Document Type : Original Article
Authors
- Maryam Dalili 1
- shahrzad Moeinaddini 2
- hosein Gozashti 3
- Mehdi Torabi 4
- Moghadameh Mirzaee 5
- Afsaneh Mahdizadeh 6
1 Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iranan University of Medical Sciences
2 Department of Obstetrics and Gynecology, School of Medicine, Endocrinology and Metabolism Research Center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran Department of Obstetrics and Gynecology, School of Medicine, Endocrinology and Metabolism Research Center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran
3 Department of Internal Medicine, School of Medicine, Endocrinology and Metabolism Research Center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iranan University of Medical Sciences
4 Department of Emergency Medicine, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran
5 Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
6 Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran
Abstract
Background
In order to detect the gestational diabetes mellitus (GDM) in pregnant women as soon as possible, the aim of this study was to investigate the role of ultrasound in predicting GDM at early pregnancy by measuring the thickness of abdominal subcutaneous adipose tissue.
Methods and Materials
This was a longitudinal study performed on pregnant women at the weeks of 11 to 14 of pregnancy. All the women referred during this time were screened for the thickness of abdominal subcutaneous adipose tissue, which was measured by trans-abdominal ultrasound. The patients were followed up by performing the oral glucose tolerance test (OGTT) between the weeks of 24-28. Finally, abdominal subcutaneous adipose tissue thickness and other variables were compared between women with and without GDM. Oral consent was obtained from patients.
Results
210 pregnant women were enrolled in the study. The mean of abdominal subcutaneous adipose tissue thickness was measured by ultrasound as 1.72 ± 0.33 mm. There was a statistically significant relationship between GDM and ultrasound-derived subcutaneous adipose tissue thickness (P <0.0001). At the cut-off point of 2.01, the sensitivity, specificity, and area under curve (AUC) values were 91%, 92%, and 0.96, respectively.
Conclusion
Measuring the thickness of the abdominal subcutaneous adipose tissue at early pregnancy may be useful in predicting GDM in the second trimester of pregnancy. Maternal higher age and weight gain, increased parity, and positive family histories of diabetes, preeclampsia, hypertension, and recurrent abortion may also increase the risk of GDM.
Highlights
Maryam Dalili(Google scholar)(Pubmed)
Shahrzad Moeinaddini(Google scholar)(Pubmed)
Mohammad Hossein Gozashti(Google scholar)(Pubmed)
Mehdi Torabi(Google scholar)(Pubmed)
Moghaddameh Mirzaee(Google scholar)(Pubmed)
Afsaneh Mahdizadeh(Google scholar)(Pubmed)
Keywords
Main Subjects
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