Journal of Kerman University of Medical Sciences

Frequency of Seropositivity for anti-Coxiella Burnetii (Phase II) among Veterinary Staff in Southern Khorasan, Iran, in 2014

Authors

Mohammad Khalili 1
Mohammad Reza Aflatoonian 2
Mohammad Rahanjam 3
Mehdi Golchin 4
Hamid Sharifi 5
Behnaz Aflatoonian 6

1 Associate Professor, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman AND Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

2 Instructor, Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

3 Master of Bacteriology, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

4 Associate Professor, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

5 Assistant Professor of Epidemiology, Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

6 Researcher, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran

Abstract
Background and Aims: Q fever is a public health concern in many countries especially in recent years. There are a few studies in Iran. This study aimed to determine the seropositivity for Q fever among veterinary staff in southern Khorasan, Iran. Methods: 92 serum samples were obtained from all veterinary employees and tested using an indirect enzyme-linked immunosorbent assay (ELISA). The data including age, sex, education, having contact with the secretion of cattle abortion, and keeping animal in house were analyzed using descriptive statistics and confidence interval of 95%, and chi-square and logistic regression tests. Results: Totally, 54.3% of serum samples were positive (57.1% in men and 40.0% in women). The results of logistic regression showed that in people who had contact with the secretions of cattle abortion the odds ratio was 2.3 times more than those who had not contact with livestock abortion. Other factors did not show any significant relationship. Conclusion: These data indicate high seropositivity in veterinary staff of southern Khorasan. Thus, training this high-risk group of people looks to be necessary to prevent the disease. In addition, complementary studies in other parts of Iran are suggested to clarify the epidemiological aspects of Q fever in this group.

Keywords

Seropositivity
Q fever
Veterinary staff
Iran
  1. Lang GH. Coxiellosis (Q fever) in animals. In: Marrie TJ, Editor. Q fever: the disease, Volume 1. Boca Raton, Florida: CRC Press; 1990. p. 23-48.
  2. Maurin M, Raoult D. Q fever. Clin Microbiol Rev 1999; 12(4): 518-53.
  3. Guatteo R, Seegers H, Taurel AF, Joly A, Beaudeau F. Prevalence of Coxiella burnetii infection in domestic ruminants: a critical review. Vet Microbiol 2011; 149(1-2): 1-16.
  4. Angelakis E, Raoult D. Q fever. Vet Microbiol 2010; 140(3-4): 297-309.
  5. Waag DM. Coxiella burnetii: host and bacterial responses to infection. Vaccine 2007; 25(42): 7288-95.
  6. Carrico R. APIC text of infection control and epidemiology. 3rd ed. Anchorage, AK: Alaska Process Industry Careers Consortium; 2009.
  7. Berri M, Rousset E, Champion JL, Russo P, Rodolakis A. Goats may experience reproductive failures and shed Coxiella burnetii at two successive parturitions after a Q fever infection. Res Vet Sci 2007; 83(1): 47-52.
  8. Khalili M, Mosavi M, Diali HG, Mirza HN. Serologic survey for Coxiella burnetii phase II antibodies among slaughterhouse workers in Kerman, southeast of Iran. Asian Pac J Trop Biomed 2014; 4(Suppl 1): S209-S212.
  9. Khalili M, Sakhaee E. An update on a serologic survey of Q fever in domestic animals in Iran. Am J Trop Med Hyg 2009; 80(6): 1031-2.
  10. Aflatoonian MR, Khalili M, Sami M, Abiri Z. Frequency anti-coxiella burneti Ig M in Kerman Slaughterhouse Personals. J Kerman Univ Med Sci 2014; 21(5): 368-75. [In Persian].
  11. Khalili M, Shahabi-Nejad N, Golchin M. Q fever serology in febrile patients in southeast Iran. Trans R Soc Trop Med Hyg 2010; 104(9): 623-4.
  12. Esmaeili S, Pourhossein B, Gouya MM, Amiri FB, Mostafavi E. Seroepidemiological survey of Q fever and brucellosis in Kurdistan Province, western Iran. Vector Borne Zoonotic Dis 2014; 14(1): 41-5.
  13. de Rooij MMT, Schimmer B, Versteeg B, Schneeberger P, Berends B, Heederik D, et al. Risk factors of coxiella burnetii (Q Fever) seropositivity in veterinary medicine students. PLoS One 2012; 7(2): e32108.
  14. Naderipour Z, Golchin M, Khalili M. Design of an ELISA kit for detection human acute Q fever. Iran J Med Microbiol 2014; 8(2): 28-34. [In Persian].
  15. Azizzadeh M, Mohammadi GR, Haghparast AR, Heidarpour M. Seroepidemiology of coxiella burnetii in commercial dairy herds in northeast of Iran. Iranian Journal of Veterinary Science and Technology 2011; 3(2): 33-40. [In Persian].
  16. Asadi J, Khalili M, Kafi M, Ansari-Lari M, Hosseini SM. Risk factors of Q fever in sheep and goat flocks with history of abortion. Comparative Clinical Pathology 2014; 23(3): 625-30.
  17. Metanat M, Sepehri RN, Alavi-Naini R, Shahreki S, Sharifi-Mood B, Akhavan A, et al. Acute Q fever among febrile patients in Zahedan, southeastern Iran. Turk J Med Sci 2014; 44(1): 99-103.
  18. Gunal O, Barut S, Ayan M, Kilic S, Duygu F. [Investigation of Coxiella burnetii and Brucella seropositivities in patients presenting with acute fever]. Mikrobiyol Bul 2013; 47(2): 265-72.
  19. Norlander L. Q fever, epidemiology and pathogenesis. Microbes and Infection 2000; 2: 417-24.


Journal of Kerman University of Medical Sciences
Volume 23, Issue 2
2016
Pages 164-173

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