Document Type : Original Article
Authors
- Maryam Aliramezani 1
- Amin Mahdavi 1
- Mahshid Ghanbarnejad 1
- Mohammadjavad Zarrabi 1
- Sarehossadat Ebrahimi 2
- Maedeh Jafari 2
1 Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
2 Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Abstract
Background: Coronaviruses are a huge family of viruses that lead to various diseases from a common cold to more unadorned illnesses for example SARS-CoV and MERS-CoV. Common symptoms of this infection include respiratory symptoms. In addition, this disease can also manifest with an acute cardiovascular (CV) syndrome. The aim of this study was to determine the frequency of CV involvement in patients with COVID-19 disease admitted to Afzalipour Hospital in Kerman.
Methods: In this study, all patients who were diagnosed with COVID-19 disease and were hospitalized and monitored due to disease conditions were eligible to enter the study. At the beginning of the patient’s hospitalization, the patients’ vital signs were recorded and the first 12-lead electrocardiography was taken. Then, patients underwent cardiac monitoring and echocardiography at the beginning of hospitalization and afterwards during the course of disease. Preliminary tests including biochemistry, blood cell count, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) and troponin were also performed for patients.
Results: The mean age of patients with COVID-19 was 55.63 years and 20.2% of them had a history of heart disease. More than half of these patients were men. Ejection fraction was normal in 87.8% of patients. There was a significant relationship between diastolic dysfunction grade and the history of heart disease (P = 0.02).
Conclusion: Since the incidence of underlying diseases such as diabetes, hypertension and cardiac disorders can raise the risk of corona viruses’ disease and also increase the mortality rate of this disease in these people, it is suggested that more attention be paid to the observance of health protocols for people with underlying diseases, and that people with underlying diseases be given priority in vaccinating against this disease.
Highlights
maryam maryam aliramezani(google scholar)(pubmed)
Amin Mahdavi(google scholar)(pubmed)
mahshid ghanbarnejad(google scholar)(pubmed)
mohammadjavad zarrabi(google scholar)(pubmed)
Sarehossadat Ebrahim(google scholar)(pubmed)
Maedeh Jafari(google scholar)(pubmed)
Keywords
Main Subjects
- Moazenzadeh M, Jafari F, Farrokhnia M, Aliramezany M. First reported case of unrepaired tetralogy of Fallot complicated with coronavirus disease-19 (COVID-19). Cardiol Young. 2020;30(9):1339-42. doi: 1017/s1047951120001821.
- Silverio A, Di Maio M, Ciccarelli M, Carrizzo A, Vecchione C, Galasso G. Timing of national lockdown and mortality in COVID-19: the Italian experience. Int J Infect Dis. 2020;100:193-5. doi: 1016/j.ijid.2020.09.006.
- Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475-81. doi: 1016/s2213-2600(20)30079-5.
- Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62. doi: 1016/s0140- 6736(20)30566-3.
- Silverio A, Di Maio M, Citro R, Esposito L, Iuliano G, Bellino M, et al. Cardiovascular risk factors and mortality in hospitalized patients with COVID-19: systematic review and meta-analysis of 45 studies and 18,300 patients. BMC Cardiovasc Disord. 2021;21(1):23. doi: 1186/s12872- 020-01816-3.
- Russo V, Silverio A, Scudiero F, Micco PD, Maio MD. Pre-admission atrial fibrillation in COVID-19 patients: prevalence and clinical impact. Eur J Intern Med. 2021;88:133-5. doi: 1016/j.ejim.2021.03.017.
- National Institute for Health and Care Excellence: Clinical Guidelines. COVID-19 Rapid Guideline: Managing the Long- Term Effects of COVID-19. London: National Institute for Health and Care Excellence (NICE); 2020.
- Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27(4):601-15. doi: 1038/s41591-021-01283-z.
- Carfì A, Bernabei R, Landi F. Persistent Symptoms in Patients After Acute COVID-19. JAMA. 2020;324(6):603-5. doi: 1001/jama.2020.12603.
- Corrales-Medina VF, Alvarez KN, Weissfeld LA, Angus DC, Chirinos JA, Chang CC, et al. Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease. JAMA. 2015;313(3):264-74. doi: 1001/jama.2014.18229.
- Corrales-Medina VF, Musher DM, Shachkina S, Chirinos JA. Acute pneumonia and the cardiovascular system. Lancet. 2013;381(9865):496-505. doi: 1016/s0140- 6736(12)61266-5.
- Inciardi RM, Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D, et al. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):819-24. doi: 1001/jamacardio.2020.1096.
- Li FK, An DW, Guo QH, Zhang YQ, Qian JY, Hu WG, et al. Day-by-day blood pressure variability in hospitalized patients with COVID-19. J Clin Hypertens (Greenwich). 2021;23(9):1675-80. doi: 1111/jch.14338.
- Mahmoud-Elsayed HM, Moody WE, Bradlow WM, Khan- Kheil AM, Senior J, Hudsmith LE, et al. Echocardiographic findings in patients with COVID-19 pneumonia. Can J Cardiol. 2020;36(8):1203-7. doi: 1016/j.cjca.2020.05.030.
- Szekely Y, Lichter Y, Taieb P, Banai A, Hochstadt A, Merdler I, et al. Spectrum of cardiac manifestations in COVID-19: a systematic echocardiographic study. Circulation. 2020;142(4):342-53. doi: 1161/ circulationaha.120.047971.
- Abi Nassif T, Fakhri G, Younis NK, Zareef R, Al Amin F, Bitar F, et al. Cardiac manifestations in COVID-19 patients: a focus on the pediatric population. Can J Infect Dis Med Microbiol. 2021;2021:5518979. doi: 1155/2021/5518979.