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37 weeks and cervical dilatation of 3-4 cm, referring to labor room of Zeinabieh and Hafez hospitals in Shiraz were devided into case group (N=63) and control group (N=58). The case group smelled lavender essential oil for 1 hour. In both groups anxiety changes were determined before and after aromatherapy by Spielberger questionnaire, and at the same times pulse rate, blood pressure and plasma cortisol, serotonin, and 5-HIAA concentrations were determined by ELISA. Results: Anxiety status and hormone levels were the same in both groups at the beginning of the experiment. Lavender decreased significantly anxiety and cortisol concentration while increased plasma serotonin and 5-HIAA concentrations. The difference between cortisol concentration before and after the aromatherapy in the test group was significantly lower than that of the control group. Lavender scent did not affect blood pressure and pulse. Conclusion: Aromatherapy with lavender improves anxiety status during labor in nulliparous women and decreases cortisol secretion from adrenal gland and increases serotonin secretion from GI tract.]]>
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