Document Type : Short Communication

Authors

1 Professor, Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran

2 Professor, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran

3 Resident of Bacteriology, Department of Pathobiology, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran

4 Associate Professor, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging infectious diseases, Pasteur Institute of Iran, Tehran, Iran

5 Researcher, Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran

Abstract

Background: Dengue is a mosquito-borne viral disease that has rapidly spread in all regions in recent years. There is little information on dengue fever epidemiology in Iran. High prevalence of dengue fever in Pakistan bordering southeast Iran emphasizes the need for paying more attention to monitoring of the disease in this region. The aim of this study was to study the dengue fever seropositivity among adult febrile patients in southeast Iran.
Methods:Dengue fever virus specific IgG antibodies were measured by a commercial enzyme-linked immunosorbent assay (ELISA) in sera of 184 patients.
Results: All examined sera were negative.
Conclusions:The existence of dengue fever in eastern borders of Iran and tracking the virus vectors in the southeast Iran can be a treat for the circulation of the virus in Iran; however, we did not find any track of the seropositivity in this study and despite the high prevalence of dengue fever in Pakistan bordering southeast Iran, no dengue positive cases were found in this study. This epidemiological research is significant for local health authorities.

Keywords

  1. Morin CW, Comrie AC, Ernst K. Climate and dengue transmission: evidence and implications. Environ Health Perspect 2013; 121(11-12):1264-72.
  2. Chan M, Johansson MA. The incubation periods of dengue viruses. PLoS One 2012; 7(11):e50972.
  3. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature 2013; 496(7446):504-7.
  4. World Health Organization (WHO). Global strategy for dengue prevention and control 2012–2020 [cited 2019 February 3]. Available from: https://www.who.int/denguecontrol/9789241504034/en/
  5. Rico-Hesse R. Dengue virus markers of virulence and pathogenicity. Future Virol 2009; 4(6):581-9.
  6. Humphrey JM, Cleton NB, Reusken CB, Glesby MJ, Koopmans MP, Abu-Raddad LJ. Dengue in the Middle East and North Africa: a systematic review. PLoS Negl Trop Dis 2016; 10(12):e0005194.
  7. Kar M, Singla M, Chandele A, Kabra SK, Lodha R, Medigeshi GR. Dengue virus entry and replication does not lead to productive infection in platelets. Open Forum Infect Dis 2017; 4(2):ofx051.
  8. Doosti S, Yaghoobi-Ershadi MR, Schaffner F, Moosa-Kazemi SH, Akbarzadeh K, Gooya MM, et al. Mosquito surveillance and the first record of the invasive mosquito species aedes (stegomyia) albopictus (skuse) (diptera: culicidae) in Southern Iran. Iran J Public Health 2016; 45(8):1064-73.
  9. Arslan A, Rathor HR, Mukhtar MU, Mushtaq S, Bhatti A, Asif M, et al. Spatial distribution and insecticide susceptibility status of aedes aegypti and aedes albopictus in dengue affected urban areas of Rawalpindi, Pakistan. J Vector Borne Dis 2016; 53(2):136-43.
  10. Vorndam V, Kuno G. Laboratory diagnosis of dengue virus infections. In: Gubler D J, Kuno G, editors. Dengue and dengue hemorrhagic fever-1997. London, United Kingdom: CAB International; 1997. pp. 313–334. p. 313–333.
  11. Chinikar S, Ghiasi SM, Moradi A, Madihi SR. Laboratory detection facility of dengue fever (DF) in Iran: the first imported case. J Infect Dis 2009; 8(1):1-3.
  12. Aghaie A, Aaskov J, Chinikar S, Niedrig M, Banazadeh S, Mohammadpour HK. Frequency of dengue virus infection in blood donors in Sistan and Baluchestan province in Iran. Transfus Apher Sci 2014; 50:59-62.
  13. Siddiqui FJ, Haider SR, Bhutta ZA. Endemic dengue fever: a seldom recognized hazard for Pakistani children. J Infect Dev Ctries 2009; 3(4):306-12.
  14. Chinikar S, Ghiasi SM, Shah-Hosseini N, Mostafavi E, Moradi M, Khakifirouz S, et al. Preliminary study of dengue virus infection in Iran. Travel Med Infect Dis 2013; 11(3):166-9.
  15. Fatima Z, Idrees M, Bajwa MA, Tahir Z, Ullah O, Zia MQ, et al. Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks -2007-2009 in Pakistan. BMC Microbiol. 2011; 11:200.
  16. Jahan F. Dengue Fever (DF) in Pakistan. Asia Pac Fam Med 2011; 10:1-10.
  17. Jamil B, Hasan R, Zafar A, Bewley K, Chamberlain J, Mioulet V, et al. Dengue virus serotype 3, Karachi, Pakistan. Emerg Infect Dis 2007; 13(1):182-3.
  18. Yaghoobi Ershadi MR, Doosti S, Schaffner F, Moosa Kazemi SH, Akbarzadeh K, Yaghoobi Ershadi N. Morphological studies on adult mosquitoes (Diptera: Culicidae) and first report of the potential zika virus vector aedes (stegomyia) unilineatus (theobald, 1906) in Iran. Bull Soc Pathol Exot 2017; 110(2):116-21.