Evaluation of Electro Physiological Changes of Sleep among Patients with Supratentorial Ischemic Stroke and Comparison with Control group

Authors

1 Associate Professor of Neurology, Afazalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran Associate Professor, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran

2 Assistant Professor of Neurology, Afazalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran Assistant Professor, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran

3 Associate Professor of Neurology, Afazalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran Associate Professor, Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran

4 Neurologist

Abstract

Background & Aims: Sleep disorders are common complains in patients with cerebral stroke; studies on these issues are limited. We aimed to evaluate the sleep changes in patients with supratentorial ischemic stroke. Methods: In this cross sectional study, 38 patients (19 patients in supratentorial ischemic stroke group and 19 people in control group) were evaluated. Total sleep time, sleep efficacy, percent of stage 2 of Non-rapid eye movement (NREM) sleep, Rapid eye movement (REM) latency, sleep spindle, sleep intensity, and saw tooth wave were evaluated by Electroencephalogram (EEG) monitoring during sleep in both groups and were compared between them. Results: Patients in supratentorial ischemic stroke group had less sleep efficacy (P < 0.01), shorter stage 2 of NREM sleep (P < 0.01), greater REM latency (P < 0.05) and lesser sleep spindles (P < 0.01) in comparison with those in control group. There was no significant difference in saw tooth wave between two groups. Significant differences observed between two hemisphere in sleep density (P = 0.01) and REM latency (P < 0.05). Conclusion: Supratentorial ischemic stroke accompanied with sleep changes on EEG monitoring. These changes were seen in both REM and NREM periods and showed that supratentorial structures are involved in sleep–awake process.

Keywords