A Case Report of Newborn with Thrombocytosis Born to an Opioid-addict Mother

Document Type: Case Report


1 General practitioner

2 Assistant professor of pediatrics, Medical Center of Pediatrics diseases, Tehran, Iran

3 Assistant Professor, Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran


Neonatal thrombocytosis is a very rare phenomenon in infants born to addict mothers. It can be due to opioids withdrawal and occurs a few days after delivery. The etiology is unknown and it is eradicated gradually without any complication. The reported neonate was born to a heroin addict mother who has used methadone during pregnancy. The neonate was admitted in 14th day of life in neonatal intensive care unit (NICU) with the diagnosis of withdrawal syndrome and supportive care was administered for him. Thrombocytosis was detected in routine lab tests. There was not any reason for it except his mother’s addiction. The platelet count was 1,168,000 in the first day and decreased gradually during 28 days to 739,000. There was not any complication and no special treatment was administered. This case indicates that thrombocytosis may happen as a part of neonatal abstinence syndrome and is eradicated without any complication.