Aggressive Fibromatosis of Parapharyngeal Space: a rare case report

Document Type: Case Report


1 Associate Professore of E.N.T, School of Medicine, Kerman University of Medical Sciences and Health Services , Kerman, Iran.

2 Assistant Professor of Pathology, School of Medicine, Kerman University of Medical Sciences and Health Services, Kerman, Iran.


Aggressive fibromatosis also known as extra abdominal desmoid tumor is an uncommon benign tumor of
soft tissue origin with fibroblastic proliferationSince the tumor is locally aggressive, the lesion may be
misdiagnosed as low -grade fibrosarcoms. It accounts for 0.03% - 0.1% of all body tumors and 3% of all soft
tissue tumors. Only 10% to 15% of these lesions occur in head and neck, usually in the supraclavicular fossa.
Occurrence in parapharyngeal space is rare and only two cases of aggressive fibromatosis in the
parapharyngeal space and two other cases in ear, nose and throat have been reported so far. The selective
treatment is surgical resection. The rate of recurrence in head and neck is 19-70%. In the case of recurrence
radiotherapy has been suggested.
In this paper a new case of aggressive fibromatosis tumor in parapharyngeal space in a 35-year old man is
reported in whom surgical resection was performed through parapharyngeal transcervical with preservation
of local organs and the pathology report confirmed the diagnosis of aggressive fibromatosis.