1Assistant Professor of Periodontology, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
2Professor of Periodontology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Introduction: Most periodontal treatments aim to reduce probing depths and maintaining or improving attachment. One of these techniques for treatment of intrabony defects is guided tissue regeneration (GTR). The aim of this study was to compare one-wall intrabony defects treatment with GTR and flap debridement alone. Methods: Eight patients aged 32-43 years participated in this randomized controlled clinical trial. In the test side, a collagen membrane was used after flap/debridement but in the control side, only flap/debridement was performed. Clinical treatment outcomes were evaluated 6 months after surgery. Paired t-test was used for analyzing the data. Results: A mean reduction in pocket depth value of 5.5 mm and mean bone fill of 2.75 mm occurred in the test group. A mean reduction in pocket depth value of 5.7 mm and mean bone fill of 1.5 mm occurred in the control group. The difference between the two treatments was statistically significant in terms of bone fill (P = 0.01) and reduction in hemiseptal defect depth (P = 0.00). Conclusion: Based on the results of this study using barrier membranes produced better clinical parameters of one-wall intrabony defects and proved to be superior to access flap alone.