TY - JOUR ID - 16676 TI - Comparison of Salivary Secretory IgA in Caries-free Children and Children with Severe Early Childhood Caries JO - Journal of Kerman University of Medical Sciences JA - JKMU LA - en SN - 1023-9510 AU - POUR eSLAMI, H.R AU - Moshtaghi, GH.R AU - Hori, A AU - SHarifi, M AU - Ziaaddini, H AD - Associate Professor of Pediatric Dentistry, School of Dentistry & Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran AD - Associate Professor of Biochemistry, Afzalipour School of Medicine & Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran AD - Assistant Professor of Pediatric Dentistry, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran AD - Assistant Professor of Pediatric Dentistry, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran AD - Resident of Orthodontics, School of Dentistry, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Y1 - 2010 PY - 2010 VL - 17 IS - 1 SP - 83 EP - 88 KW - immunoglobulins KW - Saliva KW - Dental Caries DO - N2 - Background & Aims: Sever early childhood caries (SECC) is a multifactor common disease that unfortunately there have been a lot of unknown points about it. This study was performed to compare the levels of total S-IgA in children with and without SECC. Methods: In this cross-sectional study 44 children aged 6-24 months were divided into two groups of with SECC (n=20) and without SECC (n=24). The two groups were compared for the concentration of S-IgA assessed with Nephlometric method. The obtained data were analyzed by using t-test and through SPSS 15 software. Results: Mean saliva concentration of S-IgA in children with SECC (18.30 mg/dl) was higher than that in children without SECC (9.46 mg/dl) and this difference was statistically Significant (P<0.05). Conclusion: According to this study, the hypothesis of lower levels of S-IgA in children with SECC might be rejected. UR - https://jkmu.kmu.ac.ir/article_16676.html L1 - https://jkmu.kmu.ac.ir/article_16676_88eca6dd0fd87ba53d371f23f9af8ba2.pdf ER -