@article { author = {Atapour, N and Niyazi, M}, title = {ffects of morphine_ dependence on the induction and modulation of epileptic seizures in rats}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {153-158}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {Kindling is a very suitable animal model for studying basis mechanisms of epilepsy. In this model , repeated exposure to weak electrical or chemical increases neuronal excitability and there fore decreases the threshold for induction of epileptic seizures. According to abundant distribution of opioid peptides and their receptors in different brain structures and also the role of these receptors on the excitability of neurons,we studies the effects of repeated morphine administration on the induction and modulation of epileptic seizures. Male rats were made dependent by gradual increase in concentration s of morphine sulphate in drinking water. Then, pentylenetetrazole ( PTZ,30 mg\ kg) was injected intraperitoneally at 48 hours interval and epileptic seizures of control and dependent rats were compared in 22 serial injection s. In another series of experiment, morphine _ dependence was induced after kindling and 20 days later, seizures response s to a single subtreshold dose of PTZ were compared. The results showed that morphine dependence, facilitate s the induction of chemical kindling, but when kindling is induced , morphine _ dependence has no effect on it. It seems  that morphine _ dependence has important effects on the neuronal excitability that is presented as facilities of kindling induction in this study.}, keywords = {Epilepsy,kindling,Morphine,Pentylenetetrazole}, url = {https://jkmu.kmu.ac.ir/article_34295.html}, eprint = {https://jkmu.kmu.ac.ir/article_34295_de074a5ae7c5c901f879d227ef05b4ad.pdf} } @article { author = {Fati, A.M and Baradaran, H and Dadvar, P}, title = {Blood serum level of immunoglobulins in patients with Hymenolepis Nana infection}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {159-164}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Hymenolepiosis is a common intestinal tapeworm infection among children. To Investigate the relation of the level of blood serum immunoglobulins, with hymenolepiosis a study was undertaken at Mean Reza hospital, Mashhad. The blood specimens of  100 patients infected with Hymenolepis Nana who had no other intestinal parasitic infection and were clinically health as cases and 50 healthy person s whoes stool exams were negative for three times as controls were collected. Immunoglobulins of all cases and control s were measured by SRID and ELISA methods and compared by t- test . The results showed that the level of IgH and IgG of cases were significantly higher than the control group ( p<0.05) but there was no significant difference in IgA and IgM levels. It is concluded that immunological change especially stimulation of humoral immunity may result in partial or complete protection against further infections.}, keywords = {Hymenolepis Nane,Immunity,immunoglobulins,immunodianosis}, url = {https://jkmu.kmu.ac.ir/article_34297.html}, eprint = {https://jkmu.kmu.ac.ir/article_34297_fbe578682be3f7f7d3e3b8ab2af54d3d.pdf} } @article { author = {Vojdani, M.H and Nahaei, M.R and Jorabchi, H and Razavi-Motlagh, S.M}, title = {Study of Asymptomatic bacteriuria in pregnant women and antibiotic _ sensitivity of isolated bacteria in Tabriz 1996}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {165-170}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {Urinary tract infection ( UTI) is a common disease , which may occur as Asymptomatic in both sexes at any age. Asymptomatic bacteriuria in pregnant women can particularly cause problems for both mother and her fetus. Therefore in this study 950 pregnant women who have been referred to Tabriz university and private, gynaecology clinics for routine pregnancy cares, and had no sign s of UTI were selected according to simple random sampling method. Their clean catch midstream urine were tested for 10 CFU/ ml). E. Coli proved to be the most prevalent organism (85℅) causing Asymptomatic bacteriuria in our patients. Other bacteria isolated were as follows: staphylococcus saprophyticus (5℅), Proteus mirabilia (4℅), streptococcus app.(2℅), klebsiella spp (2℅) , staphylococcus aureus(1℅) and enterobacter aerogenes(1℅). When antibiotic sensitivity patterns were performed according to Kirby_ Bauer method on our E. Coli strains the following sensitivity patterns were observed: amikacin(100℅), nalidixic acid(94.6℅), nitrofurantoin(90℅). Sensitivity of other isolated organisms are also discussed in detail. Results of our study indicate the presence of Asymptomatic UTI (10.5℅) in the pregnant women studies in Tabriz and underlined the need for recognition and treatment of them to prevent further problems in both pregnant women and their fetus.}, keywords = {Pregnant,urinary tract infection( UTI),bacteriuria,Asymptomatic bacteriuria,antibiotics sensitivity}, url = {https://jkmu.kmu.ac.ir/article_34298.html}, eprint = {https://jkmu.kmu.ac.ir/article_34298_6a735de19e7d3ec58e835d4aa5039080.pdf} } @article { author = {Karamifar, H and Mehranband, SH}, title = {Prevalence of stress Hyperglycemia among patients attending to the neonatal and pediatric Emergency wards of Shiraz university of medical sciences}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {171-177}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  The aim of this study was to determine the prevalence and clinical characteristics associated with stress Hyperglycemia among patients attending to the neonatal and pediatric Emergency wards. Patients who require d blood sampling for evaluated of an acute illness from August 1995 to July 1996 to the Namazi hospital of Shiraz medical university were enrolled prospectively for Hyperglycemia ( plasma glucose>150 mg/ DL). A total of 1620 patients ranging from 3 days to 16 years were enrolled. Plasma glucose values ranged from 29 mg/ DL to 593 mg/ DL. 206 patients (12.7℅) had Hyperglycemia. The prevalence of stress Hyperglycemia was significantly higher among patients if they: 1. Were neonates and infants <2 year (20.22℅) versus older children 2_6 year ,(9.8℅), 6_12 year (3.25℅) and adolescents 12_16 year (5.1℅) ( p<0.001). 2. Had acut illnesses (27.2℅) versus more chronic disease (6.8℅) ( p<0.001). 3. Several dehydrated (75.9℅) versus not several dehydrated (10.4℅) ( p<0.001).4. had convulsions in their  recent illness (29.7℅) versus not having convulsions (8.5℅) ( p<0.001). 5. Had vomiting and diarrhea in recent illness (40.3℅) versus not having vomiting and diarrhea (9.1℅) ( p<0.001). 6. Had unstable vital signs (44.3℅) versus stable vital signs (7.5℅) ( p<0.001).7. had been admitted to an intensive care unit, neonatal ICU (80℅), pediatric ICU (62.5℅) and neonatal Emergency room (21.8℅) ( p<0.02). It is concluded that stress Hyperglycemia is a frequent clinical occurrence in a pediatric emergency departments, and it does not appear to be specifically associated with any particular disease but is significantly related to  the severity , acuity of the illness and state of hydration of the patient.  }, keywords = {Hyperglycemia,Stress,neonates,Pediatrics}, url = {https://jkmu.kmu.ac.ir/article_34299.html}, eprint = {https://jkmu.kmu.ac.ir/article_34299_d319fff7f4ac195b0e9c02a52b7c3068.pdf} } @article { author = {Kamyabi, Z and Aflatonian, M.R and Bahrampour, A}, title = {Determination of the mean age of menopause and it's distribution terms of known variables in Kerman}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {178-185}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  This research is a cross _ sectional and descriptive study for determining of the mean age of menopause and related factors in Kerman province. The sample included 2000 of Kerman families which chosen by clustering method, and the women of 40_60 years were studied. The women who had not become menopause physiologically were omitted. So the sample size decreased to 224(102 urban, 122 rural). The data collected by questionnaire. The mean age of menopause for the whole population was 48 and this characteristics for the physiological menopause was 48.4. the results showed that the being urban and rural, occupation, education, husband's occupation, gravids, parities, abortions and children make no significancy on mean age of menopause. Also it showed that there was no significancy between age of first gravida  and age of menopause, but if the last gravida was after 45 it could delaying the menopause significantly( p<0.01). Besides long term oral contraceptives can affected on delaying of menopause ( p<0.01). There was no significancy between smoking and menopause age.  The mean age of those women who had gynecological operation was less than the other s. Finally it's concluded that the mean age of menopause in this region is less than the international reports.}, keywords = {menopause,mean age,Effective Factors,contraceptives pill,cigarett}, url = {https://jkmu.kmu.ac.ir/article_34300.html}, eprint = {https://jkmu.kmu.ac.ir/article_34300_95003d5afb4edf49866981047dd7b08d.pdf} } @article { author = {Shamsi-Memandi, S and Hagh dost, A.A and Nakhaei zadeh, R}, title = {Prevalence of skin disorders in athletes of 10 sport activities}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {186-192}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Participation in sport activities has become increasingly popular, as a result, more patients are referred 10 dermatologists for disorders caused by sport activities. During most forms of exercise, the skin and it's appendages are under constant assault by traumatic and other environmental factors that can cause injury. Physical activity also predispose s the skin to infection and can exacerbate a preexisting dermatosis. This is a cross _ sectional descriptive study of sport dermatologic disorders among athletes from Kerman who were members of sport _ clubs. 201 athletes in 10 fields of sport were selected by clustering. Control group were  Kerman medical student s who were selected randomly, they exercise not too often , and they were not members of sports clubs. Dermatologic exam was done on both groups.Average age of involved athletes were 21.1 years old. Involved were 19 and control group were 21.2 years old. The prevalence of skin disease were more in athletes 38℅ than control group 11℅ ( p<0.01). Seven types of skin disorders were seen in athletes in frequency : 1_ callus, -2 Acne mechanics,.3- corn,4- Tinea versicolor,5- athlete,s nodules, 6- Tina pedis, 7- urticaria. Three types of skin lesions were observed in control group in order of frequency; 1- Corn, 2- Acne mechanics,3- Tinea versicolor. The average sport time was 4.9 years in unaffected cases and was 6.3 years in affected ones. Our results suggest higher prevalence of skin lesions in athletes. The prevalence of skin lesions increased with increasing in age and sport time. On the other hand, the prevalence of skin disorders in athletes using sport instrument s were 3.3 times more than one s who didn't use any sport instrument. It is needed to be concerned about dermatologic problems in athletes.}, keywords = {sport,dermatologic disorders}, url = {https://jkmu.kmu.ac.ir/article_34301.html}, eprint = {https://jkmu.kmu.ac.ir/article_34301_1332af31e41f82dfd8181ddd0c436a37.pdf} } @article { author = {Rostamipour-dolatabadi, A and Heidarnia, A.R and Mohammadalizadeh, S and Faghihzadeh, S}, title = {A survey on knowledge,attitude and health behavior of kahnujian rural women concerning malaria in 1997}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {193-200}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Currently the control policy of malaria is based on the patient,s treatment,killing of the larvae and application of insecticides, whereas the important factors such as knowledge , attitude and health behaviour have been mostly ignored. This study was carried out to determine. Knowledge, attitude and health behaviour of 517 women in rural areas of Kahnujian city. The subjects were selected by multi-stage random sampling and data from them were collected  by filling in questionnaire during face to face inter view. The results showed that the women,s scores on knowledge and attitude were 38.1℅ (X=15.2, SD=2.1) and about 83℅ (X=62.2, SD=6.3) respectively. The mean score for knowledge was significantly higher in women with more education (p<0.003). Concerning the health behaviour, the result indicated that 30℅ of the responders used bednet and only 3℅ of them covered their windows with small size wire grids. However , the other common methods for protection and prevention were rarely used by the subjects. Our results suggest that in order to prevent and control malaria the common measure ( including the treatment of the patients and application of insecticides, etc.) Should not only be applied but also methods such as improving the health behaviour, knowledge, attitude and contribution of people should  be considered.}, keywords = {Malaria,health behaviours,knowledge,Attitude}, url = {https://jkmu.kmu.ac.ir/article_34302.html}, eprint = {https://jkmu.kmu.ac.ir/article_34302_87f148b50c6d0f7b39a823145ab94fe4.pdf} } @article { author = {Rajabi, J and Arkani, E and Abdolahian, E}, title = {The effects of high-dose propranolol in psychiatric patients: a report of 4 cases}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {2}, pages = {201-206}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Since the first report in 1977, many studies have been carried out to determine the efficacy of beta- blockers such as propranolol for the treatment of violent  and aggressive behaviour. Propranolol has also  been used in the treatment of dementia, attending- deficit disorder, schizophrenia, personality disorders, Korsakoff,s psychosis, posttraumatic stress disorder, profound mental retardation, autism and brain injury. Doses of prescribed propranol have been varied from 60 to 1440 mgs per day. Though the mea range 260 to 400 mg per day is more common . In the present study, 4 patients diagnosed as paranoid schizophrenia, bipolar mood disorder, mental retardation, and disorganized schizophrenia who did not respond to the conversational drug treatment were chosen. Propranolol with doses higher than 250 mg/ day was administered. The main symptoms and signs targeted for the treatment were; severe aggression, impulsive homicidal outburst, grossly impaired functioning . Propranolol was administered in doses of 250_440 mg/ day ( high doses) and higher doses were not required. According to the clinical psychiatrist and the reports from the nursing staff and patients relatives, the efficacy of propranolol in high doses was satisfactory. This study suggests that further similar controlled investigations are needed to be carried out in different areas.}, keywords = {Propranolol,Violence,high doses}, url = {https://jkmu.kmu.ac.ir/article_34303.html}, eprint = {https://jkmu.kmu.ac.ir/article_34303_d3532a23b59790dd59f80b416429239b.pdf} }