%0 Journal Article %T Molecular and Phenotypic Characteristics of Staphylococcus Hominis Isolates From Pediatric Infections %J Journal of Kerman University of Medical Sciences %I Kerman University of Medical Sciences %Z 1023-9510 %A Safari, Fereshteh %A Nikmanesh, Bahram %D 2020 %\ 01/01/2020 %V 27 %N 1 %P 99-105 %! Molecular and Phenotypic Characteristics of Staphylococcus Hominis Isolates From Pediatric Infections %K Staphylococcus hominis %K Biofilm %K Multiresistance %K SCCmec %R 10.22062/jkmu.2020.89601 %X Background: Staphylococcus hominis has been recently emerged as an opportunistic hospital-associated pathogen. The aim of this study was to characterize the antimicrobial susceptibility pattern, biofilm formation, and staphylococcal cassette chromosome mec (SCCmec) types among clinical isolates of S. hominis obtained from pediatric infections. Methods: Totally, twenty- two clinically significant S. hominis isolates, mostly from blood samples, were examined for antibiotic resistance, SCCmec typing, and biofilm formation.  Results: Multiresistance was observed in 86 % of isolates. Among mecA positive isolates (77%), SCCmec type I (28%), III (22%), IV (22%), and non-typeable ones (28%) were detected. More than half of the isolates (54.5%) did not produce biofilm. No significant association was found between biofilm formation and the presence of ica operon. Conclusion: As S. hominis isolates were not strong biofilm producers, biofilm formation cannot be considered as much as important multidrug resistance.in the pathogenesis of isolates. %U https://jkmu.kmu.ac.ir/article_89601_9a147afe5c8055df91da3f57f40416d5.pdf