Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Determination of the sensitivity and secificity of hypertrophy of hyponychium as a new diagnodtic sing in down syndrome
1
6
EN
M.H
Daei-Parizi
professor
M.T
Yasemi
A.A
Vahidi
Assistant professor
down syndrome is the most common known chromosomal disorder in man.this syndrome has many sings and symptoms which are variable in frequency.taking all the signs and symproms in to consideration,diagnosis of down syndrome is not a difficult task-however in the past it was difficult to diagnose this syndrome based on a single clinical sign,until hypertrophy of hyponichium was first introduced by daie(1988) as a new sign,that is seen in all of down syndrome patients.to determine precisely the sensitivity and specificity of this sign and its frequenxy in different fingers and toes,this research was conducted on 67 infants and children with down syndrome and 82 normal controls.
sensitivity of hypertrophy of hyponychium in diagnose of down syndrome was found to be 100% with the confidence interval of 95%(93.24-100) and the secificity of 98.78%(92.45-99.94) the frequency of this clinical sign was highest in the hands particularly the third and fourth fingers.thus,it is now possible to clinically ndiagnose this syndrome with high level of confidence following careful examination of fingers in newborns.
Sensitivity,secificity,hypertrophy of hyponychium,down syndrome,21-trisomy
https://jkmu.kmu.ac.ir/article_34320.html
https://jkmu.kmu.ac.ir/article_34320_86bd55c419166b696e45b5d0e1bb4f92.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Cytogenetic analysis of 1284 cases of Down syndrome
7
16
EN
M.H
Kariminejhad
professor
R
Kariminejhad
F
Azimi
N
Nabavi nia
K
Alavi
M.T
Takyar
Y
Shafeghati
Assistant professor
Among 17786 karyotyres performed in our center,during 18 years (1357-1375),1300(7.3%) cases of chromosome 21 aberration,including 1284(98.77%) of Down syndrome have been detected.1191 of cases (92.76%) born free trisomy 21:61 cases (4.75%) revealed translocation and 32 cases (2.4%) showed mosaic pattern.among the pateints,59 had robertsonian translocation,2 had translocation between chromosome 21 and a non acrocentric chromosome designated as chromosomes 7 and 8.among the 1284 patients with chromosome 21 aberration,735 were male and 549 female with a Mto F ratio of 1.34:1-cytogenetic study of 18 parents of DS children with robertsonian translocation revealed that 4 cases(22.22%) were inherited from the carrier mothers.there were also 4 translocation in non G chromosomes,which were inherited from either parent.in general 8 of the 23 parents(34.78%) including 6 mothers and 2 fathers transmitted the involved chromosome to their children in the other 15 cases primary translocation occured.two of the DS were also associated with klinfelter syndrome (48,XXY+21) and one male child born 47,XY+21, 5p+Cri du chat).our findings are almost similar to the large group studies of other investigators.
trisomy of 21,down syndrome,cytogenetic,chromosomal translocation,mosaicism
https://jkmu.kmu.ac.ir/article_34321.html
https://jkmu.kmu.ac.ir/article_34321_62bd0242be9d6b37434d5c0158f24162.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Preparation and evaluation of latex agglutination technique for diagnosis and seroepidemiological studies of visceral leishmaniasis
17
23
EN
M
Moheb-Ali
Associate professor
M
Mohammadi
in this study which has been carried out from 1996 until 1997 soluble latex agglutination antigen was prepared from L, donovani,sudan(s-1) by culturing in special media,harvesting,and later solubilizing by freezing and thawing.the antigen were futher prepared by high speed centrifugation.after measurement of the protein (lowry method) concentration of the antigen was set at 2.2 mg/ml,the antigen was coated in 2 to 1 ratio with latex beads (0.8 mm) and futher diluted 1:100.following preparation of latex agglutination antigen,210 human plasma samples and 57 dog plasma samples from Meshkin-Shahr district were tested by latex agglutination test(LAT),direct agglutination test (DAT) and indirect flourescence antibody test (IFAT).also 924 plasma samples from children >9 years old and 15 dog plasma samples from Kordan village,savegbolagh district,licated in Karaj in west of Tehran were tested by LAT,DAT and Enzyme linked immunosorbent assay(ELISA).the results show that the sensitivity of the LAT in human samples was 98% and in dog samples 96%.concordance between LAT and DAT in human samples is 80% and in dog samples is 89.4%.
latex agglutination,visceral leishmaniasis,Diagnosis,Seroepidemiology
https://jkmu.kmu.ac.ir/article_34322.html
https://jkmu.kmu.ac.ir/article_34322_240ec7692ffee8e9369ef41872d71cd9.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Comparison between rectal administration of diazepam in solution and intravenous administration for management of convulsive disorders in infants and children
24
30
EN
P
Niknafs
professor
A
Ahmadi
Associate professor
JH
Saraf zadeh
In order to compare rectal and intravenous(IV) administration of diazepam for management of convulsions,a prospective cross-sectional case-control study was conducted on 94 convulsive infants and children referring to the Emergency department of the university hospital No.1 in Kerman.all children were randomly divided into two groups.the patients were matched with regard to the cause,type,duration of the seizure and age.in group receiving rectal administration 46 patients received 0.5 mg/kg diazepam in solution using a lubricated insulin syring without the needle and in IV administration group,48 patients received diazepam at the dose of 0.2-0.3mg/kg through the peripheral veins,in group receiving rectal administration a single dose of diszepam solution was effective in stopping seizure in 37 patients(80.4%).in IV administration group,although IV access failed in 11 cases(23%) 33 out of 37 patients (98%) responded to a single dose of IV diazepam.the difference between IV and rectal administration of diazepam in control of seizure was statistically significant(p=0.04)more than half of the patients who were resistant to the rectal route did not respond to IV route either.the response latency for rectal administration was 3.3+_1 minutes and for IV administration was 2.78+_0.93(p=0.03).it is concluded that,although IV administration of diazepam is the method of choice for acute management of convulsive disorders,when IV access is impossible the best alternative is rectal administration of diazepam in solution.
convulsion,rectal diazepam,intravenous diazepam
https://jkmu.kmu.ac.ir/article_34323.html
https://jkmu.kmu.ac.ir/article_34323_efc255a670dcd1f5be5597f30e587839.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Determination of the prevalence of mental illnesses in 2 rural areas of Kerman
31
36
EN
S.H
MOtamedi
M.T
Yasemi
H
Karbasi
GH
Bani vaheb
Based on the WHO reports,1% of world population suffer from a sever psychological disorders,and 5-15% suffer from a mild disorder.based on the present informations in Iran,1-6 percent of the people above 15 years of age suffer from a severe psychological disorder and 15.2% suffer from the mild form of the disease.to investigate the epidemiology of mental illnesses in two rural areas of Baft,(Gugher and khabre) and denerate baseline data for future comparisons (after integration of mental health into primary health care),SCL -90-R questionaire was filled for 1086 inhabitants.all the permanent inhabitants (excluding nomads)over 15 years of age were given symptoms checklist 90 revised (SCL-90-R) which has been standardized for Iranian population.Drop-out nrate was not significant(2 men and 3 women).the point prevalence of mental disorders was 41.1%.the prevalence of mild,moderate,and severe disorders were 31.3% ,8% and 0.3% respectively.somatic problems were the most prevalent(54.3%) and phobia the least(18.5%).all the scales were higher in women than in men,and similar studies in Iran.however,some studies using other questionaires other than SCL-90R have reported similar results.based on the findings of this study itis recommended to provide mental health services for rural population especially high risk groups such as women.
Prevalence,mental illnesses
https://jkmu.kmu.ac.ir/article_34324.html
https://jkmu.kmu.ac.ir/article_34324_99aec0dabe03390f94fce9e6275b0f9e.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Evaluation of the nutritinal status of the primary-school childern based on weight and hight in Kerman,Iran
37
43
EN
A.A
Vahidi
Assistant professor
A
Ahmadi
Associate professor
M
Salehi
Instructor
M
Fasihi
the aim of this study was to find out the nutritional status of primary-school childern.for this purpose the weight and height of 599 boys and 750 girls in age group of 6-11 year olds were measured.their nutritional status were evaiuated according to the weight-for-age(Gomez),weight-for-hight(Waterlow) and weight/height-for age(McLaren-Read) methods.the Gomez method showed that 59.4% of the boys and 60.3% of the girls are undernourished.According to the waterlow method 35% of the boys and 28.8% of the girls are malnurished and the McLaren-Read method showed that 40.7% of the boys and 52.9% of the girls are suffering from various degrees of malnutrition.there was no significant difference between acute malunutrition(weight for age) and present malunutrition (weight for height) in the boys and the dirls,but chronic malunutrition (height for age) had a significant difference in the two genders.this study showed that the present and past nutritional status of more than half of the children is not desirable and about one third of them are suffering from chronic malunutrition.therefore,in order to decrease the rate of undernutrition,which may have unfavorable effects on mental and physical statue of children,beside improvement of economic conditions of the families the ministry of health,treatment and medical education should also take specific measures.
Nutritional Status,acute malnutrition,chronic malunutrition,Height,Weight,Gomez,waterlow,mclaren-read
https://jkmu.kmu.ac.ir/article_34325.html
https://jkmu.kmu.ac.ir/article_34325_77f05ec0ef13f30f1c4898dc04658e99.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
Incidence of fat embolism syndrome in patients with long bone and/or pelvic fracture admitted to Shahid Bahonar hospital in Kerman
44
48
EN
H
Khatibi
Assistant professor
N
Matlabizadeh
this study was carried out from October 1993 through November 1995(26 months).during this period 3472 patients(2743 male and 729 female) with long bone and/or pelvic fracture were admitted in different wards of Shahid Bahonar hospital of Kerman.based on the Gurd criteria,25 of these patients (24 male,1 female) were suffering from fat embolism sundrome(FES).incidence of FES in this study was 7.1 per thousand patients(male 8.7 and female 1.4 per thousand).Frequencies of fractures with FES were as follow:female 16,,tibia 11, pelvis 2,foream 2, and humerus 1.positive clinical and laboratory findings were:24 cases of respiratory symotoms,20 cases of conjunctival and axillary petechia.19 cases of central nervous alteration,17 cases of cardiovascukar abnormalities,16 cases of fever, and 3 cases of hemoptysis.case fatality rate in this study was 4 % (1 case with undisplaced tibial and pelvis fracture).according to our findings,probability of FES accurrence after a single fracture for each bone was:pelvis and femur 2% and 0.24% tibia.18 cases (76%) of FES occurs within first 48 hours and 22 (88%) cases within 72 hours post injury.incidence of FES was more than six times in males compared to females.
Incidence,fat embolism,bone fracture
https://jkmu.kmu.ac.ir/article_34326.html
https://jkmu.kmu.ac.ir/article_34326_e70df8336f75083a0e8a13e980060592.pdf
Kerman University of Medical Sciences
Journal of Kerman University of Medical Sciences
1023-9510
2008-2843
4
1
1997
12
01
A case report of Uterine-ovarian pregnancy after 13 years
49
52
EN
T
Naderi
Assistant professor
H
Zeinali
Assistant professor
Naturaly blastocyte implants in the uterine cavity.implantation of blastocyst in anyplace other than the endometrial lining of the uterine cavity is considered an ectopic pregnancy.more than 95% of ectopic pregnancies are tubal pregnancies.ovarian ectopic pregnancy is a rare case with an estimated incidence ranging from % 0.05-1 of the extra uterine pregnancies.if one blastocytes implant simultaneously in the uterine cavity and the other anywhere else other than uterine cavity it is referred to as heterotype pregnancy.this is a rare type of pregnancy and depends on implantion place of the second blastocyte and is named uterine-ovarian,tubal-uterine or...... pregnancy.this is a case report of uterine-ovarian pregnancy in which a live child was born about 13 years ago however a calcified and a term twin fetus remaining in the ovary was taken out with laparotomy.
Pregnancy,Ectopic pregnancy,ovarian-uterine pregnancy
https://jkmu.kmu.ac.ir/article_34327.html
https://jkmu.kmu.ac.ir/article_34327_d8d7c85cc81c3db4315b6f464935ac3b.pdf