Document Type : Original Article
Authors
1 NEUROLOGY RESEARCH CENTER, KERMAN UNIVERSITY OF MEDICAL SCIENCES
2 Neurology Research Center, Kerman University of Medical Sciences
3 Kerman University of Medical Sciences
4 Ph.D of knowledge and information science. Department of Scientometrics at Kerman University of Medical Sciences, Kerman, Iran.
Abstract
BACKGROUND: Cerebral Venous Thrombosis (CVT) is a rare disorder with a prevalence of five per million people annually. This study aimed to evaluate CVT risk factors and its relationship with optic coherence tomography (OCT).
METHODS: This study conducted on 30 patients with CVT and 30 healthy individuals. The CVT diagnosis was confirmed by neuroimaging. After that, the patients underwent OCT. Also, healthy individuals who didn’t have any disease were randomly selected from the staff and were examined by an ophthalmologist. The eye examination was normal. They underwent OCT and macular thickness and RNFL were evaluated.
RESULTS: The most of patients were female (80%). The mean age of them was 34.98±3.78 years old. Headache was the most common symptom (66.7%). Pregnancy was observed in all patients in case group (zero in the control group) and was associated with CVT (P= 0.03). The thickness of the inferior temporal layer in case group was greater than control group (P= 0.04). The thickness of the superior temporal layer in patients with papilledema was larger than patients without papilledema (P=0.02). Women in the postpartum period increase the odds of developing CVT by 18.61 times (p= 0.03).
CONCLUSIONS: The results of this study suggest that macular thickness decreases in patients with CVT but the thickness of different RNFL layers increases in patients with CVT. The clinical value of these findings is unknown.
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