Document Type : Short Communication
Authors
1 Associate Professor, Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, and Department of Microbiology and Virology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
2 Associate Professor, Zoonosis Research Center, Tehran University of Medical Sciences, and Department of Medical Laboratory Sciences, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Background: Staphylococcus hominis has been recently emerged as an opportunistic hospital-associated pathogen. The aim of this study was to characterize the antimicrobial susceptibility pattern, biofilm formation, and staphylococcal cassette chromosome mec (SCCmec) types among clinical isolates of S. hominis obtained from pediatric infections. Methods: Totally, twenty- two clinically significant S. hominis isolates, mostly from blood samples, were examined for antibiotic resistance, SCCmec typing, and biofilm formation. Results: Multiresistance was observed in 86 % of isolates. Among mecA positive isolates (77%), SCCmec type I (28%), III (22%), IV (22%), and non-typeable ones (28%) were detected. More than half of the isolates (54.5%) did not produce biofilm. No significant association was found between biofilm formation and the presence of ica operon. Conclusion: As S. hominis isolates were not strong biofilm producers, biofilm formation cannot be considered as much as important multidrug resistance.in the pathogenesis of isolates.
Keywords
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