eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
1
7
34363
Study of thr role of afferent C fibers and cholinegic never endings in acute joint inflammation induced by Kaolin in rabbit
R Karbaschi
1
A Khosh baten
2
A.R Askari
3
Associate professor
Associate professor
inflammatory disease such as rheumatiod artheritis increase blood flow to joints.kaolin is one of substances injected into the joints in order to induce experimental acute joint inflammation the aim of this study was to determine the role played by nervous system in this model of acute in flammation.in the rabbit.evans blue technique was used to assess articular inflammation.the results indicated that :1)maximum inflammation accured after 4 hours of 4% kaolin injection,and after this period the intensity of the inflammation was reduced.2) injection of capssacine and substance P antagonist inside the join reduced the inflammation response by 39% and 15% respectively.therefore it can be suggested that afferent Cfibers may play a major in flammation process induced by kaolin,and substance P can be the mediator of the inflammation .in order to determine the role of sympathocholinergic fibers in this inflammation model,sulfate atropin was used locally.injection of this substance did not show a significant effect on inflammation response induced by kaolin.therefore sympathocholinergic system dose not seem to be involved in this model acute inflammation.
https://jkmu.kmu.ac.ir/article_34363_b41589e08ee41100c472aab5112d0286.pdf
Knee joint
acute inflammation kaolin
afferent Cfibers
cholinergic system
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
14
19
38492
Nutritional anemias in pregnant women
A.A Soheili-Azad
1
M Jalali
2
A.GH Jazairi
3
B Golestan
4
the aim of this cross sectional study was to determine anemias due to deficiency of iron,vitamin B12 and folate in pregnant women,who were refered to Shahid doctor mofateh hospital in varamin.in this study hemoglobin value(<11g/dl) was used as the determinant of anemia,therefore,the study was performed on 251 pregnant women.the proportions of women having abortions and cesarean sections were 10% and 14.7%,respectively.in this study,serum folate,RBC folate and serum B12 were determined using RIDA test.based on the hemoglobin (HB),hematocrit(HCT),and mean corpuscular hemoglobin concentration (MCHC) values,26.1%,21.3% and 53% of the mothers were anemic,respectively.based on serum iron,TIBC and transferin saturation rate,serum folate ,RBC folate and serum B12,15.4%,67.5%,49.2%,89.7%,27.4% and 22.2% of the mothers were anemic respectively.the prevalence of anemia due to vitamin B12 deficiency in abortive women(37.5%) were significantly higher than in non-abortive (21%) group(p<0.05).the prevalence of anemia on the basis of serum folate in the abortion group was significantly higher than in the women how had abortion were suffering from serum falate deficinency of which 70.8% were suffering from severe serum folate deficiency,and 29.2% were suffering from a milder form of the deficiency,while 31.8% were suffering from deficiency of folate in RBC,s.the results of this study showed that supplementary folate has to be administered during pregnancy period.
https://jkmu.kmu.ac.ir/article_38492_237f38385978a803a9c5f89ad4669eaa.pdf
Pregnancy
Anemia
nutrition
abortion
Varamin
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
20
25
38493
Epidemiology of preeclampsia in pregnant women referred to Shahid Bahonar hospital of Kerman in 1994
B.B.SH Ali
1
M Janghorbani
2
Assistant professor
Associate professor
pregnancy induced hypertension is a frequent cause of maternal and perinatal mortality and morbidity and it is one of the major obstetric problems.the aim of this study was to determine the incidence and severity of pregnancy induced hypertension disorders of patients referred to Niknafs maternity hospital(the largest maternity center of Kerman) in 1994.data on frequency of neonatal deaths,maternal age,parity,gestational age,underlying disease,fatal hydrops,season,multiparity and recurrence were analysed in relation to hypertension and preeclamosia.among a total of 3339 pregnant women reffering to Niknafs maternity hospital.167(5%,95% confidence interval{CI} 4.3%,-5.8%) were hypertensive of whom 14 (0.4%,95% CL:0.2%,0.7%) had eclampsia,68% (2%,95% CI 1.6%-2.6%) sever preeclampsia and 58(2.6%,95%CI:2%-3.1%) had mild preeclampsia.the everage (standard deviation {SD}) of the patients age was 27.1(6.3) years,more than one third of the patients (37.2%) were 20-24 years old and 1.2% above 40 years.43.8% of patients were primigravida and 25% had more than five pregnancies.the average(SD) gestational age was 36.2(4.3) weeks.95.8% of the patients had no history of previous underlying background disease,only 0.6% had history of diabetes mellitus and/or chronic vascular disease and 3% had chronic hypertension.recurrence occurred in 7.8% of cases.there were 9 cases of dead fetuses(6.25%,95% CI:2.9%-11.5%) among 144 births,and no report was obtained about delivery in 23 cases of them.multiparty and fetal hydrops was not seen in preeclamptic patients.seasonal variation did not influence the incidence of preeclampsia and hypertensive disorders of pregnancy.considering the above findings no significant difference was observed in prevalence of preeclampsia in Kerman in comparison to the results reported from the other parts of the world.
https://jkmu.kmu.ac.ir/article_38493_cd6bd9822b43a20ebdc85324587469ca.pdf
pregnancy induced hypertension
preeclampsia
Eclampsia
seasonal affective disorder
Incidence
Epidemiology
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
8
13
38491
Study of the effect of meal frequency in non-insulin dependent diabetic patients
S.A Keshavarz
1
F Azamtaleban
2
CH Farhomand
3
Associate professor
Associate professor
the purpose of this semi-experimental,cross-over and perspective study was to investigate the effect of the number of the meals on fasting serum,colestrol,triglyceride,glucose,and serum glucose at time intervals of 0.5,1,1.5 and 2 hours after eating a standard breakfast(BTT) included 125g of taftoon bread,cheese 40g,50g of 2.5% milk which contains 470kcal of energy,75g of carbohydrate,20g of protein and 10g of lipid.the subjects were 12 NIDDM (non insulin dependent diabetes mellitus) patients referring to the Tehran institute of endocrinology and metabolism.information was obtained regarding the intake of food using a questionaire over 3 days of food consumption.the subjects were divided into two groups at random and each group was given one of the 4 meal or 8 meal diets which contained equal calories.the subgroups were on the diets for a period at 2 weeks and the time interval between the two periods was 18+_2.16 days.in the second phase of the study wach group used a different recommended diet.Initial and final(i-e.at the end of either period) blood analysis was performed on all the subjects in the reference laboratory.the paired t-test was used to test the hypotheses.the results are as followe:p1.there was nostatistically significant difference observed between the two subgroups with regard to today weight,BM1and the amounts of drugs consumed during the study period. 2.the blood glucose concentrations 0.5,1,1.5 and 2 hours after B.T.T at the end of the high meal frequency diet were significantly lower the initial values,(p<0.002). 3.the fasting blood glucose concentration at the end of the high-meal frequency diet was significantly lower than the initial value(p<0.02). 4.the difference between blood glucose serum at the end of the high meal frequency period and at the end of the low meal frequency period was also statistically significant)p<0.05). 5.despite the high decrease in mean triglyceride level after 2 weeks of high frequency meal diet consumptiom,the differences as compared to the low-frequency and regular diets,were not significant.it can be concluded that an 8 meal diet brings reductions in fasting blood glucous levels,and improves glucose tolerance in NIDDM patients.
https://jkmu.kmu.ac.ir/article_38491_23e74348aba3bedb062e0ec9695e905d.pdf
meal frequency
non insulin dependent diabetes
Blood glucose
Triglyceride
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
26
31
38676
study of antipruritic effect of citrus bigaradia(sour orange)
f SHarififar
1
F Moatar
2
A.A Mohaghegh zadeh
3
Associate profssor
pruritis is a common dermatic condition which can be the symptom of many localized and systemic infections,for which these is no specific treatment.most of the drugs used only lessen the symptoms,and they all have side effects.based on this,and since in Iranian traditional medicine sour orange fruit has been implicated as having antipruritic effects,in this study the latter effect was studied.at first the plant was gathered, identified,scientifically named and eatracted by percolation wath ethanol 80%.the cream of the plant and its relevant placebo was formulated using vanishing cream base.on the basis of the spilker,s novel double blind method,antipruritic activity of sour orange cream,calamin cream and placebo on 27 volunteers were evaluated during 110 minutes.in this expriment the bulb of scilla was examined using ratio 4mg in 5ml water as pruritogen agent.the results were evaluated with pair t-test.the findings indicated that calamin and sour orange creams had the false level of 10% and 20% in proportion to placebo,therefore we can conclude that despite on indication of a relative improvement,we can not conclude a definite effect based on the sample size in this study.
https://jkmu.kmu.ac.ir/article_38676_f583a5d889e99859113fabd50b0fa77d.pdf
antipruritics
citrus fruite
bioflavonoids
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
32
37
38677
Study of calcium metabolism in Beta-Talassemia major patients
M GHanei
1
M Hekmat
2
A.GH Mashhadi esmaeil
3
Assistant professor
disturbances in calcium metabolism and both impairment are some of the known complications observed in beta thalassemia major patients.although iron deposition has been recognized to be the main factor for organ dysfunction in these patients,the relatively low prevalence of hypoparathyroidism has led to giving more emphasis to Ca metabolism disturbance among others.availability of more patients compared to the previous studies was the determining facto in doing this study.in this descriptional study of 700 major thalassemic patients in seyed-al-shohada hospital in june 1995,a population of 153 patients were selected based on simple random sampling before transfusion.analusis of serum Ca,p,alkaline phosphatase,ferretin,Mg,albumine and liver function tests were performed prior to transfusion and on fasting blood.samples were taken on average a month after blood transfusion history was taken and with proper grouping.the results were analused.ten patients(6.3%) had hypocalcemia and one patient with a low serum PTH,low serum albumin in another patient rejected true hypocalcemia.all other patients had normal PTH& serum P,expect one patient who had low serum P.thus it is possible to conclude that patients with hypocalcemia,low or normal PTH, high or normal P had hypoparathyroidism.there was also a significant correlation between different age groups & ferritin,BMI:correlation between different BMI groups & age,Ca was significant,too.yet,the correlation between serum P& number of transfusion in tha last three months was significant(p<0.05).the relative prevelance of hypothroidism was about 3.6%.it seemed that calcium disturbance in these patients was due to factors other than low PTH.the correlation between Ca & number of transfusion in the last three months suggests that P increases has been the result if an increase in hemolysis.this also suggests that because of the same reason & also due to malabsorbtion &liver dysfunction,there has been a disturbance in Ca metamolism.these rerults imply that prescribing Ca & vit D will be applicable and useful in most of the patients.
https://jkmu.kmu.ac.ir/article_38677_6cc45a80bcf1c26b8e90e9afcc374641.pdf
Beta Thalassemia Major
Calcium
parathyroid hormones
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
38
43
38678
Assesment of the work of satff nurses in determining body temperatures of hospitalized children in Kerman university hospital No1
M Moshiri
1
GH.A Amir-Ostovar
2
A.R Yargholi
3
in this study the accuracy of one of the vital signs(boyd temperature) reported by the nursing staff was compared with the reporting of the control group,in order to find the problems and ways to solve them.to do this,117 body temperatures reported from hospitalized patients in pediatrics wards in Kerman university No1 hospital were analused.samples were gathered by clustering method from different working sifts.patients body temperatures were taken from the armpit and were compared with the temperature recorded by the nurses in the patients files.of 117 recorded temperatures measured in different patients a total of 102 cases met the criteria and were included in the study.the mean recorded temperatures in the nursing group was 73.5+_0.26c and in control group was 36.53+_0.72c (p<0.0001).the range of variation in the two groups was -2.5 to _2.4c with the mean of deviation 0.75+_0.5c.based on this,we fined four levels of differences:with an error 0 to 0.5c(39.2%).a mild error 0.6to 1 c (37.3%).a moderate error 1.1 to1.5(16.7%),and a gross error more than 1.5c(6.9%).the differences observed between the two groups were statistically significant.due to the decrease in sensitivity of armpit temperatures when the body temperature is high and an increase in personnel,s error,we recommend that in the patients in whon the body temperatures could be dangerous,body temperature should be taken analy and by an experienced personel.
https://jkmu.kmu.ac.ir/article_38678_d97b6acf192eefa4a9aaab1a7b5be784.pdf
Nursing
body temperature
meansurement error
Pediatrics
axillary temperature
eng
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
1996-12-01
3
1
44
49
38679
A report of two cases of pyknodysostosis in two children
F GHazanfari pour
1
Assistant professor
pyknodysostosis is a rare bone disease characterzed with short stature,wide fontaneles,small chin,hyperdensity of bones,erosion of tufts of the disatl phalanges,and narrowing of the mandibular angle. pyknodysostosis is inheritted as an autosomal recessive disease and may be seen in both sexes at any age.the patients have normal life span.short stature and bone fractures are their major problems.in this report two children 1.5 and 4 years old are presented.the former was referred due to Gastroenteritis and tha latter because of delayed closure of the anterior fontanele,and both were admitted in the Kerman university of medical sciences-hospitalNo1.pyknodysostosis was suggested as the probanle disease indicated for these patients and later confirmed by clinical and paraclinical investigations.
https://jkmu.kmu.ac.ir/article_38679_609c2cf3863cdb3e6e0cee7caf0e7a41.pdf
pyknodysostosis
wide fontanele
Short Stature
hyperdensity of bones