The relationship between pregnancy and frequency of lymph nodes removed and involved after surgery in women with breast cancer by linear regression model

Document Type: Original Article


1 Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran.

2 Cancer, Cancer Research Center Shahid Beheshti University of Medical Science Tehran Iran.


Background: Breast cancer is the most common cause of cancer death among women in the world and in Iran,which is increasing in Iranian women. The aim of this study was to determine the relationship between pregnancyratesand involved andremovedlymph nodes after mastectomy surgery in women with breast cancer.
Methods: In this descriptive-analytical study,111 women with breast cancer, who had undergone mastectomy surgery, were participated. Demographicand clinical characteristics of patients were extracted from their medical records, and recorded in the questionnaire. Datawere analyzed using descriptive statistics, ratios differences, mean differences, and linear regression by SPSS 22.
Results: The mean age of the patients was 49.8± 10.9 yearsand their BMI was 27.4 ± 5.4 Kg/m2. An average number of 7.8 ± 5.2 lymph nodes were removed thatin 50% of the patients, the average number of 4.24.2 ± 3.5 lymph nodeswere re-involved. The disease was significantly more prevalent among those who were occupied, married, had academic education, and aged over 45 years.Linear regression model showed that significantly by increasing every 1.06 years of aging,one more lymph node was removed, and every pregnancy leaded to one less lymph nodes removal, while nearly two more lymph nodes involved after the surgery.
Conclusion:The results showed that age and parity were the most effective factors in thedevelopment of lymphadenopathy, especially in increasing the involved lymph nodes after the surgery. Therefore, enhancing the awareness of women about appropriate screening methods for early detection of breast cancer and regular check-ups after surgery is essential to reducethe damage.


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