ORIGINAL_ARTICLE
Prevalence of Alpha-1 Antitrypsin (A1AT) Deficiency among Patients with COPD in Kerman, Iran
Background: One of the genetic risk factors for chronic obstructive pulmonary disease (COPD) is deficiency of Alpha-1 Antitrypsin (A1AT). There is no exact statistics about the prevalence of this disease in different regions of Iran. The present study aimed to determine the prevalence of alpha-1 antitrypsin (A1AT) deficiency in COPD patients in Kerman, Iran. Methods: In the present study, the serum level of AAT in 294 COPD patients visited in the pulmonary clinic center in Kerman, Iran was measured. The diagnosis of COPD was confirmed through history taking and Spirometry before and after using Bronchodilator. Data analysis was done by using t-test and Chi-square test. Results: Among294 studied patients, 223 individuals (75.9%) were male. None of the patients had absolute deficiency of A1AT, and only13 patients (4.4%) had a relative deficiency of A1AT. There was a statistically significant relationship between relative deficiency of A1AT and the severity of COPD in a way that in most of the cases, relative deficiency of this enzyme was associated with severe and very severe airway obstruction. Conclusion: Based on the results of the present study and other similar studies in Iran, absolute and relative deficiency of A1AT in Iran has less frequency compared to other regions of the world and other factors such as cigarette smoking, opium addiction and consumption of fossil fuels have a more significant role in the prevalence of COPD in Iran.
https://jkmu.kmu.ac.ir/article_46770_e2ab61e3246768720dc41898131b2613.pdf
2017-03-01
103
110
Alpha-1 Antitrypsin (A1AT)
Chronic Obstructive Pulmonary Disease (COPD)
Prevalence
Mitra
Samareh Fekri
1
Associate Professor of Pulmonology‚ Cardiovascular Research Center‚ Institute of Basic and Clinical Physiology Sciences‚ Kerman University of Medical Sciences‚ Kerman‚ Iran
AUTHOR
Sayed Mehdi
Hashemi Bajgani
hashemimehdi70@yahoo.com
2
Assistant Professor of Pulmonology‚ Afzalipour Hospital Research Center‚ Kerman University of Medical Sciences‚ Kerman‚ Iran
AUTHOR
Nasrollah
Jamshidi Gohari
n.jamshidi87@gmail.com
3
General Medicine‚ Physiology Research Center, Institute of Basic and Clinical PhysiologySciences, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Nasrin
Bazargan Harandi
4
Assistant Professor of Pediatric Asthma and Allergy and Immunology‚ Afzalipour Hospital Research Center‚ Kerman University of Medical Sciences‚ Kerman‚ Iran
AUTHOR
Mohammad
Rahmatian
m.rahmatian@yahoo.com
5
Vice Chancellor for Treatment‚ Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006; 367(9524): 1747-57.
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Niederlander E. Cause of death in the EU. Statistics in focus - Population and social conditions. Eurostat, European Communities; 2006.
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Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997; 349(9064): 1498-504.
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Global Initiative for Chronic Obstructive Lung Disease [Internet]. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; [cited 2017 Jun 3].Available from: http://goldcopd.org/gold-2017-global-strategy-diagnosis-management-prevention-copd/.
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Siafakas NM. Definition and differential diagnosis of chronic obstructive pulmonary disease. In: Siafakas NM,editors. Management of Chronic Obstructive PulmonaryDisease. European Respiratory Society Monographs; 2006. P. 1-6.
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Lomas DA. The selective advantage of alpha1-antitrypsin deficiency. Am j respir crit care med 2006; 173(10):1072-7.
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Tishler PV, Carey VJ, Reed T, Fabsitz RR. The role of genotype in determining the effects of cigarette smokingon pulmonary function. Genet Epidemiol 2002; 22(3): 272-82.
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Viegi G, Pistelli F, Sherrill D, Maio S, Baldacci S, Carrozzi L. Definition, epidemiology and natural history of COPD. Eur Respir J 2007; 30(5): 993-1013.
8
Crystal RG. Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy. JClin Invest 1990; 85(5): 1343-52.
9
Ritchie RF, Palomaki GE, Neveux LM, Navolotskaia O, Ledue TB, Craig WY. Reference distributions for the positive acute phase serum proteins, alpha1-acid glycoprotein (orosomucoid), alpha1-antitrypsin, and haptoglobin: a practical, simple, and clinically relevant approach in a large cohort. J Clin Lab Anal 2000; 14(6): 284-92.
10
Hill AT, Bayley DL, Campbell EJ, Hill SL, Stockley RA. Airways inflammation in chronic bronchitis: the effects of smoking and alpha1-antitrypsin deficiency. EurRespir J 2000; 15(5): 886-90.
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Greene CM, Hassan T, Molloy K, McElvaney NG. The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and α-1 anti-trypsin deficiency. Expert Rev Respir Med 2011; 5(3): 395-411.
12
Nadi E, Hajilui M, S Abdoli S, Basiri Z. The Prevalence of the Alpha-1 Antitrypsin Deficiency in Patients with Chronic Obstructive Pulmonary Disease. Qom University of Medical Sciences Journal 2011; 5(1): 7-11.
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Brebner JA, Stockley RA. Recent advances in alpha-1 antitrypsin deficiency related lung disease. Expert Rev Respir Med 2013; 7(3):213-29.
14
American Thoracic Society; European Respiratory Society. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med 2003; 168(7): 818-900.
15
Campose MA, Wanner A, Zhang G, Sandhaus RA. Trend in the diagnosis of symptomatic patients with Alpha-1 Antitrypsin deficiency between 1963 and 2003. Chest 2005; 128(3): 1179-86.
16
Stoller JK, Brantly M, The challenge if detection Alpha-1 Antitrypsin deficiency. COPD 2013; 10(suppl 1): 26-34.
17
Antonelli-Incalzi R, Imperiale C, Bellia V, Catalano F, Scichilone N, Pistelli R, et al. Do GOLD stages of COPD severity really correspond to differences in health status? Eur Respir J 2003; 22(3): 444-9.
18
Dahl M, Nordestgaard BG, Lange P, Vestbo J, Tybjaerg-Hansen A. Molecular diagnosis of intermediate and severe alpha-l antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals. Clin Chem 2001; 47(1): 56-62.
19
Rahaghi FF, Sandhaus RA, Rouhani F, Campos MA, Strange C, Hogarth DK, Eden E, Stocks JM, et al. The prevalence of alpha-1 antitrypsin deficiency among patients found to have airflow obstruction. COPD 2012; 9(4): 352-8.
20
Carroll TP, O'Connor CA, Floyd O, McPartlin J, Kelleher DP, O'Brien G, et al. The prevalence of alpha-1 antitrypsin deficiency in Ireland. Respir Res 2011; 12: 91.
21
Silverman EK, Sandhaus RA. Alpha1-antitrypsin deficiency. N Engl J Med 2009; 360(26): 2749-57.
22
Kuca PJ, Campbell EJ, Bednarek M, Zielinski J, Tomkowski WZ. Prevalence of Alpha1-Antitrypsin Deficiency (AATD) In Patients with COPD in Poland. American journal of respiratory and critical care medicine. 2011; 183: A5354.
23
Hogarth D, Sorroche P, Acquier MF, Wolfe K. Prevalence of AAT deficiency in COPD patients in argentina. Am J Respir Crit Care Med 2013; 187: A3678.
24
Spínola C, Bruges-Armas J, Pereira C, Brehm A, Spínola H. Alpha-1-antitrypsin deficiency in Madeira (Portugal): the highest prevalence in the world. Respir med 2009; 103(10): 1498-502.
25
Sitkauskiene B, Serapinas D, Blanco I, Fernández-Bustillo E, Janciauskiene S, Sakalauskas R. Screening for alpha1-antitrypsin deficiency in Lithuanian patients with COPD. Respir med 2008; 102(11): 1654-8.
26
Garcia-Palenzuela R‚ Timiraos Carrasco R‚ Gomez-Besteiro ML, Lavia G, Lago Pose M, Lara B. Detection of alpha antitrypsin deficiency: A study on patients diagnosed with chronic obstructive pulmonary disease in primary health care. Semergen 2016 Jun25 doi :10.1016/J.Semergen Article in press.
27
Aljarallah B, Ali A, Dowaidar M, Settin A. Prevalence of α-1-antitrypsin gene mutations in Saudi Arabia. Saudi J Gastroenterol 2011; 17(4):256-60.
28
De Serres FJ, Blanco I, Fernández-Bustillo E. PI S and PI Z alpha-1 antitrypsin deficiency worldwide. A review of existing genetic epidemiological data. Monaldi Arch Chest Dis 2007; 67(4):184-208.
29
Hutchison DC. Alpha 1-Antitrypsin Deficiency in Europe: geographical distribution of Pi Types S and Z. Respir Med 1998; 92(3):367-77.
30
Geramizadeh B, Jowkar Z, Karami L, Masoumpour M, Mehrabi S, Ghayoumi MA. Alpha-1 antitrypsin deficiency in Iranian patients with chronic obstructive pulmonary disease. Iran Red Cresent Med J 2013; 15(11): e7508.
31
ORIGINAL_ARTICLE
The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer
Abstract Background: Breast cancer is the most common fatal cancer among women worldwide and it has an increasing rate in Iranian women. The aim of this study was to determine the relationship of gravidity with removed lymph nodes and involved lymph nodes after mastectomy surgery in women with breast cancer. Methods: In this descriptive-analytical study, 111 women with breast cancer, who had undergone mastectomy surgery, were studied. Demographic and clinical characteristics of patients were extracted from their medical files and recorded in a questionnaire. Data were analyzed through SPSS 22 and by using descriptive statistics, ratios differences, mean differences and linear regression. Results: Mean age of patients was 49.8± 10.9 years and mean BMI was 27.4 ± 5.4 Kg/m2. Mean number of removed lymph nodes was 7.8 ± 5.2 and in 50% of the patients, mean number of involved lymph nodes after the surgery was 4.2 ± 3.5. The disease was significantly more prevalent among those who were employed, married, had academic education, and aged over 45 years. According to Linear regression model, each 1.06 year age increase was significantly associated with one more removed lymph node and each gravidity increase was associated with one less removed lymph node and approximately two more involved lymph nodes after the surgery. Conclusion: The results showed that age and gravidity are the most effective factors in the development of lymphadenopathy, especially in increasing the involved lymph nodes after the surgery. Therefore, enhancing the awareness of women about appropriate screening methods for early detection of breast cancer and regular check-ups after surgery is essential to reduce the probable problems.
https://jkmu.kmu.ac.ir/article_46773_2c478a8ee54a49a8341f1538ed51e495.pdf
2017-03-01
111
117
breast cancer
Surgery
Pregnancy
lymph node
Morteza
Hashemian
hashemianmortezaaaa@yahoo.com
1
Assistant Professor, Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Mohammad Reza
Aflatoonian
2
Assistant Professor, Bam University of Medical Sciences, Bam, Iran
AUTHOR
Behnaz
Aflatoonian
3
Researcher, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Mohammad Esmaeil
Akbari
drakbari.drakbari@gmail.com
4
Professor of Endocrine surgery, Cancer Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran
LEAD_AUTHOR
Sakorafas GH, Krespis E, Pavlakis G. Riskestimation for breast cancer development; aclinicalperspective. SurgOncol 2002; 10(4): 183-92.
1
ChuKC, Tarone RE, KesslerLG,Ries LA, Hankey BF, Miller BA, Edwards BK. Recent trends in U.S. breast cancerincidence, survival, and mortality rates.JNatl Cancer Inst 1996: 88 (21): 1571-9.
2
World Health Organization (W. H. O). Fact sheet N 297 February 2009; Available at: http://search.who.int/search?q=Fact+sheet+N+297+February+2009&ie=utf8&site=who&client=_en_r&proxystylesheet=_en_r&output=xml_no_dtd&oe=utf8&getfields=doctype
3
Akbari A, RazzaghiZ, Homaee F, Khayamzadeh M, MovahediM, Akbari ME. Parity and breastfeeding are preventive measures against breast cancer in Iranian women.Breast Cancer 2011; 18(1):51-5.
4
Mousavi SM, Montazeri A, MohagheghiMA, Jarrahi AM, Harirchi I, NajafiM, Ebrahimi M. Breast cancer in Iran: anepidemiological review. Breast J 2007; 13(4): 383-91.
5
LamyianM, Heidarnia AR, Ahmadi F, FaghihzadehS, AguilarVafaie M. Women’s prospect of breast cancer early detection behavior: a qualitative research. J BirjandUniv Med Sci 2008; 15 (3):88-102.
6
Khodaparast M. The effectiveness of cognitive-behavior interventions on depression and anxiety in cancer patients under chemotherapy [dissertation]. Tonekabon: Islamic Azad University 2011.
7
Ghiasvand R, Bahmanyar S, ZendehdelK, Tahmasebi S, Talei A, Adami H-O, CnattingiusS.Postmenopausal breast cancer in Iran; risk factors and their populationattributable fractions. BMC Cancer 2012; 12(1):414.
8
Brady-West DC, Graham SA. Prevalence of risk factors in breast cancer patients at the university hospital of the West Indies.West Indian Med J 2000; 49(2): 161-3.
9
Hertz-Picciotto I, Tseng M, Newman B, Schroeder J, Vine M. Breast cancer and lactation history in Mexican women. Am J Epidemiol 1998; 147(8): 795-6.
10
Boyd NF, Byng JW, Jong RA, FishellEK, Little LE, Miller AB, Lockwood GA, TritchlerDL, Yaffe MJ. Quantitativeclassification of mammographic densitiesand breast cancer risk: results from theCanadian National Breast ScreeningStudy.JNatl Cancer Inst 1995; 87(9):670-5.
11
Romieu I, Hernández-Avila M, Lazcano E, Lopez L, Romero-Jaime R. Breast cancer and lactation history in Mexican women. Am J Epidemiol 1996; 143(6): 543-52.
12
Lee HP, Gourley L, Duffy SW, Estève J, Lee J, Day NE. Risk factors for breast cancer by age and menopausal status: a case-control study in Singapore. Cancer causes control 1992; 3(4):313-22.
13
American Cancer Society (ACS), cancer Facts & Figures, (2008), Atlanta: GA, American Cancer Society; 2008
14
Fentiman IS. Fixed and modifiable riskfactors for breast cancer. Int J ClinPract2001: 55(8): 527-30.
15
Herdy V. Education: a key factor in fighting breast cancer. New York: Inter press services; 1998
16
Statistical Centreof Iran. National Population and Housing Census, 2011: Selected Findings. Tehran: Statistical Centre of Iran; 2012.
17
Ziaeibigdeli M, Kalantari S, Alizadeaghdam M. The Relationship between Fertility Rate and Socio-Economic Development. Social Welfare Quarterly 2006: 5 (21) :123-40
18
Baniasadi M, Aflatoonian MR, Rooholamini R, Aflatoonian B, Abbasi R. Effective Internal Factors in Improvement of Patients Undergoing Breast Cancer Surgery Using a Logistic Regression Model.Iranian Journal of Epidemiology 2014; 10(1): 9-14.
19
Rajaeefard A, Mohammad-Beigi A, Mohammad-Salehi N. Estimation of natural age of menopause in Iranian women: A meta-analysis study. koomesh 2011; 13 (1) :1-7.
20
ORIGINAL_ARTICLE
Phacotrabeculectomy and Implantation of Intraocular Lenses with Releasable Sutures and Antimetabolite Agents: Efficacy and Safety
Abstract Background: The aim of this study was to evaluate the efficacy and safety of phacoemulsification and the implantation of intraocular lenses (IOL) combined with trabeculectomy supplemented by releasable sutures and antimetabolite agents. Methods:Phacotrabeculectomy was performed in 36 eyes of 30 patients who hadmedically uncontrolled Intraocular pressure (IOP) or were nonreliable for medical therapy and had significant cataract, or had low Visual Activity (VA) due to cataract and simultaneous uncontrolled or medically controlled IOP with at least 2 medications. Mitomycin C (0.02%) for 1-3 minutes was applied in all cases. Scleral flap was sutured with permanent (loose) and releasable (tight) 10-0 nylon sutures. The releasable sutures were removed in the first to third postoperativeweeksif IOP was more than 12mmHg. If bleb was vascularized or flat, and IOP was high or borderline (>16mmHg), 5FU was injected subconjunctivally 1-3 weeks after the surgery. If postoperative IOP was more than target pressure, antiglaucoma medications were used. Results:Eight eyes (22.2%) required releasable suture removal. Mean preoperative IOP was 28.4±9.4 (12-52) mmHg. Totally, 33 eyes (91.7%) had primary open angle glaucoma, two eyes (5.5%) had posttraumatic glaucoma and one eye (2.8%) had exfoliative glaucoma (XFG). Mean postoperative final IOP was 12.1±3.9 (5-22) mmHg (p <0.0001). Preoperative VA was 0.5mCF (log Mar=2) to 20/200 (log Mar=1). Mean VA was 3mC.F (Log Mar=1.3±0.4). Postoperative VA was 20/200 (log Mar=1) to 20/20 (log Mar=0) and mean postoperative VA was 20/60 (log Mar=0.57±0.46) (p <0.0001). Mean number of required medications to control IOP was 2.58±0.09 (2-4) preoperatively and 0.58±0.15 (0-3) postoperatively (p <0.0001). Early postoperative complications were flat anterior chamber in 3 eyes (8.3%), postoperative uveitis in 3 eyes (8.3%) leakage in 3 eyes (8.3%) and choroidal effusion in 1 eye (2.8%). Conclusion: It seems, this method is an effective and safe procedure for patients with coexisting cataract and glaucoma.
https://jkmu.kmu.ac.ir/article_46774_8d68e1f0045f2d8b68c5ab19b2497a0f.pdf
2017-03-01
118
124
Phacotrabeculectomy
Releasable suture
Antimetabolite agents
Ali
Sharifi
a_sharifi@kmu.ac.ir
1
Associate Professor, Department of Ophthalmology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Azadeh
Kazemipoor
sharifihami@yahoo.com
2
General Practitioner, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Hamid
Sharifi
sharifihami@gmail.com
3
Associate Professor, HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Future Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Dulku S. Trabeculectomy success rates. Ophthalmology 2012; 119(10): 2194-5.
1
Gavin EA, Mahroo OA, Lim KS. Limbus vs. Fornix-Based Trabeculectomy Results. Ophthalmology 2012; 119(10): PP 2196.
2
Jampel HD, Solus JF, Tracey PA, Gilbert DL, Loyd TL, Jefferys JL, et al. Outcomes and bleb-related complications of trabeculectomy. Ophthalmology 2012; 119(4): 712-22.
3
Landers J, Martin K, Sarkies N, Bourne R, Watson P. A twenty-year follow-up study of trabeculectomy: risk factors and outcomes. Ophthalmology 2012; 119(4): 694-702.
4
Solus JF, Jampel HD, Tracey PA, Gilbert DL, Loyd TL, Jefferys JL, et al. Comparison of limbus-based and fornix-based trabeculectomy: success, bleb-related complications, and bleb morphology. Ophthalmology 2012; 119(4): 703-11.
5
Bowman R, Hay A, Wood M, Murdoch I. Combined cataract and trabeculectomy surgery for advanced glaucoma in East Africa; visual and intra-ocular pressure outcomes. Eye 2010; 24(4): 573-7.
6
Broadway DC, Bloom PA, Bunce C, Thiagarajan M, Khaw PT. Needle revision of failing and failed trabeculectomy blebs with adjunctive 5-fluorouracil: survival analysis. Ophthalmology 2004; 111(4): 665-73.
7
Simsek T, Citirik M, Batman A, Mutevelli S, Zilelioglu O. Efficacy and complications of releasable suture trabeculectomy and standard trabeculectomy. Int Ophthalmol 2005; 26(1-2): 9-14.
8
Stark W, Goyal R, Awad O, Vito E, Kouzis A. The safety and efficacy of combined phacoemulsification and trabeculectomy with releasable sutures. Br J Ophthalmol 2006; 90(2): 146-9.
9
Berestka JS, Brown SV. Limbus-versus Fornix-based Conjounctival Flaps in Combined Phacoemulsification and Mitomycin C Trabeculectomy Surgery. Ophthalmology 1997; 104(2): 187-96.
10
Shingleton BJ, Chaudhry IM, O’Donoghue MW, Baylus SL, King RJ, Chaudhry MB. Phacotrabeculectomy: limbus-based versus fornix-based conjunctival flaps in fellow eyes. Ophthalmology 1999; 106(6): 1152-5.
11
Tezel G, Kolker AE, Kass MA, Wax MB. Comparative results of combined procedures for glaucoma and cataract: I. Extracapsular cataract extraction versus phacoemulsification and foldable versus rigid intraocular lenses. Ophthalmic Surg Lasers 1997; 28(7): 539-50.
12
Cotran PR, Roh S, McGwin G. Randomized comparison of 1-site and 2-site phacotrabeculectomy with 3-year follow-up. Ophthalmology 2008; 115(3): 447-54
13
Storr-Paulsen A, Bernth-Petersen P. Combined cataract and glaucoma surgery. Curr Opin Ophthalmol 2001; 12(1): 41-6.
14
Paul C, Sengupta S, Paul A. Comparison of phacoemulsification versus phacotrabeculectomy in the treatment of patients with chronic angle closure glaucoma and concomitant cataract. J Clin Ophthalmol Res 2014; 2(2): 93-8.
15
Kleinmann G, Katz H, Pollack A, Rachmiel R, Zalish M. Comparison of trabeculectomy with mitomycin C with or without phacoemulsification and lens implantation. Ophthalmic Surg Lasers 2002; 33(2): 102-8.
16
Kuroda S, Mizoguchi T, Terauchi H, Nagata M. Trabeculectomy combined with phacoemulsification and intraocular lens implantation. Semin Ophthalmol 2001; 16(3): 168-71.
17
Casson RJ, Salmon JF. Combined surgery in the treatment of patients with cataract and primary open-angle glaucoma. J Cataract Refract Surg 2001; 27(11): 1854-63.
18
Cohen JS, Greff LJ, Novack GD, Wind BE. A placebo-controlled, double-masked evaluation of mitomycin C in combined glaucoma and cataract procedures. Ophthalmology 1996; 103(11): 1934-42.
19
Caporossi A, Casprini F, Tosi GM, Balestrazzi A. Long-term results of combined 1-way phacoemulsification, intraocular lens implantation, and trabeculectomy. J Cataract Refract Surg 1999; 25(12): 1641-5.
20
Khandelwal R, Raje D, Rathi A, Agashe A, Majumdar M, Khandelwal R. Surgical outcome of safe surgery system trabeculectomy combined with cataract extraction. Eye 2015; 29(3): 363-70.
21
Mamalis N, Lohner S, Rand AN, Crandall AS. Combined phacoemulsification, intraocular lens implantation, and trabeculectomy. J Cataract Refract Surg 1996; 22(4): 467-73.
22
Henderson H, Ezra E, Murdoch I. Early postoperative trabeculectomy leakage: incidence, time course, severity, and impact on surgical outcome. Br J Ophthalmol 2004; 88(5): 626-9.
23
Sathyan P, Singh G, Eong K-GA, Raman GV, Sathyan P, Prashanth S. Suprachoroidal hemorrhage following removal of releasable suture after combined phacoemulsification–trabeculectomy. J Cataract Refract Surg 2007; 33(6): 1104-5.
24
Tezel G, Kolker AE, Kass MA, Wax MB. Late removal of releasable sutures after trabeculectomy or combined trabeculectomy with cataract extraction supplemented with antifibrotics. J glaucoma 1998; 7(2): 75-81.
25
ORIGINAL_ARTICLE
The Relationship of Uterine Artery Doppler Velocimetry Findings and Hemoglobin Concentration with Pregnancy Outcomes in Pre-eclampsia
Abstract Background: Epidemiologic studies have shown the relationship of maternal hemoglobin level and abnormal findings in uterine Doppler sonography with pregnancy- related complications. In this study, we evaluated the relationship of uterine artery Doppler velocimetry findings and hemoglobin level with the outcomes of pregnancy in women with preeclampsia and healthy women. Methods: In this prospective study performed from September 2013 to September 2014, 50 patients with Preeclampsia in the third trimester (more than 28 weeks) referred to Afzalipour Hospital, Kerman/ Iran and 50 healthy pregnant women who attended the perinatology clinic for prenatal care, were randomly selected. The results of uterine artery Doppler, hemoglobin concentration and outcome of pregnancy were compared between the two groups. Results:Twenty nine patients (51%) with preeclampsia and 17 patients (34%) in the control group had abnormal Doppler findings. In both groups, birth weight was lower in women with abnormal Dopller findings compared to the women who had normal sonography findings (p=0.024 and p=0.008, respectively); furthermore, in both groups, gestational age at birth time was lower in women with abnormal sonography findings (p=0.044 and p=0.012, respectively). The average hemoglobin concentration was not statistically different between the two groups and abnormal Doppler findings showed no significant relationship with the mean concentration of hemoglobin in none of the two groups. Conclusion: This study showed that abnormal findings in Doppler of the uterine artery are associated with adverse pregnancy outcomes such as low birth weight and premature births and the coexistence of preeclampsia is associated with worse pregnancy outcomes.
https://jkmu.kmu.ac.ir/article_46776_d2fbc68b23f63c85c49f8459250f6e7c.pdf
2017-03-01
125
131
Doppler sonograghy
Hemoglobin
Perinatal outcome
Pregnancy
preeclampsia
fatemeh
mirzaie
mirzaiefatemeh46@gmail.com
1
Associate Professor, Department of Ob. & Gyn., Afzalipoor School of Medicine & Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Hajar
Vatankhah
2
Gynecologist, Department of Ob. & Gyn, NikNafs Hospital , Rafsanjan University of Medical Sciences, Rafsanjan , Iran
AUTHOR
Peyman
Arasteh
3
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Shahabi A, Wilson ML, Lewinger JP, Goodwin TM, Stern MC, Ingles SA. Genetic admixture and risk of hypertensive disorders of pregnancy among Latinas in Los Angeles County. Epidemiology 2013; 24(2): 285-94.
1
Ghi T, Youssef A, Piva M, Contro E, Segata M, Guasina F, et al. The prognostic role of uterine artery Doppler studies in patients with late-onset preeclampsia. AmJ Obstet Gynecol 2009; 201(1): 36. e1-. e5.
2
Hladunewich M, Karumanchi SA, Lafayette R. Pathophysiology of the clinical manifestations of preeclampsia. Clinical journal of the American Society of Nephrology : CJASN 2007; 2(3): 543-9.
3
Maged AM, Elnassery N, Fouad M, Abdelhafiz A, Al Mostafa W. Third -trimester uterine artery Doppler measurement and maternal postpartum outcome among patients with severe pre-eclampsia. Int J Gyn Obtet 2015; 131(1): 49-53.
4
Shwarzman P, Waintraub A, Frieger M, Bashiri A, Mazor M , Hershkovitz R.Third trimester abnormal uterine artery Doppler findings are associated with adverse pregnancy outcomes.J Ultrasound Med 2013 ; 32 (12):2107-2113.
5
Hwang HS, Kim YH, Kwon JY, Park YW. Uterine and umbilical artery Doppler velocimetry as a predictor for adverse pregnancy outcomes in pregnant women with anemia. J perinat Med 2010; 38(5): 467-71.
6
Gonzales GF, Tapia V, Gasco M,Carrillo CE.Maternal hemoglobin concentration and adverse pregnancy outcomes at low and moderate altitudes in Peru.J Matern Fetal Neonatal Med ; 2012; 25 (7): 1105-1110.
7
Cordina M, Bhatti S, Fernandez M, Syngelakki A, Kypros H, Nicolaides KH, Kametas NA.Maternal .hemoglobin at 27-29 weeks gestation and severity of prreclampsia. JMatern Fetal Neonatal Med2015; 28 (13): 1-6.
8
Gomez O, Figueras F, Fernandez S, Bennaser M, Martinez JM, Puerto B, et al. Reference ranges for uterine artery mean pulsality index at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 2008; 32 (2): 126-32.
9
Eser A, Zulfikaroglu E, Eserdag S, Kilic S, Danisman N. Predictive value of middle cerebral artery to uterine artery pulsatility index ratio in preeclampsia. Arch Gynecol Obstet 2011; 284(2): 307-11.
10
Herraiz I, Escribano D, Gómez‐Arriaga P, Herníndez‐García J, Herraiz MA, Galindo A. Predictive value of sequential models of uterine artery Doppler in pregnancies at high risk for pre‐eclampsia. Ultrasound Obstet Gynecol 2012; 40(1): 68-74.
11
Myatt L, Clifton RG, Roberts JM, Spong CY, Hauth JC, Varner MW, et al. The utility of uterine artery Doppler velocimetry in prediction of preeclampsia in a low-risk population. Obstet gynecol 2012; 120(4): 815-22.
12
Pinto de Melo BC, Ramos de Amorim MM, Katz L, Coutinho I, Veríssimo G. Uterine artery Doppler in the third trimester of pregnancy and postnatal outcome of patients with severe preeclampsia. Hypertens pregnancy 2010; 29(2): 135-47.
13
Guzin K, Tomruk S, Tuncay YA, Naki M, Sezginsoy S, Zemheri E, et al. The relation of increased uterine artery blood flow resistance and impaired trophoblast invasion in pre-eclamptic pregnancies. ArchGynecolObstet 2005; 272(4): 283-8.
14
Hunkapiller NM, Gasperowicz M, Kapidzic M, Plaks V, Maltepe E, Kitajewski J, et al. A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia. Development 2011; 138(14): 2987-98.
15
Vergani P, Roncaglia N, Andreotti C, Arreghini A, Teruzzi M, Pezzullo JC, et al. Prognostic value of uterine artery Doppler velocimetry in growth-restricted fetuses delivered near term. Am J Obstet Gynecol 2002; 187(4): 932-6.
16
Yip R. Significance of an abnormally low or high hemoglobin concentration during pregnancy: special consideration of iron nutrition. Am J Clin Nut 2000; 72(1 Suppl): 272s-9s.
17
Makuyana D, Mahomed K, Shukusho FD, Majoko F. Liver and kidney function tests in normal and pre-eclamptic gestation--a comparison with non-gestational reference values. Cent Afr J Med 2002; 48(5-6): 55-9.
18
Hershkovitz R, Ohel I, Sheizaf B, Nathan I, Erez O, Sheiner E, et al. Erythropoietin concentration among patients with and without preeclampsia. Arch Gynecol Obstet 2005; 273(3): 140-3.
19
Ventura SJ, Martin JA, Curtin SC, Matthews T, Park MM. Births: final data for 1998: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 2000.
20
ORIGINAL_ARTICLE
The Effects of Rosa canina Fruit Hydro alcoholic Extract on Oxidative Stress, Total Antioxidant Capacity and Haematological Parameters in Diabetic Mice
Abstract Background: Diabetes is a metabolic disorder with adverse effects on haematological parameters level, oxidative stress and antioxidant defence system. This study aimed to investigate the effects of Rosa canina (RC) fruit hydro alcoholic extract on oxidative stress, total antioxidant capacity (TAC) and haematological parameters in diabetic mice. Method: In this study, 96 mice were randomly divided into the four groups (n=24). The control and diabetic groups received normal saline (p.o., 0.2 ml). Also, RC and treatment (diabetes+RC) groups received RC hydro alcoholic extract (p.o., 500 mg/kg). Diabetes was induced by a single dose of streptozotocin (i.p., 200 mg/kg).The study parameters were evaluated on day 10, 20, and 30 after the initiation of experiments. Results: In the second and third sampling days, WBCs, lymphocytes, haemoglobin, RBC, MCV, MCHC, platelets, TAC and weight had a significant reduction (p <0.01) in the diabetic group in comparison to the control group. However, granulocytes, RDW, malondialdehyde (MDA) and glucose in the diabetic group significantly increased compared with the control group (p <0.01). Administration of the extract in the diabetic group significantly increased hemoglobin, MCV, MCHC, platelets, RBC, serum TAC and resulted in significant reduction in RDW and MDA levels in comparison to normal saline received diabetic animals (p <0.01). Conclusion: Based on our results, RC fruit extract has a regulatory role in controlling oxidative stress, serum TAC and hematologic factors in mice model of diabetes.
https://jkmu.kmu.ac.ir/article_46778_afc945fe860a5d29065840d3357ef8c4.pdf
2017-03-01
132
140
oxidative stress
Total Antioxidant Capacity
hematological parameters
Diabetes
Rosa canina
Mice
Freshteh
Rahimi
rahimi@yahoo.com
1
Instructor, Department of Biological Sciences, Higher Education Institute of Rab-Rashid, Tabriz, Iran
AUTHOR
Saeed
Sadigh-Eteghad
saeed.sadigetegad@gmail.com
2
Assistant Professor, Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran
LEAD_AUTHOR
Alireza
Dehnad
dehnad.ar@yahoo.com
3
Associate Professor, Biotechnology Department, East Azerbaijan Research and Education Center for Agriculture and Natural Resources, AREEO, Tabriz, Iran
AUTHOR
Javad
Mahmoudi
mahmoudi2044@gmail.com
4
Assistant Professor, Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran
AUTHOR
Laila
Baradaran
baradaran.l@gmail.com
5
Instructor, Department of Biological Sciences, Higher Education Institute of Rab-Rashid, Tabriz, Iran
AUTHOR
Murugesh K, Yeligar V, Dash DK, Sengupta P, Maiti BC, Maity TK. Antidiabetic, antioxidant and antihyperlipidemic status of heliotropium zeylanicum extract on streptozotocin-induced diabetes in rats. Biol Pharm Bull 2006; 29: 2202-5.
1
Uko EK, Erhabor O, Isaac IZ, Abdulrahaman Y, Adias TC, Sani Y, et al. Some haematological parameters in patients with type-1 diabetes in Sokoto, North Western Nigeria. J Blood Lymph 2013; 3(1): 110-116.
2
Kothari R, Bokariya P. A comparative study of haematological parameters in type i diabetes mellitus patients & healthy young adolescents. Int J Biol Med Res 2012; 3(4): 2429-32.
3
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Papanas N, Symeonidis G, Maltezos E, Mavridis G, Karavageli E, Vosnakidis T, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004; 15(8): 475-8.
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Kodiatte TA, Manikyam UK, Rao SB, Jagadish TM, Reddy M, Lingaiah HK, et al. Mean platelet volume in type 2 diabetes mellitus. J Lab Physicians 2012; 4(1): 5-9.
10
Uemura S, Matsushita H, Li W, Glassford AJ, Asagami T, Lee K-H, et al. Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stress. Circ Res 2001; 88(12): 1291-8.
11
Mohammadi MT, Ramezani Binabaj M, Mirjalili MH, Gaedniaye Jahromi M, Jafari M, Salem F. Effect of atorvastatin on pancreatic oxidative stress in streptozotocin-induced diabetic rat. Iranian Journal of Endocrinology and Metabolism 2013; 15(2): 197-204.
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Kaneto H, Kawamori D, Matsuoka TA, Kajimoto Y, Yamasaki Y. Oxidative stress and pancreatic β-cell dysfunction. Am J Ther 2005; 12(6): 529-33.
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Pazdro R, Burgess JR. The role of vitamin e and oxidative stress in diabetes complications. Mech Ageing Dev 2010; 131(4): 276-86.
14
Coruh N, Celep AS, Özgökçe F. Antioxidant properties of prangos ferulacea (L.) lindl., chaerophyllum macropodum Boiss. And Heracleum persicum desf. From apiaceae family used as food in eastern anatolia and their inhibitory effects on glutathione-S-transferase. Food Chem 2007; 100(3): 1237-42.
15
Sadigh-Eteghad S, khayat-Nuri H, Abadi N, Ghavami S, Golabi M, Shanebandi D. Synergetic effects of oral administration of levamisole and echinacea purpurea on immune response in wistar rat. Res vet sci 2011; 91(1): 82-5.
16
Hamidi S, Vaez H, Asgharian P. Rosa canina as an adjunctive treatment of asthma: A hypothesis. Adv Biosci Clin Med 2015; 3(1): 48-52.
17
El-Masry AA: Effect of some medicinal plant oils on some physiological parameters in streptozotocin induced diabetic rat. Wudpecker J Medicin Plants 2011; 2: 22-35.
18
Dutta M, Biswas UK, Chakraborty R, Banerjee P, Kumar A, Raychaudhuri U. Enhanced antioxidant enzymea ctivity in tissues and reduced total oxidative stress in plasma by the effect of swietenia macrophylla king seeds in type ii diabetes rats. Inter J Herb Med 2014; 1(6): 31-6.
19
Colomeu TC, Figueiredo D, Cazarin CB, Schumacher NS, Marostica MR, MelettiLM, et al. Antioxidant and anti-diabetic potential of passiflora alata curtis aqueous leaves extract in type 1 diabetes mellitus (nod-mice). Int Immunopharmacol 2014; 18(1): 106-15.
20
Demir F, Özcan M. Chemical and technological properties of rose (rosa canina L.) fruits grown wild in turkey. J Food Eng 2001; 47(4): 333-36.
21
Kilicgun H, Altiner D. Correlation between antioxidant effect mechanisms and polyphenol content of rosa canina. Pharmacogn Mag 2010; 6(23): 238-41.
22
Chrubasik C, Roufogalis BD, Müller‐Ladner U, Chrubasik S. A systematic review on the rosa canina effect and efficacy profiles. Phytother Res 2008; 22(6): 725-33.
23
Tayefi‐Nasrabadi H, Sadigh‐Eteghad S, Aghdam Z. The effects of the hydroalcohol extract of rosa canina L. Fruit on experimentally nephrolithiasic wistar rats. Phytother Res 2012; 26(1): 78-85.
24
Kirkeskov B, Christensen R, Bügel S, Bliddal H, Danneskiold-Samsøe B, Christensen LP, et al. The effects of rose hip (rosa canina) on plasma antioxidative activity and c-reactive protein in patients with rheumatoid arthritis and normal controls: A prospective cohort study. Phytomedicine 2011; 18(11): 953-8.
25
Sadigh-Eteghad S, Tayefi-Nasrabadi H, Aghdam Z, Zarredar H, Shanehbandi D, Khayyat L, et al. Rosa canina L. Fruit hydro-alcoholic extract effects on some immunological and biochemical parameters in rats. BioImpacts 2011; 1(4): 219-24.
26
Orhan N, Aslan M, Hosbas S, Deliorman OD. Antidiabetic effect and antioxidant potential of rosa canina fruits. Pharmacogn Mag 2009; 5(20): 309-15.
27
Deeds MC, Anderson JM, Armstrong AS, Gastineau DA, Hiddinga HJ, Jahangir A, et al. Single dose streptozotocin-induced diabetes: Considerations for study design in islet transplantation models. Lab Anim 2011; 45(3): 131-40.
28
Gireesh G, Thomas SK, Joseph B, Paulose C. Antihyperglycemic and insulin secretory activity of costus pictus leaf extract in streptozotocin induced diabetic rats and in in vitro pancreatic islet culture. J Ethnopharmacol 2009; 123(3): 470-4.
29
Malek Mahdavi A, Mahdavi R, Kolahi S, Zemestani M, Vatankhah AM. L-carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis. Nutr Res 2015; 35(8): 707-15.
30
Saliu J, Elekofehinti O, Komolafe K, Oboh G. Effects of some green leafy vegetables on the haematological parameters of diabetic rats. J Nat Prod Plant Resour 2012; 2(4): 482-5.
31
Edet AE, Patrick EE, Olorunfemi A. Hematological parameters of alloxan-induced diabetic rats treated with ethanol extracts and fractions of nauclea lafiloia leaf. Eur Sci J 2013; 9(27): 203-210.
32
Aladodo RA, Muhammad NO, Balogun EA. Effects of aqueous root extract of jatropha curcas on hyperglycaemic and haematological indices in alloxan-induced diabetic rats. Fountain J Nat App Sci 2013; 2(1): 52-8.
33
Longe A, Momoh J, Adepoju P. Effects of cinnamon aqueous extract on blood glucose levell, liver biomarker enzymes, hematological and lipid profile parameters in aloxan-induced diabetic male albino rats. Eur Sci J 2015; 1: 418-26.
34
Kanter M, Coskun O, Korkmaz A, Oter S. Effects of nigella sativa on oxidative stress and β‐cell damage in streptozotocin‐induced diabetic rats. Anat Rec A Discov Mol Cell Evol Biol 2004; 279(1): 685-91.
35
Ugochukwu N, Babady N, Cobourne M, Gasset S. The effect of gongronema latifolium extracts on serum lipid profile and oxidative stress in hepatocytes of diabetic rats. J Biosci 2003; 28(1): 1-5.
36
Fallahi F, Roghani M, Bagheri A. Time-dependent hypoglycemic and hypolipidemic effect of allium ascalonicum L. Feeding in diabetic rats. J Babol Univ Med Sci 2010; 12(1): 16-23.
37
Khalili M, Vaez Mahdavi M, Kiasalari Z, Ansari F. The effect of long-term consumption of commiphora mukul feeding on the serum levels of glucose and lipids of diabetic rats. Iranian Journal of Endocrinology and Metabolism 2009; 11(1): 71-7.
38
Morshedi A, Dashti M, Rafati A, Salami A, Mosaddegh M. The chronic effect of kombucha tea consumption on weight loss in diabetic rats. Journal of Medicinal Plants 2006; 5: 42-7.
39
ORIGINAL_ARTICLE
Anatomical Evaluation of Renal Arteries and Veins in Kidney Donors by CT Angiography
AbstractBackground: Renal transplantation (RT) is the transplantation of a kidney into a patient with end-stage renal disease and has become the treatment of choice for most patients with end-stage renal disease. The knowledge of renal vascular variations is of a great importance for the surgeons who approach the kidneys from the retroperitoneal or laparoscopic route for renal transplants. The aim of this study was to detect renal vascular variations of kidney donors in Kerman by using CT angiogram.Methods: This cross-sectional study examined the CT angiograms of all kidney donors referred to the Radiology Ward of Shafa Medical center affiliated to Kerman University of Medical Sciences from 2010 to 2012.Results: The results of CT angiograms of 344 kidney donors were as follow: Right Renal Arteries: 236 cases with one artery; 97 cases with two arteries; 9 cases with three arteries; and one case with four arteries Left Renal Arteries: 225 cases with one artery; 103 cases with two arteries; and 16 cases with three arteries Right Renal Veins: 277 cases with one vein and 12 cases with two veins Left Renal Veins: 279 cases with one vein and 10 cases with two veins.Conclusion: There is no significant difference between our results and those of previous studies. In more than 30% of cases, our findings were associated with other incidental findings.
https://jkmu.kmu.ac.ir/article_46781_c3d160f9b6bc2caaf8350561cd1e7a3d.pdf
2017-03-01
141
146
CT angiogram
renal transplantation
Kidney
Renal artery
Renal vein
Mohammad
Saba
1
Assistant Professor of Radiology, Department of Radiology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Hossein Ali
Ebrahimi meimand
hebrahimi@kmu.ac.ir
2
Professor of Neurology, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Ali
Shahrabi
3
Resident of Radiology, Department of Radiology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, iran
AUTHOR
Aazam
Dehghani
4
Master of Biostatistics, kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Zadeh KA. Roman slave. 3rd ed., Tehran, Heydari press; 2009.
1
Zahedi F, Fazel I, Larijani B. An overview of organ transplantation in Iran over three decades: with special focus on renal transplantation. Iranian Journal of Public Health 2009; 38(Suppl. 1):138-49.
2
AkhlaqePezeshki be–enzemamemokhtasaryaztarikhpezeshki. Tehran, Sepehr press; 1991 [In Persian].
3
Starzl TE. Peter Brian Medawar: father of transplantation. Journal of the American College of Surgeons 1995; 180(3):332.
4
Ghods AJ. Renal transplantation in Iran. Nephrol Dial Transplant 2002; 17(2):222-8.
5
Broumand B. Living donors: the Iran experience. Nephrol Dial Transplant 1997; 12(9):1830-1.
6
Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341(23):1725-30
7
Fernandes RMP,Conte FHP, Favorito LA, Abidu-Figueiredo M, Babinski MA. Triple right renal vein: an uncommon variation. Int J Morphol 2005; 23(3):231-3.
8
Sutton D. Text book of radiology and Imaging. 7th ed., London, Churchill Livingstone 2003.
9
Helms C, Brant WE. Fundamentals of diagnostic radiology. 7th ed.,Edingburgh, Churchill Livingstone, 2007; pp 982-6
10
Engelken F, Friedersdorff F, Fuller T, Magheli A, Budde K, Halleck F, et al. Pre-operative assessment of living renal transplant donors with state-of-the-art imaging modalities: computed tomography angiography versus magnetic resonance angiography in 118 patients. World J Urol 2013; 31(4):983-90.
11
Razavizadeh RT, Tabasi KT,Rana TM. Pre-operative evaluation of living kidney donors using computerized tomographic angiography (CTA) and conventional angiography: comparison with intraoperative findings. Saudi J Kidney Dis Transpl 2012; 23(3):471-6.
12
Kawamoto S, Montgomery RA, Lawler LP, Horton KM, Fishman EK. Multidetector CT angiography for preoperative evaluation of living laparoscopic kidney donors. American Journal of Roentgenology 2003;180(6):1633-
13
Boijsen E. Renal angiography: techniques and hazards; anatomic and physiologic considerations. Vascular and Interventional radiology. 1997; 4:1101-31.
14
Khamanarong K, Prachaney P, Utraravichien A, Tong‐Un T, Sripaoraya K. Anatomy of renal arterial supply. Clinical anatomy 2004; 17(4):334-6.
15
Behar JV, Nelson RC, Zidar JP, DeLong DM, Smith TP. Thin-section multidetector CT angiography of renal artery stents. American Journal of Roentgenology 2002; 178(5):1155-9.
16
Scatarige JC, Horton KM, Ratner LE, Fishman EK. Left adrenal vein localization by 3D real-time volume-rendering CTA before laparoscopic nephrectomy in living renal donors. Abdom Imaging 2001; 26(5):553-6.
17
Rydberg J, Kopecky KK, Tann M, Persohn SA, Leapman SB, Filo RS, et al. Evaluation of Prospective Living Renal Donors for Laparoscopic Nephrectomy with Multisection CT: The Marriage of Minimally Invasive Imaging with Minimally Invasive Surgery 1. Radiographics 2001; 21(suppl_1):S223-S36.
18
Patil UD, Ragavan A, Murthy K, Shankar R, Bastani B, Ballal SH. Helical CT angiography in evaluation of live kidney donors. Nephrol Dial Transplant 2001; 16(9):1900-4.
19
Chai JW, Lee W, Yin YH, Jae HJ, Chung JW, Kim HH, et al. CT angiography for living kidney donors: accuracy, cause of misinterpretation and prevalence of variation. Korean J Radiol 2008; 9(4):333-9.
20
Sattar A, Naeem S, Ali A, Akhtar M, Rizvi A, Naqvi A. Evaluation of Number of Renal Arteries in Live Related Renal Donors by CT Angiography and Conventional Angiography. International Journal of Endorsing Health Science Research 2014; 2 (1):1-15.
21
Alam A, Chander BN, Joshi DP. 3-D spiral computerised tomographic angiography in evaluation of potential renal donors. Med J Armed Forces India 2003; 59(3):205-8.
22
Kulkarni S, Emre S, Arvelakis A, Asch W, Bia M, Formica R, et al. Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy. Clin Transplant 2011; 25(1):77-82.
23
Platt JF, Ellis JH, Korobkin M, Reige K. Helical CT evaluation of potential kidney donors: findings in 154 subjects. AJR American journal of Roentgenology1997; 169(5):1325-30.
24
Shashikala P, Anjali W, Anshuman N, Jayshree D. A case report: double renal arteries. International Journal of Anatomical Variations 2012; 5:22-4.
25
Laugharne M, Haslam E, Archer L, Jones L, Mitchell D, Loveday E, et al. Multidetector CT angiography in live donor renal transplantation: experience from 156 consecutive cases at a single centre. TransplInt 2007; 20(2):156-66.
26
Saba M, Ebrahimi H-A, Ahmadipour H, Taziki M-A. Evaluation of Incidental Findings on Lumbosacral MRI in Patients with Low Back Pain. Journal of Kerman University of Medical Sciences 2015; 22(4):433-9 [In Persian].
27
ORIGINAL_ARTICLE
Photocatalytic removal of o-chlorophenol by Using a Mixture of Modified Fly Ash and TiO2 Nanoparticles
Abstract Background: Photocatalytic process is used as a suitable method for o-chlorophenol removal. In this study, the efficiency of a mixture of modified fly ash and TiO2 nanoparticles in photocatalytic removal of o-chlorophenol was evaluated. Methods: After acid washing of fly ash, the absorbent was oxidized with potassium permanganate. Then, the substrate mixture of modified fly ash and TiO2 nanoparticles was used for photocatalytic decomposition of o-chlorophenol. Results: The percentage of carbon increased from 77.94% to 86.52% after acid washing of fly ash and absorption efficiency increased from 58.8% up to 83.3%. During the oxidation of acid washed fly ash, absorption efficiency reached to 93.27%. Photocatalytic removal efficiency of o-chlorophenol by mixture of modified fly ash and TiO2 increased to 98.9%. Photocatalytic removal efficiency of o-chlorophenol by TiO2/UV and without use of fly ash was 78.7%. Conclusion: Industrial application of this method recommended because of the simple modification, high efficiency removal and prevention of environment pollution.
https://jkmu.kmu.ac.ir/article_46783_a9c33433c10748fdb0c14b0682667374.pdf
2017-03-01
147
158
Modified absorbent
Fly ash
O-chlorophenol
TiO2 nanoparticles
Photocatalytic
Mixture substance
Mohammad
Malakootian
m.malakootian@yahoo.com
1
Professor, Environmental Health Engineering Research Center & Department of Environmental Health, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Alireza
Mesdaghinia
amesdaghinia@tums.ac.ir
2
Professor, Department of Environmental Health Engineering, School of Public Health & Water Quality Research Centre, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Shima
Rezaei
sh_rezaey@yahoo.com
3
MSc, Environmental Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
LEAD_AUTHOR
Khanikar N, Bhattacharyya KG. Cu(II)-kaolinite and Cu(II)-montmorillonite as catalysts for wet oxidative degradation of 2-chlorophenol, 4-chlorophenol and 2,4-dichlorophenol. Chemical Engineering Journal. 2013; 233(0):88-97.
1
Fattahi N, Assadi Y, Hosseini MRM, Jahromi EZ. Determination of chlorophenols in water samples using simultaneous dispersive liquid–liquid microextraction and derivatization followed by gas chromatography-electron-capture detection. Journal of Chromatography A. 2007; 1157(1-2):23-9.
2
Sun D, Zhang H. Electrochemical determination of 2-chlorophenol using an acetylene black film modified glassy carbon electrode. Water res. 2006; 40(16): 3069-74.
3
Andini S, Cioffi R, Colangelo F, Montagnaro F, Santoro L. Adsorption of chlorophenol, chloroaniline and methylene blue on fuel oil fly ash. J hazard mater 2008; 157(2-3):599-604.
4
Lin S.H, Pan C.L, Leu H.G. Equilibrium and mass transfer characteristics of 2-chlorophenol removal from aqueous solution by liquid membrane. Chemical Engineering Journal 2002; 87(2):163-9.
5
Mangrulkar PA, Kamble SP, Meshram J, Rayalu SS. Adsorption of phenol and o-chlorophenol by mesoporous MCM-41. J Hazard Mater 2008; 160(2-3): 414-21.
6
Nadavala SK, Swayampakula K, Boddu VM, Abburi K. Biosorption of phenol and o-chlorophenol from aqueous solutions on to chitosan–calcium alginate blended beads. J Hazard Mater 2009; 162(1): 482-9.
7
Sarkar M, Acharya PK. Use of fly ash for the removal of phenol and its analogues from contaminated water. Waste Manag 2006; 26(6): 559-70.
8
Altunlu M, Yapar S. Effect of OH−/Al3+ and Al3+/clay ratios on the adsorption properties of Al-pillared bentonites. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2007; 306(1-3): 88-94.
9
Tu Y, Xiong Y, Tian S, Kong L, Descorme C. Catalytic wet air oxidation of 2-chlorophenol over sewage sludge-derived carbon-based catalysts. J hazard mater 2014; 276: 88-96.
10
Yang B, Zhang J, Zhang Y, Deng S, Yu G, Wu J, et al. Promoting effect of EDTA on catalytic activity of highly stable Al–Ni bimetal alloy for dechlorination of 2-chlorophenol. Chemical Engineering Journal 2014; 250: 222-9.
11
Bertelli M, Selli E. Reaction paths and efficiency of photocatalysis on TiO2 and of H2O2 photolysis in the degradation of 2-chlorophenol. J Hazard Mater 2006; 138(1): 46-52.
12
Rezaee A, Pourtaghi G, Khavanin A, Saraf Mamoori R, Hajizadeh E, Vali pour F. Elimination of toluene by Application of ultraviolet irradiation on TiO2 nano particles photocatalyst. Journal of Military Medicine2007; 9(3): 217-22.
13
Wasu L, Virote B. Enhancing the photocatalytic activity of TiO2 co-doping of graphene Fe3+ ions for formaldehyde removal. Journal of Environmental Management 2013; 127:142-9.
14
Visa M, Duta A. TiO2/fly ash novel substrate for simultaneous removal of heavy metals and surfactants. Chemical Engineering Journal. 2013; 223(0):860-8.
15
Kuncoro EP, Fahmi MZ. Removal of Hg and Pb in aqueous solution using coal fly ash adsorbent. Procedia Earth and Planetary Science. 2013; 6:377-82.
16
Anbia M, Amirmahmoodi S. Adsorption of phenolic compounds from aqueous solutions using functionalized SBA-15 as a nano-sorbent. Scientia Iranica 2011; 18(3):446-52.
17
Kazemian H, Ghaffari Kashani T, Noorian MS. Synthesis and characterization of zeolite A, using fly ash of the Iran Ferrosilice Company and investigating its ion-exchange properties. Iranian society of crystallography and mineralogy. 2005; 13(2):329-36.
18
Malarvizhi TS, Santhi T, Manonmani S. A Comparative Study of Modified Lignite Fly Ash for the Adsorption of Nickel from Aqueous Solution by Column and Batch Mode Study. Research Journal of Chemical Sciences 2013; 3(2): 44-53.
19
Tiwari M, Sahu SK, Bhangare RC, Ajmal PY, Pandit GG. Elemental characterization of coal, fly ash, and bottom ash using an energy dispersive X-ray fluorescence technique. Appl Radiat Isot 2014; 90: 53-7.
20
Malakootian M, Almasi A, Hossaini H. Pb and Co removal from paint industries effluent using wood ash. International Journal of Environmental Science & Technology 2008; 5(2):217-22.
21
Malakootian M, Asadi M. Efficiency of fenton oxidation process in removal of phenol in aqueous solutions. Journal of Water and Wastewater 2011; 22(3): 46-52
22
Malakootian M, Mansuri F. Hexavalent chromium removal by titanium dioxide photocatalytic reduction and the effect of phenol and humic acid on its removal efficiency. International Journal of Environmental Health Engineering 2015; 4(1): 19.
23
Malakootian M, Mesdaghinia A, Rezaei S. Evaluation of removal efficiency of 2-chlorophenol in aquatic environments by modified fly ash. 2015; 2(4): 179-85.
24
Malakootian M, Mesdaghinia A, Rezaei S. The Photocatalytic Removal of Ortho Chlorophenol from Aqueous Solution Using Modified Fly Ash-Titanium Dioxide. Journal of Water and Wastewater 2016; 27(2):14-21.
25
Malakootian M, Rezaee S, Nasiri A.R, Amirmahani N. Removal of Methylene Blue Dye from Aqueous Solutions Using Activated Fly Ash from Zarand Power Plant in Kerman. Journal ofwater and wastewater 2015; 3:62-71.
26
Malakoutian M, Mesdaghinia A, Rezaei S. Efficiency of ortho-chlorophenol removal from aqueous solutions using activated Fly Ash of Zarand Fossil Fuel Power Plant. Journal of School of Public Health and Institute of Public Health Research 2014; 12(2): 81-92.
27
Rezaei S, Malakootian M. Kinetics and Isotherm Studies of Methylene Blue Adsorption from Aqueous Solutions by Activated Fly Ash. Toloo-e-Behdasht 2016; 14(6):149-66.
28
Wang S, Wu H. Environmental-benign utilisation of fly ash as low-cost adsorbents. J hazard mater 2006; 136(3): 482-501.
29
Zhang A, Wang N, Zhou J, Jiang P, Liu G. Heterogeneous Fenton-like catalytic removal of p-nitrophenol in water using acid-activated fly ash. J hazard mater 2012; 201:68-73.
30
Luo F, Liu Y, Li X, Xuan Z, Ma J. Biosorption of lead ion by chemically-modified biomass of marine brown algae Laminaria japonica. Chemosphere 2006; 64(7): 1122-7.
31
Tahir H, Sultan M, Akhtar N, Hameed U, Abid T. Application of natural and modified sugar cane bagasse for the removal of dye from aqueous solution. Journal of Saudi Chemical Society 2016; 20(1): S115-S121.
32
Karunakaran C, Gomathisankar P, Manikandan G. Solar photocatalytic detoxification of cyanide by different forms of TiO2. Korean Journal of Chemical Engineering. 2011; 28(5): 1214-20
33
Kashiwakura S, Ohno H, Kumagai Y, Kubo H, Matsubae K, Nagasaka T. Dissolution behavior of selenium from coal fly ash particles for the development of an acid-washing process. Chemosphere 2011; 85(4): 598-602.
34
Li Y, Liu C, Luan Z, Peng X, Zhu C, Chen Z, et al. Phosphate removal from aqueous solutions using raw and activated red mud and fly ash. J Hazard Mater 2006; 137(1): 374-83.
35
Wang S, Boyjoo Y, Choueib A, Zhu ZH. Removal of dyes from aqueous solution using fly ash and red mud. Water Res 2005; 39(1):129-38.
36
Panitchakarn P, Klamrassamee T, Laosiripojana N, Viriya-empikul N, Pavasant P. Synthesis and Testing of Zeolite from Industrial-Waste Coal Fly Ash as Sorbent For Water Adsorption from Ethanol Solution. Engineering Journal 2014; 18(1): 1-12.
37
Rodríguez-Reinoso F. The role of carbon materials in heterogeneous catalysis. Carbon 1998; 36(3): 159-75.
38
Jeon C, Park JY, Yoo YJ. Characteristics of metal removal using carboxylated alginic acid. Water Res 2002; 36(7): 1814-24.
39
Abdel Aal A, Barakat M, Mohamed RM. Electrophoreted Zn–TiO2–ZnO nanocomposite coating films for photocatalytic degradation of 2-chlorophenol. Applied Surface Science 2008; 254(15): 4577-83.
40
Huo P, Yan Y, Li S, Li H, Huang W, Chen S, et al. H2O2 modified surface of TiO2/fly-ash cenospheres and enhanced photocatalytic activity on methylene blue. Desalination 2010; 263(1-3):258-63.
41
Visa M, Duta A. Methyl-orange and cadmium simultaneous removal using fly ash and photo-Fenton systems. J hazard mater 2013; 244: 773-9.
42
Visa M, Carcel RA, Andronic L, Duta A. Advanced treatment of wastewater with methyl orange and heavy metals on TiO2, fly ash and their mixtures. Catalysis Today 2009; 144(1):137-42.
43
Shi Z, Yao S, Sui C. Application of fly ash supported titanium dioxide for phenol photodegradation in aqueous solution. Catalysis Science & Technology. 2011; 1(5): 817-22.
44
Hemmati Borji S, Nasseri S, Nabizadeh R, Mahvi AH, Javadi AH. Photocatalytic degradation of phenol in Aqueous Solutions by Fe(III)-doped TiO2/UV Process. Iran J Health & Environ 2011; 3(4): 369-80.
45
Ghaneian M.T, Ehrampoush M.H, Ghanizadeh Gh, Dehvary M, Abootoraby M, Jasemizad T. Application of Solar Irradiation / K2S2O8 Photochemical Oxidation Process for the Removal of Reactive Blue 19 Dye fromAqueous Solutions. Iran J Health & Environ 2010; 3(2): 165-76.
46
Parastar S, Poureshg Y, Nasseri S, Vosoughi M, Golestanifar H, Hemmati S, et al. Photocatalytic removal of nitrate from aqueous solutions by ZnO/UV process. Journal health and hygiene. 2012; 3(3):54-61.
47
Shirzad Siboni M, Samadi M.T, Rahmani A.R, Khataee A.R, Bordbar M, Samarghandi M.R. Photocatalytic Removal of Hexavalet Chromium and Divalent Nickel fromAqueous Solution by UV Irradiation in the Presence of Titanium Dioxide Vanoparticles. Iranian Journal of Health and Environment 2010; 3(3): 261-70.
48
ORIGINAL_ARTICLE
The Relationship between Hepatitis C Genotypes and Viral Load: a study on hepatitis C patients in Kerman, Iran using Real-time PCR
Abstract Background: Distribution of hepatitis C virus genotypes varies geographically and can be associated with clinical aspects. The virus has six major genotypes and eleven sub-genotypes. According to the recent studies, in hepatitis C patients, treatment duration and ribavirin dosage should be determined based on the type of virus genotype. Because of contradictory results reported in different countries and races, the present study aimed to determine the genotype of hepatitis C and its relationship with viral load in HCV patients in Kerman, Iran. Methods: The study included 106 patients with hepatitis C referred to Dr. Bazrafshani Medical Genetic Lab. in Kerman. Patients’ blood plasma was collected and used for virus genotyping and viral load determination by Real-Time PCR technique. Results: From 106 studied patients, 82 ones were male (77.4%) and 24 ones were female (22.6%). Most frequent genotypes were respectively genotype 3 (55.7%) and genotype 1(44.3%). Viral load in genotype1 was greater than that in genotype 3 (P=0.011). Conclusions: In this study, the predominant genotype was genotype 3. Therefore, treatment strategies should go towards type 3 virus. On the other hand, copy number of genotype 1virus was higher than that of type 3 that should be considered very important in determining the treatment duration in HCV patients.
https://jkmu.kmu.ac.ir/article_46784_362447ac053a07405f8169ebe519dd72.pdf
2017-03-01
159
165
Hepatitis C Virus
Genotype
Viral load
Real-Time PCR
Farideh
Doostan
f_doostan@kmu.ac.ir
1
Assistant Professor, Physiology Research Center, Institute of Basic and Clinical Physiology Sciences & Department of Nutrition, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Marziye Jahanshahi
Jahanshahi
2
MSc. Student, Department of Microbiology, Islamic Azad University, Kerman, Iran
AUTHOR
Farida
Hassanzadeh
3
BSc. in Molecular and Cellular Biology-Genetic, Dr. Bazrafshani Medical Genetic Lab, Kerman, Iran
AUTHOR
Mohammadreza
Bazrafshani
bazr61@yahoo.co.uk
4
Assistant Professor, Department of Medical Genetics, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Vezali E, Aghemo A, Colombo M. A review of the treatment of chronic hepatitis C virus infection in cirrhosis. Clin Ther 2010; 32(13): 2117-38.
1
Irshad M, Ansari MA, Singh A, Nag P, Raghvendra L, Singh S, Badhal SS. Hcv-genotypes: A review on their origin, global status, assay system, pathogenecity and response to treatment. Hepato Gastroenterology 2010; 57(104):1529-38.
2
Keyvani H. Virology of Hepatitis C. Hepatitis B and C Seminar Oct 30 2008. Naft Hospital, Tehran, Iran.
3
Ali Asadi Hashtroudi. Iranian Medical information database.
4
Zali MR, Mayumi M, Raoufi M, Nowroozi A. Hepatitis C virus genotypes in the Islamic Republic of Iran: a preliminary study. East Mediterr Health 2000; 6(2-3):372-7.
5
Samimi-Rad K, Nategh R, Malekzadeh R, Norder H, Magnius L. Molecular epidemiology of hepatitis Cvirus in Iran as reflected by phylogenetic analysis of the NS5B region. J Med Virol2004; 74(2):246-52.
6
Harris KA, Gilham C, Mortimer PP, Teo CG. The most prevalent hepatitis C virus genotypes in England and Wales are 3a and 1a. J Med Virol 1999; 58(2):127-31.
7
Ohno T, Mizokami M, Saleh MG, et al. Usefulness and limitation of phylogenetic analysis for hepatitis C virus core region: application to isolates from Egyptian and Yemeni patients. Arch Virol 1996; 141(6):1101-13.
8
Alavian S, Sali S. A review of the Hepatitis C and how to deal with it. Journal of Medical Council of Islamic Republic of Iran 2000; 18(2): 49-65.
9
Khaliq S, Jahan S, Pervaiz A. Sequence variability of HCV core region: important predictors of HCV induced pattogenesis and viral psduction. Infect genet Evol 2011; 11(3): 543-56.
10
Von Wagner M, Huber M, Berg T, et al. Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Gastroenterology 2005;129(2):522-7.
11
Rodriguez JC, Garcia J, Moya I, Ayelo A, Vazquez N, Sillero C, Royo G. Genetic variability of hepatitis C virus in the health area of Elche (Spain). Correlation between core antigen and viral load. GastroenterolHepatol2003; 26(7): 407-10.
12
Garcia F, Roldan C, Hernandez-Quero J, Bernal MC, Martinez MA, Lopez MA, Piedrola G, Maroto MC. Relationship between viral genotype and viral load in patients with chronic hepatitis C. Eur J ClinMicrobiol Infect Dis 1996; 15(11):884-7.
13
Berg T, Hopf U, Stark K, Baumgarten R, Lobeck H, Schreier E. Distribution of hepatitis C virus genotypes in German patients with chronic hepatitis C: correlation with clinical and virological parameters. J Hepatol 1997; 26(3):484-91.
14
Booth JC, O’grady J, Neuberger J. Clinical guidelines on the management of hepatitis C. Gut, 2001; 49 Suppl 1, I1-21.
15
16- Molaabedin M, Pedarzadeh M. Study of Various HCV Genotypes in Patients Managing by Referral Clinic in Yazd Province. Journal of Medical Sciences Shahid Sadoughi yazd. 2012; 19(6): 784-790.
16
17- Sarvghad M, Bejadi A, Farrokhneia M, Javanian M. Study of hepatitis c virus genotypes in patients with chronic hepatitis in Mashhad]. Med J Mashad Univ Med Sci 2006; 49(93): 309–14.
17
18- Manns MP, Wedemeyer H, Cornberg M. Treating viral hepatitis C: efficacy, side effects, and complications. Gut 2006; 55(9): 1350-9.
18
19- Watanabe K, Yoshioka K, Yano M, Ishigami M, Ukai K, Ito H, Miyata F, Mizutani T, Goto H. Mutations in the nonstructural region 5B of hepatitis C virus genotype 1b: their relation to viral load, response to interferon, and the nonstructural region 5A. J Med Virol 2005; 75(4): 504-12.
19
20- Chakravarti A, Dogra G, Verma V, Srivastava AP. Distribution pattern of HCV genotypes & its association with viral load. Indian J Med Res 2011; 133: 326-31.
20
21- Rodriguez JC, Garcia J, Moya I, Ayelo A, Vazquez N, Sillero C, Royo G. Genetic variability of hepatitis C virus in the health area of Elche (Spain), Correlation between core antigen and viral load. GastroenterolHepatol2003; 26(7): 407-10.
21
22- Singh P, BhatiaV, Pandey M, Shashank M, Tidke P, Jha N, Dutt S. HCV Genotypes Distribution Pattern & ITS Association with Viralloadinindia. International J ournal of Recent Scien Researchs .2013; 4(11): 1682-84.
22
23- Hadinedoushan H, Salmanroghani H, Amirbaigy MK, Akhondi-Meybodi M. Hepatitis C Virus Genotypes and Association with Viral Load in Yazd, Central Province of Iran. Hepat Mon 2014; 14(3): e11705.
23
24- Alizadeh A, Keyvani H, Ranjbar M. Prevalence of hepatitis C virus genotypes in patients with chronic hepatitis C virus in Tehran. Journal of Infectious Diseases and Tropical Medicine. 2008; 13 (40):15-19.
24
ORIGINAL_ARTICLE
Nanoparticles of copper and copper oxides: Synthesis and Determination of antibacterial activity
Abstract In the present study, nanoparticles of copper and copper oxides were synthesized and their antibacterial activity was evaluated and compared with silver nanoparticles. The nanoparticles were synthesized using facile chemical reactions, and then characterized using field emission scanning microscopy. The nanoparticles were stable for at least two weeks. The antibacterial activity of the nanoparticles against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Enterococcusfaecalis and Escherichia coli was investigated based on inhibition zone in disk diffusion assay. The minimum inhibitory concentration and minimum bactericidal concentration of the nanoparticles were also reported. Antibacterial activity of the nanoparticles showed better inhibitory activity against gram positive bacteria.
https://jkmu.kmu.ac.ir/article_46786_b2f86f368c59572e4ed85c92815451cd.pdf
2017-03-01
166
170
copper
Nanoparticles
Antimicrobial activity
Disk diffusion method
Hossein
Heli
heli@sums.ac.ir
1
Assistant Professor, Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
LEAD_AUTHOR
Golamhossein
Tondro
2
Assistant Professor, Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Naghmeh
Sattar ahmady
3
Department of Medical Physics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Rezvan
Dehdari Vais
4
Assistant Professor, Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Hamed
VeisiKahreh
5
Department of Nanomedicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
AUTHOR
Nalwa HS. Encyclopedia of Nanoscience and Nanotechnology. vols 1-10. USA, California: American Scientific Publishers; 2004.
1
Rahi A, Karimian K, Heli H. Nanostructured materials in electro analysis of pharmaceuticals. Anal Biochem 2016; 497, PP 39-47.
2
Rizzello L, Pompa PP. Nano silver-based antibacterial drugs and devices: mechanisms, methodological drawbacks, and guidelines. Chem Soc Rev 2014; 43(5): 1501-18.
3
Pelgrift RY, Friedman AJ. Nanotechnology as a therapeutic tool to combat microbial resistance. Adv Drug Deliv Rev 2013; 65(13-14): 1803-15.
4
Chwalibog A, Sawosz E, Hotowy A, Szeliga J, Mitura S, Mitura K, Grodzik M, Orlowski P, Sokolowska A. Visualization of interaction between inorganic nanoparticles and bacteria or fungi. Int J Nanomedicine 2010; 5: 1085-94.
5
Hajipour MJ, Fromm KM, Ashkarran AA, Jimenez de Aberasturi D, de Larramendi IR, Rojo T, Serpooshan V, Parak WJ, Mahmoudi M. Antibacterial properties of nanoparticles. Trends Biotechnol 2012; 30(10): 499-511.
6
Effenberger F.B, Sulca M.A, Machini M.T, Couto R.A, Kiyohara P.K, Machado G, Rossi L.M. Copper nanoparticles synthesized by thermal decomposition in liquid phase: the influence of capping ligands on the synthesis and bactericidal activity. Journal of Nanoparticle Research 2014; 16: 2588.
7
Jeziorska R, Zielecka M, Gutarowska B, Zakowska Z. High-density polyethylene composites filled with Nano silica containing immobilized Nano silver or Nano copper: thermal, mechanical, and bactericidal properties and morphology and interphase characterization. International Journal of Polymer Science 2014; pp. 1-13.
8
Zain NM, Stapley AG, Shama G. Green synthesis of silver and copper nanoparticles using ascorbic acid and chitosan for antimicrobial applications. Carbohydr Polym 2014; 112: 195-202.
9
Parks G.A. the isoelectric points of solid oxides, solid hydroxides, and aqueous hydroxo complex systems. Chemical Reviews 1965; 65(2): 177-198.
10
ORIGINAL_ARTICLE
Abutment fracture and the technique Used to Remove the fracture portion of the Abutmet: Case Report
Abstract This clinical report presents a case of abutment fracture, due to occlusal overload, occurred with an implant-supported restoration on right mandibular first molar of a female patient. After 6 months of prosthetic reconstruction implants, the patient returned to the clinic due to the loss of implant crown. The fractured fragment of the abutment with the screw protective cotton had remained within the crown of the first molar. A periapical radiograph was taken, which revealed that the base portion of the abutment had remained within the internal hex of the fixture. After removing the abutment screw, the base portion of the fractured abutment did not move due to the close connection and the presence of Morse taper. After applying the methods explained in previous studies, an ultrasonic tip was used counterclockwise to remove the base segment of the implant. The fractured segment of the implant was removed without destroying the implant. Various factors are responsible for the fracture of abutments, including excessive occlusal forces, implant position, implant diameter, inadequate prosthetic adjustment, prosthesis design, metal fatigue, manufacturing defects and galvanic activity. This paper explains the reasons for abutment fractures and a novel technique used to remove the fractured portion.
https://jkmu.kmu.ac.ir/article_46789_068e9c374ca335459739420c13294825.pdf
2017-03-01
171
176
Implant
abutment
Retrieval
fracture
Sina
Safari
1
Assistant Professor, Department of Prosthodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Ali
Eskandarizade
2
Associate professor, kerman Oral Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
fereshteh
sadegh
dr_fereshteh21@yahoo.com
3
Postgraduate Student, Department of Prosthodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
LEAD_AUTHOR
Fereshteh
Hoseini Ghavam
4
Postgraduate Student, Department of Prosthodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Maryam
Hejazi
5
Postgraduate Student, Department of Prosthodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
AUTHOR
Mendonca G, Mendonca DB, Fernandes-Neto AJ, Neves FD. Management of fractured dental implants: a case report. Implant Dent 2009; 18(1):10-16.
1
Al Quran FA, Rashan BA, Al-Dwairi ZN. Management of dental implant fractures: A case history. J Oral Implantol 2009; 35(4):210-14.
2
Alssadi G, Quirynen M, Komerek A, van Steenberghe D. Impact of local and systemic factors on the incidence of oral implant failure, up to abutment connection. J Clin Periodontol 2007; 34(7):610-17.
3
McDermott NE, Chuang SK, Woo VV, Dodson TB. Complications of dental implants: identification, frequency, and associated risk factors. Int J Oral Maxillofac Implants 2003; 18(6):848-55.
4
Gargallo Albiol J, Satorres-Nieto M, Puyuelo Capablo JL, Sanchez Garcés MA, Pi Urgell J, Gay Escoda C. Endosseous dental implant fractures: an analysis of 21 cases. Med Oral Patol Oral Cir Bucal 2008; 13: 124-28.
5
DiPede L, Alhashim A, Vaidyanathan TK, Flinton R. Fracture resistance of soft tissue level implants after cyclic loading and external modification. J Prosthet Dent 2013; 109(1):30-6.
6
Mangano C, Piattelli A, Mortellaro C, Mangano F, Perrotti V, Iezzi G. Evaluation of peri-implant bone response in implants retrieved for fracture after more than 20 years of loading: A case series. J Oral Implantol 2015; 21; 41(4): 414-18.
7
Mish C.E. Dental Implant Prosthetics. 2nd ed., Saint Louis, Elsevier, 2015; pp. 296, 309, 365-366.
8
Bhandari S, Aggarwal N, Bakshi S. Ultrasonic Oscillations for Conservative Retrieval of a Rare Fracture of Implant Healing Abutment. J Oral Implantol 2013; 39(4):475-8.
9
Roe P, Kan JY, Rungcharassaeng K, Won JB. Retrieval of a Fractured Zirconia Implant Abutment Using a clinical report. J Prosthodont 2011; 20(4) 315-18.
10
Balshi TJ. An analysis and management of fractured implants: a clinical report. Int J Oral Maxillofac Implants 1996; 11(5):660-6.
11
Quirynen M, Naert I, Van Steenberghe D. Fixture design and overload influence marginal bone loss and fixture success in the Branemark system. Clin Oral Implants Res 1992; 3(3):104-11.
12
Tagger Green N, Machtei EE, Horowitz J, Peled M. Fracture of dental implants: literature review and report of a case. Implant Dent 2002; 11(2):137-43.
13
Tosun T, Karabuda C, Cuhadaroglu C. Evaluation of sleep bruxism by polysomnographic analysis in patients with dental implants. Int J Oral Maxillofac Implants 2003; 18(2): 286-92.
14
Rangert B, Krogh PH, Langer B, Van Roekel N. Bending overload and implant fracture: a retrospective clinical analysis. Int J Oral Maxillofac Implants 1995; 10(3): 326-33.
15
Conrad HJ, Schulte JK, Vallee MC. Fractures Related To Occlusal Overload With Single Posterior Implants: A Clinical Report. J Prosthet Dent 2008; 99(4): 251-6.
16
Eckert SE, Meraw SJ, Cal E, Ow RK. Analysis of incidence and associated factors with fractured implants: a retrospective study. Int J Oral Maxillofac Implants 2000; 15(5):662-7.
17
Taylor TD, Agar JR, Vogiatzi T. Implant prosthodontics: current perspective and future directions. Int J Oral Maxillofac Implants 2000; 15(1):66-75.
18
Levine RA, Clem DS 3rd, Wilson TG Jr, Higginbottom F, Solnit G. Multicenter Retrospective analysis of the ITI implant system used for single-tooth replacements: Results of loading for 2 or more years. Int J Oral Maxillofac Implants 1999; 14(4): 516-20.
19
Patterson EA, Johns RB. Theoretical analysis of the fatigue of fixture screws in osseointegrated dental implants. Int J Oral Maxillofac Implants 1992; 7(1): 26-33.
20
Thulasidas S, Givan DA, Lemons JE, O'Neal SJ, Ramp LC, Liu PR. Influence of implant angulation on the fracture resistance of zirconia abutments. J Prosthodont 2015; 24(2):127-35.
21