@article { author = {Najafipour, H}, title = {Investigation of sympathetic mechanism of inverse relationship between scalp and leg blood flow with increasing intracranial pressure in the rabbit}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {53-59}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {Intracranial pressure (ICP) is one of most important factors in determining health and function of cerebroscular system. However the methods of measuring ICP are usually invasive . In an attempt to find a noninvasive method to assess ICP, in previous study web found a reverse relationships between changes in ICP and blood flow in scalp (SBF) and leg skin (LSBF) . In this study the role of sympathetic nervous system in mediating this relationship was Investigated. Ten NZW rabbits were anaesthetized and their femoral artery and vein cannulated to record blood pressure, and inject the drugs. Another cannula was inserted into the subdural space following the skin incision and craniotomy in parietal region. Scalp and leg skin areas were shaved and the laser Doppler flowmeter probes were placed over them to record the flow, on two channels of recorder . Arterial pressure and ICP were recorded on the other two recorder channels through blood pressure transducers connected to related cannulae. After recording base line values, phentolamine ( a- blocker) was injected through venous  (1.2 mg/ kg); and 45 min later, ICP was increased in 9 steps from 1.2 +_ 0.2 mmHg to 20+_0.2 mmHg. (2 mmHg each step, 3 min apart) by augmentation of a saline reservoir connected to ICP cannula. Blood pressure (BP) . SBF and LSBF were recorded simultaneously.BP was reduced from 91.5+_3.7 to 72.5+_2.2 mmHg, SBF from 157+_28  to 37+_40 and LSBF from 169+_26 to 114+_20 arbitrary units by phentolamine. ICP increment had no effect on  SBF, but increased the LSBF to normal level ( 173+_43 arbitrary units), and increased BP to 100.6+_6.7 mmHg . The correlation coefficient between changes in ICP and SBF was zero ( compared to -0.84 in normal animals in previous study) and between ICP and LSBF was +0.19 ( compared to -0.39 in normal animals) . Overall the results showed that, sympathetic nervous system  is the mediator of changes in SBF and LSBF due to changes in ICP as reverse relationships between ICP and SBF and LSBF in normal animal was blocked and changed to direct relationship respectively in phentolamine treated animal. }, keywords = {Alteration of intracranial pressure,skin blood flow,sympathetic nervous system}, url = {https://jkmu.kmu.ac.ir/article_34312.html}, eprint = {https://jkmu.kmu.ac.ir/article_34312_5d444668caf37520dfd896dc720c62a9.pdf} } @article { author = {Haghighi, A and Rezaian, M}, title = {The cultivation of entamoeba histolytica in HSr+ s medium}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {60-64}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  In 1926 for the first time Dobell and laid low synthesized and used Hsre+ s ( horse serum, ringer, egg+ starch rice) as a culture medium for growth of E.histolytica. since then this medium along with tens of other media have been used for growth of E.histolytica and other intestinal microorganisms. This medium has been used worldwide in many diagnostic and research laboratories. In Iran, in the past two decades they have used this medium in the school of public health and Institute of public health research. Rezaeian and (1989) simplified the original formula by not using the albumin of the egg and they found the same efficiency for the cultivation of Amoeba in HSr+ s medium. Since Oct.1996 , we have used HSr+ s medium for cultivation and diagnosis of Entamoeba histolytica. Eighty five percent of stool culture with Entamoeba ( cyst or trophozoite) have been positive, furthermore E. histolytica were cultured in the medium, with the average growth rate of 100000/ ml which indicates an efficient growth rate.}, keywords = {Entamoeba histolytica,HSr+ s medium,scenic cultivation}, url = {https://jkmu.kmu.ac.ir/article_34313.html}, eprint = {https://jkmu.kmu.ac.ir/article_34313_83ebf94506d4e9a271eb32dffd057f82.pdf} } @article { author = {Soleimani, F and Moshtaghi, GH.R}, title = {Erythrocyte fragility in hyperthyroid patients}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {65-71}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Mild anaemia among patients with hyperthyroidism, reduction in intracranial zinc content of erythrocytes and anti- haemolysis of whole blood of patients with Graves, disease under laboratory Condition are the facts which indicate that although erythrocytes are devoid of receptors for thyroid hormones, they are affected by the excess of these hormones. In order to find out the reasons for such changes, osmotic fragility of the erythrocytes were investigated in peripheral blood of hyperthyroid patients ( n=40) using phosphate buffers ( pH=7.38) that contained different concentration s of sodium chloride. These patients had the clinical symptoms for at least two weeks. The results obtained in this study showed that the erythrocytes of these patients at concentration of 72 mmol/L of sodium chloride were 21.67℅ more fragile compared to that of healthy control group ( p<0.001) (n=20). The erythrocytes lysis could be due to reduction of plasma total lipids or excessive work load of these cells during thyrotoxicosis. Another possibility could be the impairment of intracellular electrolytes and other elements which are essential for the proper functioning of these cells. Finally, it may be concluded that the erythrocytes of hyperthyroid patients in this study were more fragile than that healthy controls.}, keywords = {Osmotic fragility,hyperthyroidism}, url = {https://jkmu.kmu.ac.ir/article_34314.html}, eprint = {https://jkmu.kmu.ac.ir/article_34314_eedb022af1981e5c7f7a81725ab659ef.pdf} } @article { author = {Ketabchi, A.A}, title = {Urogenital and fertility complications in victims of chemical war residing in Kerman province}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {72-77}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {In this research urogenital complications of 300 veterans with the average age of 32.7+_6.5 years were studied for two years( 1995-1996) . They were selected randomly in Kerman province based  on having at least one exposure to chemical warfare, six to ten years before the study. The control group was selected among the troops whom were not exposed to chemical warfare and had an average age of 31.8+_6.2 years. The study was performed bases on a physical examination, sperm count, and hormonal tested. In the test group,infertility was 23.3℅ spouse- miscarriage 13.6℅ spermogram abnormality 38.7℅ , decrease in libido 30℅ , sexul importancy 9℅ , and finally premature ejaculation 23.6℅ . In the control group the results were, 1.6℅ ,2.6℅ ,8.3℅ ,6℅ ,0.3℅ and 4.3℅ respectively. All of this data showed a significant difference between the troops whom were exposed to chemical warfare and those whom were not. Newborn abnormalities among chemically exposed troops were 9℅ , while in the control groups was 1℅. Hormonal investigation in the test group showed an increase of FSH in 57.6℅ of cases and LH in 66.3℅ if cases. In 26.6℅ of cases, the spouses of chemically affected troops were suspected to have symptoms their skin, eyes and lungs similar to that of their husbands. The result of this study showed that chemical warfare mainly affects the reproductive and neuroendocrine systems, and gave the highest effect on the testes ( Gonads), and therefore causing abnormalities in spermatogenesis , sexual activity, and probably resulting in mutations in fetus and newborn.}, keywords = {Mustard sulfor,Infertility,impotency,spermatogenesis,chemical warfare}, url = {https://jkmu.kmu.ac.ir/article_34315.html}, eprint = {https://jkmu.kmu.ac.ir/article_34315_b05f160528372cf440c375e2cccbdbc4.pdf} } @article { author = {Ali, B.SH and Kariminik, A and Bahrampour, A and Sodir, N.D}, title = {Comparision of the effect of myrtus communis extract and clotrimazole on candida albicans isolated from patients with candida vaginitis}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {78-83}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {There are many reports about antifungal and antimicrobial effects of Myrtle extract. In respect to resistance of fungal strains to current antifungal drugs such as imidazole derivatives, a comparative study was carried out to Investigate the antifungal effect of Myrtle extract versus clotrimazole on candida albicans, the most common cause of vaginal candidiasis . The vaginal discharge of 500 patients complaining of vaginitis symptoms attending the women's clinic of Bahonar hospital were cultured in specific and selective medium ( Nikerson medium) for isolation of candida species. Based on macroscopic appearance of the colonies and germ tube test, 80 positive cultures of candida albicans were isolated. Metabolic extract of Myrtle leaves was prepared by maceration method and filter paper disks containing 20 mg of either the extract or clotrimazole was provided. The positive samples were tested by disc diffusion method. Results showed that the antifungal effect of methanolic extract was greater than that of clotrimazole ( p<0.001) . There was a positive correlation between inhibition zone diameter of clotrimazole and Myrtle extract ( r= 0.86) . The mean inhibition zone surface of Myrtle  extract was 1.28 times of clotrimazole.}, keywords = {Clotrimazole,Myrtle communis extract,candida albicans}, url = {https://jkmu.kmu.ac.ir/article_34316.html}, eprint = {https://jkmu.kmu.ac.ir/article_34316_69e30e3bcf8f958407d168bdcd3f237f.pdf} } @article { author = {Hamzehi-Moghadam, A and Bahrampour, A and Mobasher, M}, title = {The evaluation of migraine prevalence and associated demographic factors among government employees of Kerman city}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {84-91}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {  Migraine is one of the most common chronic neurologic disorders that is prevalence among the people of working age, and causes episodic incapacity for work in some sufferers. Migraine imposes an enormous health burden and great expenses on sufferers and society. To evaluate the frequency of migraine and it's relation to some demographic factors on a sample of government employees in Kerman city. A study was conducted among 1029 employees of 20 government offices in Kerman that were selected through cluster random sampling method. From 1029 subjects under the survey ,473 (46℅) of the individuals were women and 556 (54℅) were men of which 659 (64℅) suffered from headache. According to HIS diagnostic criteria 107 of the subjects suffered from migraine headache. Among this group 67 (62.6℅) of the subjects were women and 40 (37.4℅) were men. The prevalence rate of migraine in our study was 10.4℅ . Range of the population was 26-45 years old and average age of this group was 36.1 years old. This average age was higher than of the nonmigraine employees in our study. Most of migrainous employees had an employees, background of 10-14 years  and mean of employees, background in males was higher. Based on the result of this study a significant correlation ( p<0.05) was found between migrain and , age sex, and years of the employment. The prevalence of migrain was highest among the age group of 36-45 years (14.7℅) also highest among females and employees with the longest employment. The highest disease occurrence has been found among employees with 10-14 years of experience ( p<0.05) and a significant correlation was found between employment years and the prevalence of migraine ( p<0.05)}, keywords = {migraine,Prevalence,Employees,Epidemiology}, url = {https://jkmu.kmu.ac.ir/article_34317.html}, eprint = {https://jkmu.kmu.ac.ir/article_34317_e99b4a3f993db386855a330f1efef3fe.pdf} } @article { author = {Farajzadeh shikh, A and Hemati, Y}, title = {Study of the prevalence of Gardnerella vaginalis isolated from vaginal discharges of patients referred to outpatient clinic of Taleghani hospital in Tehran}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {92-98}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {In this study in order to determine prevalence of Gardnerella vaginalis and sensitivity of the organism to antimicrobial agents specimens were treated in  the outpatient clinic of Taleghani hospital in Tehran. Specimens were considered positive for bacterial vaginosis (BV) which were positive three times out of four. The tests include; finding clue cell, amine  test, homogenesity of this discharges, and PH. To isolate the bacteria, discharges were cultured on human blood bilayer twin 80 ( HBT), the isolated strains were tested for antibiotic sensitivity. The results indicated that 67.5℅ of the patients had bacterial vaginosis. Based on the results of culturing the isolated colonies, and the results of the biochemical conformational tests, 23.8℅ of the patients were infected with Gardnerella vaginalis, out of these 82℅ were in people who had bacterial vaginosis. No significant correlation was found between the presence of Gardnerella vaginalis and number  labour's and abortions, however there was a significant correlation with the application of IUD among the subjects. Study of the stained smears made from the discharges, indicated that there was a significant correlation between reduction of lactobacilli population, elevation in the number of gram variable bacteria, and the presence of Gardnerella  vaginalis ( p<0.05). The results obtained from antibiotic  sensitivity tests indicated that the isolated strains of Gardnerella vaginalis was sensitive to ampicillin (10 mg), sulfomethoxazol + trimethoprim (25 mg) , nitrofurantoin (300 mg) , metronidazole (50 mg), nitrofurantoin 300 mg, chloramphenicol (30 mg) , tetracycline (30 mg), and resistant to metronidazole (10 mg).}, keywords = {Bacterial vaginosis,Gardnerella vaginalis,vaginal discharge,Metronidazole,sensitivity patterns}, url = {https://jkmu.kmu.ac.ir/article_34318.html}, eprint = {https://jkmu.kmu.ac.ir/article_34318_602eb03cbeaf71256bedd9729bcc051a.pdf} } @article { author = {Mozafari nia, K}, title = {Elongated styloid process ( eagle,s syndrome): A case report}, journal = {Journal of Kerman University of Medical Sciences}, volume = {5}, number = {4}, pages = {99-102}, year = {1997}, publisher = {Kerman University of Medical Sciences}, issn = {1023-9510}, eissn = {2008-2843}, doi = {}, abstract = {The patient is a 19 year old man from Kerman. His chief complain is dysphagia and a stabbing unilateral sore throat for the past two years. His other symptoms  are painful sensation in the right tonsilar fossa, painful deglutioon and sensation of pain which increases and radiates during speaking, physical excretion and deep breathing . Patient admitted that he has had several periods of hospitalization , and a tonsillectomy operation. Physical examination of ENT reveals no pathological findings, however in lateral radiography of the neck, an elongated styloid process was observed. Therefore the patient underwent resection surgery ( trans- tonsillar- fossa approach) with the diagnosis of elongated styloid process. A week later all of the symptoms were resolved and the patient was released from the hospital.}, keywords = {Elongated styloid process,Eagles syndrome,Stylagia}, url = {https://jkmu.kmu.ac.ir/article_34319.html}, eprint = {https://jkmu.kmu.ac.ir/article_34319_4f6ee947185b74e89235a16f5808e495.pdf} }