Dengue Fever Serology in Febrile Patients in Southeast Iran

Document Type: Short Communication


1 Professor, Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

2 Professor, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran

3 Resident of Bacteriology, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran

4 Associate Professor, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging infectious diseases, Pasteur Institute of Iran, Tehran, Iran

5 Researcher, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran


Background: Dengue is a mosquito-borne viral disease that has rapidly spread in all regions in recent years. There is little information on dengue fever epidemiology in Iran. High prevalence of dengue fever in Pakistan bordering southeast Iran emphasizes the need for paying more attention to monitoring of the disease in this region. The aim of this study was to study the dengue fever seropositivity among adult febrile patients in southeast Iran.
Methods:Dengue fever virus specific IgG antibodies were measured by a commercial enzyme-linked immunosorbent assay (ELISA) in sera of 184 patients.
Results: All examined sera were negative.
Conclusions:The existence of dengue fever in eastern borders of Iran and tracking the virus vectors in the southeast Iran can be a treat for the circulation of the virus in Iran; however, we did not find any track of the seropositivity in this study and despite the high prevalence of dengue fever in Pakistan bordering southeast Iran, no dengue positive cases were found in this study. This epidemiological research is significant for local health authorities.


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