in the IH patients as compared with the control group.the glucose tolerance test and insulin response to the oral glucose as well as concentration to triglycerides was increased in the IH patients.in non-obese IH( NOIH ) group the glucose tolerance was significantly higher than that of the obese IH ( NOIH) group.the insulin response to oral glucose was higher in the OIH group as compared with the NOIH group.HDL- C level was significantly declined in the IH patients(p< 0.01) , but the levels of LDL-C and total cholesterol had no significant differences between patients and control group.fasting blood insulin and total testestron was correlation with increased triglycerides and decreased HDL- C (p<0.05). Based on these results further investigation are recommended to find the involved mechanisms in metabolic aberrations in patients with idiopathic hirsutism.
https://jkmu.kmu.ac.ir/article_34287_e488616df7e55a13ff7d0c6e0d721fc9.pdf
Idiopathic hirsutism
insulin
Glucose
Lipids
sex hormones
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
8
16
34288
A survey of height and weight of children and adolescents iI Kerman ,Iran, in 1997
A Ahmadi
1
A.A Vahidi
2
Associate professor
Assistant professor
The aim of this study was to determine the height(Ht) and weight(Wr) of Kermanian student aged 6-17 years.for this purpose in a cross- sectional study by a multi- stage sampling method,3419 healthy girls and 3287 healthy boys were studied for Ht and Wt. For a more precise evaluation of results the students were divided into two groups: 6-10 ( first group) and 11-17 years old( second group). In the first group there was no significant difference between the Ht and the Wt of girls and boys, but only the 6 years old boys were taller and heavier than their peers ( p<0.05). In 10-13 years children ,boys were shorter and lighter than girls but after that their Ht and Wt surpassed the girls. Comparing with the national studied , in the first group (6-10 years old) the median Ht of girls and boys in Kerman city is significantly higher than those of their peers in Shiraz, Mashhad and Golan. The median Wt of this group is significantly higher than Shirazian children but significantly lower than Tehranian peers. In the second group(11-17 years old) the median Ht of girls and boys in Kerman city is significantly higher than that of their peers in Mashhad, Tehran, Golan and Isfahan. The median Wt of the boys in this group is higher than that of their peers in Mashhad, Golan and Isfahan but lower than their peers in Tehran. The median Wt of the girls is higher than their peers in Isfahan. Comparing with NCHS data, the Ht and Wt of Kermanian girls and boys are significantly lower than those of their American peers. Therefore , using the foreign charts causes false evaluation of many children as being underweight or short stature. Therefore it is suggested that in Iran and preferably in any geographic part of it, growth chart s for prepared based on the special local indices.
https://jkmu.kmu.ac.ir/article_34288_1aa217c3ebc5d713cca44301ff4c7323.pdf
Height
Weight
growth pattern
student s
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
17
22
34289
The comparison of a,AT phenotypes in some HBsAG-positive patients with and without cirrhosis in Tehran
A Sahebghadame lotfi
1
R Malekzadeh
2
B Milani
3
Assistant professor
professor
Alpha-1- antitrypsin is the most important serine protease inhibitor in serum. This protein has several phenotypes. Some of these phenotypes such as MZ, M, Z, M, S, MS, ZZ,…. Cause a,AT deficiency which leads to damage in many tissues such as liver, lung, kidney. 60 patients and 28 healthy individuals (control group), aged 7-65 years old were studied for a,AT activity and a,AT phenotypes. The control group with HBsAg-negative were selected according to the physician confirmation and liver function tests. The test group who were HbsAG-positive were divided into two groups. The first group without cirrhosis and in the second group hepatic cirrhosis based on the pathological report was confirmed. In the control group the phenotypes of P.MM was 100℅, and in positive-HBs-Ag patients the prevalence of PiMM, PiM2 and PiMS were 80℅, 11℅, and 8.14℅ respectively . There were significant difference s in the phenotypes among the three groups(p<0.05). Based on our results patients with a,AT deficiency infected with HIV are at the higher risk of cirrhosis than those with normal a,AT phenotypes.
https://jkmu.kmu.ac.ir/article_34289_071d26c147e409eca5e44fb092a50268.pdf
alpha-1-1 antitrypsin
HasAg
Iso electric focusing
cirrhosis
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
23
28
34290
Comparison of body image in Donors and recipients, pre and post ranal transplantation in selected Tehran and Isfahan hospitals in 1997-98
M Azarbarzin
1
S Kohan
2
S Mohammad- Alizadeh
3
S Forohari
4
Msc student
Kidny transplantation is often accompanied by psychological problems. Alteration in the body image is one of these problems.Body image is defined as one,s perception of this physical status which disturbed by alerted body structure, function or appearance. In this respect , this study was done to compare the body image of Donors and recipients of renal transplantation before and after the transplantation . The samples were 50 Donors and 50 recipients who had referred to selected hospitals of Tehran, and Isfahan during a period of six months. Data collection instrument was a questionnaire, based on five- point Likely scale. For data analysing ,t- test, paired-test, one way ANOVA and Yucky test were used. The results revealed that body images of Donors ,after transplantation were significantly lower than before transplantation and for recipients it is just the opposite (p<0.0001). Furthermore significant differences were observed in the body image scores alteration of recipients depending an age (p<0.01), education (p<0.05), and job (p<0.04). In the Donors group significant differences were also related to education (p<0.05) and family relation with recipients(<0.04). The Donors in the age group 27-35 years with university degrees and having official jobes and recipients whit education of diploma or higher and those who had received the transplanted kidny from a far relative or a friend were at the risk of alteration in their body image more than others.
https://jkmu.kmu.ac.ir/article_34290_865d569cff84775d3a7197cd40298b14.pdf
body image
renal transplantation
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
29
38
34291
Plasmid- mediated cefotaxime and ceftizoximd resistance in Ten strains of klebsiella pneumoniae isolated from hospitals in Kerman,Iran
M.R Shakibaei
1
A.H GHolamali big
2
Assistant professor
Klebsiella pneumonia is a gram negative bacillus of which it's resistant strains are a common source of nosocomial infections . The goal of this study is determination of drug sensitivity of these resistant strains, and study of causes involved in the resistant especially the presence of plasmid. Ten different strains of klebsiella pneumoniae were isolated from clinical specimens collected from microbiology laboratories of different hospitals in Kerman city,Iran. The strains were isolated from blood, urine, stool and wound infections. Genus and species of the organisms and the existence of large capsule were confirmed by bacteriological tests. The susceptibility of the strains different antibiotics were determined by disk diffusion method. The minimum inhibitory concentration(MIC) of the antibiotics was also determined. All of the isolated bacteria were resistant to ampicillin, penicillin G., amoxicillin, cloxacillin, co-trimoxazols, cephalexin cefzoline, and cephalexin. Organisms were also exhibited moderate resistance to tetracycline, chloramphenicol and erythromycin , while, they were sensitive to amikacin, gentamicin, kanamycin and rifampicin. Among them, strains 2,4,9 and 10 showed highest MIC toward cefotaxime and ceftizoxime (MIC>512 mg/L). Conjugation technique with membrane filter along with plasmid isolation of these 10 isolated strains and observation of the plasmid band on the 0.7℅ agarose gel, revealed that resistance to cefotaxime and ceftizoxime are plasmid – mediated and can transferred from K-9 to K-8 by conjugation transfer of CTX and CAZ genes to the recipient cells. Interspecies conjugation to E.coli S G20030.1 , however, was negative.
https://jkmu.kmu.ac.ir/article_34291_536124f572ebe7b991ff575f4a94e961.pdf
Klebsiella pneumoniae
Antibiotics resistance
Plasmid
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
39
44
34292
The role of bronchiL brushing through fiber-optic bronchoscopy in rapid diagnosis of sputum smear negative cases of pulmonary tuberculosis
S.A.R Habibi-Khorasani
1
S.A Tavakolinejhad
2
Assisant professor
The aim of this study was to determine the ability of bronchial brushing in rapid diagnosis of pulmonary tuberculosis in patients with negative sputum smear.this retrospective study was performed on 188 patients who were suspected of pulmonary tuberculosis and had undergone fiberoptic bronchoscopy during the period of 1990 to 1996 in Kerman university No.1 . Although their history, physical and radiological finding were suggestive of active pulmonary tuberculosis , the sputum smears were negative in the majority of the cases. The specimens obtained trough fiberoptic bronchoscopy by bronchial brushing were stained by Zidhl-Neelson method and were examined for the presence of AFB. Among 180 patients , 65 cases (35℅) were positive for AFB. These patients also were studied for radiographic changes. The most common radiological patterns were first, consolidation and then, infiltration . Since this technique can be performed in just 3 days it can be used for rapid diagnosis in such patients.
https://jkmu.kmu.ac.ir/article_34292_50755f5bd5efaba4691e3412fb1ab103.pdf
Bronchial brushing
fiberoptic bronchoscopy
Pulmonary tuberculosis
sputum smears negative
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
45
49
34293
A survey on the influence of intra- peritoneal injection of hydrocortisone in the rate of intra abdominal adhesion bands in rats
H Zenalinejhad
1
M Baghaei vaji
2
A Ramezani
3
Assistant professor
Assistant professor
Occurrence of adhesions after pelvic and abdominal surgery is a well known problem. Previous surgical procedures are by far the most common cause of intra abdominal a adhesion. In over 10℅ of infertile women, adhesion formation is the main cause of their problem. Moreover postoperative adhesions are the most common cause of intestinal obstruction in the Western world. Although the cause of adhesion is unknown, but any trauma with mechanical, chemical, physical or infectious origin, to the peritoneum can cause a response in the peritoneal surface with subsequent adhesion formation. It is known that the basis of most studies, investigating the reduction of adhesion bands, are administration of anti- inflammatory and immunosupprestive drugs. In this study too, the intraperitoneal injection of hydrocortisone acetate for prevention of adhesions has been evaluated.fourteen rats with the mean weight of gr+_11.02 (X+_SD) were selected. After laparotomy and crashing the peritoneum covering uterus the peritoneal cavity was poured over by talc powder suspension which led to adhesion formation. Then animals were divided into two groups : the first group (n=7) received intraperitoneal injection of hydrocortisone acetate (25mg/kg) and the second group (n=7) received normal saline in the same volume. On the 28 th postoperative day, rats were killed and after relaparatomy they were evaluated with swolin system for adhesion formation. In the case group all the rats had grade II adhesion while in control group 6 rats had grade II and one rat had grade III adhesion. There was no significant difference in the rate of adhesion between two groups. Therefore according to this study, it can be concluded that intraperitoneal injection of hydrocortisone has no effect in decreased adhesion formation.
https://jkmu.kmu.ac.ir/article_34293_816c68bef7b38d3f2ba59b99a492fea4.pdf
Adhesion
hydrocortisone acetate
intraperitoneal injection
Rat
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1997-12-01
5
1
50
60
34294
Radiation hormesis and adoptive response induced by low doses of limiting radiation
S.M.J Mortazavi
1
H Mazdarani
2
T IKOSHIMA
3
A.A Sharafi
4
Associate professor
professor
Assistant professor
Ionizing radiation has long been known to produce detrimental biological effects. Although these harmful effects are the results of high doses of exposure, some other maladies such as mutation and cancer seems to be induced at low doses of exposure. In recent decades, however, some pioneer scientists have indicated that ionizing radiation like many other essential agents has toxic effects at important doses but low- level ionizing radiation not only is harmless but also has a stimulatory or hermetic effect on the growth of animals and plants. Furthermore, epidemiological studies confirm the results obtained from plant and animal studies and show that low- level ionizing radiation may be essential for life. According to these studies, ionizing radiation, like many other physical or chemical agents ( UV, vitamins, hormones and Trace elements), can be completely beneficial at low doses and harmful at higher doses. It has been indicated that when human cells are exposed to low doses of ionizing radiation and other agents that induce DNA damages, they often become less sensitive to the detrimental effects of higher doses of those agents administered subsequently. This phenomenon has been termed the adoptive response. So, today , some facts such as the necessity of nuclear energy in modern life, areas with high background radiation and a considerable increase in the use of radiography and ratotherapy in medicine , make it necessary to do more researches on the biological effects of low doses of ionizing radiation and especially on some phenomena such as hormesis and adoptive response.
https://jkmu.kmu.ac.ir/article_34294_9147d853b2ff189eeb07fc9ac3d0f4ab.pdf
Hormesis
low dose radiation
adoptive response
cancer