A Case Report of Transgrediant Palmoplantar Keratoderma (Mal de Meleda)

Document Type: Case Report

Authors

1 Dermatologist, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

2 Resident of Dermatology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

3 Professor of Dermatology, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Abstract

Mal de Meleda is a rare autosomal recessive transgredient keratoderma .Onset is in early childhood, and the development of hyperkeratosis is preceded by erythema. Patches of waxy ivory-yellow hyperkeratosis extend across the whole palms and soles, and on to the dorsal surfaces of hands and feet. Similar lesions of knees and elbows may develop. We describe an 18 year old man with the diagnosis of Mal de Meleda who shows the typical Gloves and Socks presentation, hyperhidrosis and fibrotic bands (Pseudoainhum) in many of the fingers and toes.

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