Comparisso of intralesionally injected Zink sulfate and pentavalent Antimony compound in treatment of acute cutaneous leishmaniasis
A.R
GHafarinejhad
Assistant professor
author
F
Iraji
Assistant professor
author
A
Vali
author
A
Asiliyan
professor
author
M.A
Shah-Talebi
Associate professor
author
text
article
2000
eng
acute cutaneous leishmaniasis(ACL) is an endemic disease in developing countries.the first line drug for treatment of ACL.according to WHO recommendation,is the pentavalent antimony compounds such as meglumine antimoniate(Glucantime{SB}).high cost ,side effects,multiple injections and incomplete efficacy are limitations of this therapy.we evaluated the efficacy of intralesional(IL) injection of zink sulfate 2% in treatment of ACL and compared that with efficacy of IL injection of glucantime(sb).this prospective double-blind case control clinical trial was performed on 104 patients with typical lesions of ACL and positive direct smear.these patients were treated by IL injection of contents of one of two similar vials A or B.the vials were coded by an independent physician.the pateints were seen in two weeks intervals and injection was repeated when reqiered.improvement was evaluated by clinical examination and direct smear.follow-up period was six weeks.66 patients were followed until 6 weeks(35 patients from A group and 31 from B group). after 6 weeks,the cure rates were 60% for A solution and 83.87 % for B solution.after 2,4 and 6 weeks of treatment ,the responses to therapy with A solution were respectively 3.5+_1.14,3.68+_1.11 and 3.8+_1.05 versus 3.84+_1.11,4.6+_1.25,3.85+_1.24 for B solution.after second and forth weeks,the efficacy of treatment with B solution was higher than A solution (p<0.01),but after six weeks no significant differences were observed between two groups (p>0.05).after only one injection of B solution,cure rate was 54.84% reinjection significantly increased efficacy of A,but not of the B solution,Asolution was Glucantime and B solution was zink sulfat 2%.on the basis of this trial,treatment of ACL by intralesional injection of zink sulfate 2% may be effective.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
161
166
https://jkmu.kmu.ac.ir/article_34230_6225fea7094960b613d72a8a733d44e6.pdf
Comparison of the effect of single and triple dose of antibiotic prophlaxis on post cesarean section intection
N
Eftekhari
Assistant professor
author
Z
Salari
author
text
article
2000
eng
following cesarean infection is one of the main complications,and antibiotic prophylaxy is an important protective factor in reduction of postoperational infection.the aim of this study is to compare the prophylactic effect of single dose ampicillin to triple dose ampicillin following the operation.this prospective randomized clinical trial a total of 242 women were prophylactically treated with ampicilin following the cesarean section.the subject were divided equally into three groups,group one received three doses and the second group received a single dose of the drug following clamping of the cord.the average age of the women,gestation age,and the duration of the surgery were the same.the most common reason fpr the c-section was the previous history of having a C-section,and the most common type of incision was fannensteil.no significant difference was observed in wound infection between the fiest and second group.(3.3% compared to 9.9%), although endometritis was higher in the group one (1.7%) than in the second group (0.8%).8.2% in the first group and 9.9% in the second group showed febrile reactions,however the difference was not significant different.the results indicates that there is no significant difference observed in infection rate and febrile reactions.therefore a single dose of ampicillin is recommended,for prophylactic pourpose following cesarean section.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
167
172
https://jkmu.kmu.ac.ir/article_34231_10d73fef435a9c68d6d4d3c7254c7c2b.pdf
A study on antimicrobial activity and chemical compositions of Essential oils from flowers of lavandula anguifolia and salvia officinalis
I
Rasooli
Assistant professor
author
M.B
Rezaei
Assistant professor
author
text
article
2000
eng
chemical compositions and antimicrobial effects on E.coli and S.aureus of essential oils from lavandula anguifolia and salvia officinalis were stuied.disk diffusion method was conducted to evaluate the zone of microbial growth inhibition at 1,1:.2,1:.8 and 1:16 dilutions of the essenial oils at four stages of zero(fresh oil).1,2 and 3 months post-exeaction.the antimicrobial effect was also studied against 10_7 ml.10_6 ml amd 10_5ml concentrations of microbial cells to find out minimal inhibitory concentration(MIC) and minimal Bactericidal concentration(mbc).the Essential oils were bactericidal against both the micro organisms.comparatively,Gram negative bacterium E.coli,was readily affected by the
Essential oil of lavandula anguifolia and S.aureus was redily affected by the Essential oil of salvia officinalis.chemical compositions of Essential oils were analyzed by Gas chromatography and Mass spectrometry(GC and GC/MS). twelve common chemical compounds of A-Humulene,a-pinene,B-pinene,a-thujene,1,8-camphor,Cis-B-ocimene,Linalool,P-Cymene and Terpinene-4-ol were found at various concentrations in both the oils,most of which were monoterpenes.Major components of Essential oil of salvia officinalis were B-pinene(16%),Berneol(9.4%),Glubulol(9.3%),a-humulene(8.4%),a-thujene(6.4%),a-pinene(5.5%),Camphene(5%), and those of lavandula anguifolia were linalol(36.9%),1,8-Cineole(16%),B-orneol(11.5%),canphor(4.2%) and terpinene-4-ol (4.19%) It seems that monoterpenes give antibacterial property to the essential oils.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
173
181
https://jkmu.kmu.ac.ir/article_34232_1241b5e84ff65e1fa66a4bff4a628a8f.pdf
Investigation of the prevalence of Torus Mandibularis and Torus palatinus in Attendants of rafsanjan Dental school
M.N
Khaki
Assistant professor
author
text
article
2000
eng
the prevalence of Torus palatinus and Torus Mandibularis is widely different in various populations and races.this descriptive study was performed in 1999,to investigate the the prevalence of Torus Mandibularis and Torus palatinus in patients referring to Rafsanjan dental school.584 patients(268 men and 316 women) which were over 18 years old were examined.the information recorded in the questionaires were analized by EP16 software resulting 14.2% for torus palatinus (10.4% in men and 17.4% in women). and 4.6% for tours mandibularis (6.7% in men and 2.8% in women).
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
182
187
https://jkmu.kmu.ac.ir/article_34233_60abe1c07eba06602dfa423047f41a56.pdf
Asurvey on the incidence of chronic suppurative otitis media(C.S.O.M) in Kermanian school children aged 12 to 15 years
K
Mozafari-nia
Assistanr professor
author
M
Hakakzadeh
author
text
article
2000
eng
chronic suppurative otitis media(C.S.O.M) in a chronic infective and chronic inflammatory process of middle ear and mastoid that may be with or without cholesteatoma.Due to its significant problems and complications such as hearing loss,labyrinthitis,facial nerve paralysis,meningitis,brain abscess,extra and subdural BSCESS AND LATERAL SINUS THROMBOSIS IS A FATAL AND IMPORTANT DISEASE.IN THIS STUDY 177-78(98-99) 3137 Kermanian school children aged 12 to 15 years from 174 schools were andomly checked for C.S.O.M Overage incidence rates of C.S.O.M was 5.7 per thousand,(female 0.5% and male 0.7%).Average of hearing loss was 25 db.there was no significant correlation between the incidence of C.S.O.M and underlying disease or factors such as sex,parental education and smoking(p>0.05)
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
188
193
https://jkmu.kmu.ac.ir/article_34234_970060b0baa414ba67a77c4447206170.pdf
Prevalence of foreward head posture and its relationship with different variables in the Shiraz high school students in 1999
F
Moslemi-Haghighi
Instructor
author
M.R
Fotoh-abadi
Instructor
author
A
GHanbari
Instructor
author
text
article
2000
eng
Since posture is of great importance in pernosal health & social life,so evaluation of prevalence of
foreward head posture in school children of adolesent age seems necessary for proper prevention planning and treatment.the present study is an analytic-descriptive on 480 students(240 girls and 240 boys) from Shiraz high school in 1999.the subjects were selected according to clusture random sampling.the relationship between foreward head posture with some variables such as sex,position of studying,visual disorder and physical activity was investingated.the questionnaire was filled for each subject,then posture of foreward head was measured by plumbline.the results indicated that the incidence of fpreward head posture from right and left was 76.1% and 74.6 % respectively and there was a significant difference between foreward head with sex,position of studying and doing excercise(p<0.05),but is not with the visual dsorder.the results of this study indicate a relatively high incidence of foreward head posture in study population.to prevent occurence and aggrevation of this untoward situation,a wide spread planning for teaching of general population,parents and public health teachers as well as sports teachers seems necessary.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
194
199
https://jkmu.kmu.ac.ir/article_34235_0d0259e0eb0405e9d5ca6c6c9e4e4f82.pdf
L(+) lactic acid production and separation from dairy wastes(whey):in situe separation of lactic acid using lon-exchange resins in automatic control of PH.
S.A
Ataei
Instrutor
author
text
article
2000
eng
Whey with a large amount of BOD(50000 PPM) is a dangerous environmental pollutant.this important source of lavtose(4-5%) is A USEFULL SUBSTRATE FOR A RANGE of fermentation processes.lacitic acid with swvwral applications in industries is one of these products.Specially L(+) isomer of this acid worthing 10 times as much as the mixture of L&D,is used in medical purposes such as absorbable surgical filaments and controlled release drugs.several strains of lactobacillus produce a mixture of L&D isomers but the strain employed in this research(lactobacillus casei)produces only L(+) form.the prodices lactic acid prevents acid production in fermentation,so that almost half of lactose (about 22 g/l lactic acid) is converted to lactic acid.therefore in order to increase the output the produced acid should be separated.in this research lactobacillus casei was used to produce L(+) lactic acid and due to strile conditions requirement in situe separation of acid using Ion-exchange resins at control automatic of Ph were employed.at the end,lactic acid yield in non extractive fermentation compared with extractive process showed an increase from 22g/l to 43.7g/l.the polarimetric analysis showed pure L(+) product.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
200
205
https://jkmu.kmu.ac.ir/article_34236_8e83dfb2ad76327ca13469cbfa75e44b.pdf
Therapeutic effect of dapson in six cases of Granuloma Annulare
S
Zandi
Assistant professor
author
I
Esfandyarpour
Assistant professor
author
text
article
2000
eng
Granuloma Annulare is an flammatory bening skin disease that may manifest different clinical features.the most common presentation or classic form of the disease is fleshcolor,annulare,grouped papules,disseminated forms are rare and responses to treatments are vnot satisfactory.various treatment modalities have been used for this disorder and different responses to treatments have been reported.in a few studies the satiafactory therapeutic effects of dapsone in granulomma annulare have been reported.dapsons has been used in the treatment of many dermatosis such as pemphigoid,herpetiform dermatitis,bullons lesions of systemic lupus erythematosus,pyoderma gangrenosum.recurrent polychndritis,acne conglobata,etc.dapsone has been introduced as an effective systemic drug with low side effects in the treatment of granuloma annulare,including disseminated and subcutaneous forms-in this study six patients with skin biopsy were examined patholosicalls and diagnised as having granulomma annulare were treated with dapsone for a period of two months.in four cases the skin lesions were completely disappeared,but in two cases the therapeutic effects were 50% and 20%.these two patients showed recurrence of thier lesions after discontinuation of dapsone therapy.
Journal of Kerman University of Medical Sciences
Kerman University of Medical Sciences
1023-9510
7
v.
2
no.
2000
206
211
https://jkmu.kmu.ac.ir/article_34237_e6489740ee512fed663102722568249b.pdf