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Hashemian, M., Aflatoonian, M., Aflatoonian, B., Akbari, M. (2017). The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer. Journal of Kerman University of Medical Sciences, 24(2), 111-117.
Morteza Hashemian; Mohammad Reza Aflatoonian; Behnaz Aflatoonian; Mohammad Esmaeil Akbari. "The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer". Journal of Kerman University of Medical Sciences, 24, 2, 2017, 111-117.
Hashemian, M., Aflatoonian, M., Aflatoonian, B., Akbari, M. (2017). 'The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer', Journal of Kerman University of Medical Sciences, 24(2), pp. 111-117.
Hashemian, M., Aflatoonian, M., Aflatoonian, B., Akbari, M. The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer. Journal of Kerman University of Medical Sciences, 2017; 24(2): 111-117.

The Relationship of gravidity with the Frequency of Removed Lymph Nodes in Mastectomy and Involved Lymph Nodes after the Surgery in Women with Breast Cancer

Article 2, Volume 24, Issue 2, March and April 2017, Page 111-117  XML PDF (1.73 MB)
Document Type: Original Article
Authors
Morteza Hashemian1; Mohammad Reza Aflatoonian2; Behnaz Aflatoonian3; Mohammad Esmaeil Akbari 4
1Assistant Professor, Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran
2Assistant Professor, Bam University of Medical Sciences, Bam, Iran
3Researcher, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran
4Professor of Endocrine surgery, Cancer Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran
Abstract
Abstract

Background: Breast cancer is the most common fatal cancer among women worldwide and it has an increasing rate in Iranian women. The aim of this study was to determine the relationship of gravidity with removed lymph nodes and involved lymph nodes after mastectomy surgery in women with breast cancer.
Methods: In this descriptive-analytical study, 111 women with breast cancer, who had undergone mastectomy surgery, were studied. Demographic and clinical characteristics of patients were extracted from their medical files and recorded in a questionnaire. Data were analyzed through SPSS 22 and by using descriptive statistics, ratios differences, mean differences and linear regression.
Results: Mean age of patients was 49.8± 10.9 years and mean BMI was 27.4 ± 5.4 Kg/m2. Mean number of removed lymph nodes was 7.8 ± 5.2 and in 50% of the patients, mean number of involved lymph nodes after the surgery was 4.2 ± 3.5. The disease was significantly more prevalent among those who were employed, married, had academic education, and aged over 45 years. According to Linear regression model, each 1.06 year age increase was significantly associated with one more removed lymph node and each gravidity increase was associated with one less removed lymph node and approximately two more involved lymph nodes after the surgery.
Conclusion: The results showed that age and gravidity are the most effective factors in the development of lymphadenopathy, especially in increasing the involved lymph nodes after the surgery. Therefore, enhancing the awareness of women about appropriate screening methods for early detection of breast cancer and regular check-ups after surgery is essential to reduce the probable problems.
 
Keywords
breast cancer; Surgery; Pregnancy; lymph node
References
  1. Sakorafas GH, Krespis E, Pavlakis G. Riskestimation for breast cancer development; aclinicalperspective. SurgOncol 2002; 10(4): 183-92.
  2. ChuKC, Tarone RE, KesslerLG,Ries LA, Hankey BF, Miller BA, Edwards BK. Recent trends in U.S. breast cancerincidence, survival, and mortality rates.JNatl Cancer Inst 1996: 88 (21): 1571-9.
  3. World Health Organization (W. H. O). Fact sheet N 297 February 2009; Available at: http://search.who.int/search?q=Fact+sheet+N+297+February+2009&ie=utf8&site=who&client=_en_r&proxystylesheet=_en_r&output=xml_no_dtd&oe=utf8&getfields=doctype
  4. Akbari A, RazzaghiZ, Homaee F, Khayamzadeh M, MovahediM, Akbari ME. Parity and breastfeeding are preventive measures against breast cancer in Iranian women.Breast Cancer 2011; 18(1):51-5.
  5. Mousavi SM, Montazeri A, MohagheghiMA, Jarrahi AM, Harirchi I, NajafiM, Ebrahimi M. Breast cancer in Iran: anepidemiological review. Breast J 2007; 13(4): 383-91.
  6. LamyianM, Heidarnia AR, Ahmadi F, FaghihzadehS, AguilarVafaie M. Women’s prospect of breast cancer early detection behavior: a qualitative research. J BirjandUniv Med Sci 2008; 15 (3):88-102.
  7. Khodaparast M. The effectiveness of cognitive-behavior interventions on depression and anxiety in cancer patients under chemotherapy [dissertation]. Tonekabon: Islamic Azad University 2011.
  8. Ghiasvand R, Bahmanyar S, ZendehdelK, Tahmasebi S, Talei A, Adami H-O, CnattingiusS.Postmenopausal breast cancer in Iran; risk factors and their populationattributable fractions. BMC Cancer 2012; 12(1):414.
  9. Brady-West DC, Graham SA. Prevalence of risk factors in breast cancer patients at the university hospital of the West Indies.West Indian Med J 2000; 49(2): 161-3.
  10. Hertz-Picciotto I, Tseng M, Newman B, Schroeder J, Vine M. Breast cancer and lactation history in Mexican women. Am J Epidemiol 1998; 147(8): 795-6.
  11. Boyd NF, Byng JW, Jong RA, FishellEK, Little LE, Miller AB, Lockwood GA, TritchlerDL, Yaffe MJ. Quantitativeclassification of mammographic densitiesand breast cancer risk: results from theCanadian National Breast ScreeningStudy.JNatl Cancer Inst 1995; 87(9):670-5.
  12. Romieu I, Hernández-Avila M, Lazcano E, Lopez L, Romero-Jaime R. Breast cancer and lactation history in Mexican women. Am J Epidemiol 1996; 143(6): 543-52.
  13. Lee HP, Gourley L, Duffy SW, Estève J, Lee J, Day NE. Risk factors for breast cancer by age and menopausal status: a case-control study in Singapore. Cancer causes control 1992; 3(4):313-22.
  14. American Cancer Society (ACS), cancer Facts & Figures, (2008), Atlanta: GA, American Cancer Society; 2008
  15. Fentiman IS. Fixed and modifiable riskfactors for breast cancer. Int J ClinPract2001: 55(8): 527-30.
  16. Herdy V. Education: a key factor in fighting breast cancer. New York: Inter press services; 1998
  17. Statistical Centreof Iran. National Population and Housing Census, 2011: Selected Findings. Tehran: Statistical Centre of Iran; 2012.
  18. Ziaeibigdeli M, Kalantari S, Alizadeaghdam M. The Relationship between Fertility Rate and Socio-Economic Development. Social Welfare Quarterly 2006: 5 (21) :123-40
  19. Baniasadi M, Aflatoonian MR, Rooholamini R, Aflatoonian B, Abbasi R. Effective Internal Factors in Improvement of Patients Undergoing Breast Cancer Surgery Using a Logistic Regression Model.Iranian Journal of Epidemiology 2014; 10(1): 9-14.
  20. Rajaeefard A, Mohammad-Beigi A, Mohammad-Salehi N. Estimation of natural age of menopause in Iranian women: A meta-analysis study. koomesh 2011; 13 (1) :1-7.
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