Journal of Kerman University of Medical Sciences

Prevalence of Listeria monocytogenes Infection in Iranian Pregnant Women with and without a History of Abortion: A Systematic Review and Meta-analysis

Document Type : Review Article

Authors

Siavash Hamzeh Pour 1, 2
Reyhane Sefidkar 3
Ioannis Savvaidis 4
Elham Khalili Sadrabad 1, 5
Mehdi Fatahi-Bafghi 6
Fateme Akrami-Mohajeri 1, 5

1 Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

3 Center for Healthcare Data Modeling, Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

4 Department of Environmental Health Sciences, College of Health Science, University of Sharjah, Sharjah, United Arab Emirates

5 Department of Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

6 Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

https://doi.org/10.34172/jkmu.4112
Abstract
Background: Listeria monocytogenes (LM) is an important foodborne pathogen that can cause miscarriage, stillbirth, or premature birth of the fetus in pregnant women. This study aimed to investigate the prevalence of LM infection in Iranian pregnant women with and without a history of abortion.
Methods: A systematic search was performed in national (Iranian Scientific Information Database [SID], Magiran, IranMedex) and international (PubMed, Scopus, Web of Science) electronic databases for literature published between January 1, 1999, to the end of January 2022. Data analysis was done using R Studio software version 1.4.1717.
Results: In total, 17 studies, including 2553 women with a history of abortion and 1065 women without a history of abortion (3168 Iranian pregnant women), were included for the final analysis. The prevalence of LM infection in Iranian pregnant women with and without a history of abortion was estimated at 14% (95% CI: 13%–16%) and 5% (95% CI: 4%–7%), respectively. In addition, the incidence of the hlyA gene in Iranian pregnant women with and without a history of abortion was 11% (95% CI; 5%–22%).
Conclusion: The results of this study show that the prevalence of LM was higher in women who had a history of abortion compared to women without a history of abortion. Therefore, it seems that one of the possible etiological factors of abortion among Iranian pregnant women is the high prevalence of infection with LM.

Highlights

Siavash Hamzeh Pour (Google Scholar) (PubMed)

Keywords

Iranian woman
Listeriosis
Listeria monocytogenes
Pregnant woman
Prevalence
Subjects

  1.  

    1. Ranjbar R, Halaji M. Epidemiology of Listeria monocytogenes prevalence in foods, animals and human origin from Iran: a systematic review and meta-analysis. BMC Public Health. 2018;18(1):1057. doi: 10.1186/s12889-018-5966-8.
    2. Hamidiyan N, Salehi-Abargouei A, Rezaei Z, Dehghani- Tafti R, Akrami-Mohajeri F. The prevalence of Listeria food contamination in Iran: a systematic review and meta-analysis. Food Res Int. 2018;107:437-50. doi: 10.1016/j. foodres.2018.02.038.
    3. Zahedi Bialvaei A, Sheikhalizadeh V, Mojtahedi A, Irajian G. Epidemiological burden of Listeria monocytogenes in Iran. Iran J Basic Med Sci. 2018;21(8):770-80. doi: 10.22038/ ijbms.2018.28823.6969.
    4. Mook P, Grant KA, Little CL, Kafatos G, Gillespie IA. Emergence of pregnancy-related listeriosis amongst ethnic minorities in England and Wales. Euro Surveill. 2010;15(27):17-23. doi: 10.2807/ese.15.27.19610-en.
    5. Scharff RL. Economic burden from health losses due to foodborne illness in the United States. J Food Prot. 2012;75(1):123-31. doi: 10.4315/0362-028x.Jfp-11-058.
    6. Desai AN, Anyoha A, Madoff LC, Lassmann B. Changing epidemiology of Listeria monocytogenes outbreaks, sporadic cases, and recalls globally: a review of ProMED reports from 1996 to 2018. Int J Infect Dis. 2019;84:48-53. doi: 10.1016/j. ijid.2019.04.021.
    7. Li W, Bai L, Fu P, Han H, Liu J, Guo Y. The epidemiology of Listeria monocytogenes in China. Foodborne Pathog Dis. 2018;15(8):459-66. doi: 10.1089/fpd.2017.2409.
    8. Wadhwa Desai R, Smith MA. Pregnancy-related listeriosis. Birth Defects Res. 2017;109(5):324-35. doi: 10.1002/ bdr2.1012.
    9. Soni DK, Singh DV, Dubey SK. Pregnancy - associated human listeriosis: virulence and genotypic analysis of Listeria monocytogenes from clinical samples. J Microbiol. 2015;53(9):653-60. doi: 10.1007/s12275-015-5243-9.
    10. Kumar A, Grover S, Batish VK. Exploring specific primers targeted against different genes for a multiplex PCR for detection of Listeria monocytogenes. 3 Biotech. 2015;5(3):261- 9. doi: 10.1007/s13205-014-0225-x.
    11. Lotfollahi L, Nowrouzi J, Irajian G, Masjedian F, Kazemi B, Eslamian L, et al. Prevalence and antimicrobial resistance profiles of Listeria monocytogenes in spontaneous abortions in humans. Afr J Microbiol Res. 2011;5(14):1990-3. doi: 10.5897/ajmr11.498.
    12. Wang Z, Tao X, Liu S, Zhao Y, Yang X. An update review on Listeria infection in pregnancy. Infect Drug Resist. 2021;14:1967-78. doi: 10.2147/idr.S313675.
    13. Clauss HE, Lorber B. Central nervous system infection with Listeria monocytogenes. Curr Infect Dis Rep. 2008;10(4):300- 6. doi: 10.1007/s11908-008-0049-0.
    14. Charlier C, Perrodeau É, Leclercq A, Cazenave B, Pilmis B, Henry B, et al. Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study. Lancet Infect Dis. 2017;17(5):510-9. doi: 10.1016/s1473- 3099(16)30521-7.
    15. Wei P, Bao R, Fan Y. Brainstem encephalitis caused by Listeria monocytogenes. Pathogens. 2020;9(9):715. doi: 10.3390/ pathogens9090715.
    16. Flores-Perez RO, Villarreal-Villarreal CD, Cardenas-de La Garza JA, Galarza-Delgado DA. Supratentorial Listeria monocytogenes brain abscess in a patient with liver cirrhosis. Ann Indian Acad Neurol. 2020;23(1):107-9. doi: 10.4103/ aian.AIAN_233_18.
    17. Goulet V, Hedberg C, Le Monnier A, de Valk H. Increasing incidence of listeriosis in France and other European countries. Emerg Infect Dis. 2008;14(5):734-40. doi: 10.3201/ eid1405.071395.
    18. Allam M, Tau N, Smouse SL, Mtshali PS, Mnyameni F, Khumalo ZT, et al. Whole-genome sequences of Listeria monocytogenes sequence type 6 isolates associated with a large foodborne outbreak in South Africa, 2017 to 2018. Genome Announc. 2018;6(25):e00538-18. doi: 10.1128/genomeA.00538-18.
    19. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. doi: 10.1136/bmj.n71.
    20. von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies. Int J Surg. 2014;12(12):1495-9. doi: 10.1016/j.ijsu.2014.07.013.
    21. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557- 60. doi: 10.1136/bmj.327.7414.557.
    22. Kontopantelis E, Reeves D. Performance of statistical methods for meta-analysis when true study effects are non-normally distributed: a simulation study. Stat Methods Med Res. 2012;21(4):409-26. doi: 10.1177/0962280210392008.
    23. Brockwell SE, Gordon IR. A comparison of statistical methods for meta-analysis. Stat Med. 2001;20(6):825-40. doi: 10.1002/ sim.650.
    24. Farajzadeh Sheikh A, Haghroosta A, Vandyusefi J, Akhavizadegan M, Moradi Bidhendi S. Isolation of Listeria monocytogenes and determination of its antibody titers in women suffering from abortion. J Inflamm Dis. 2004;8(2):8- 13.
    25. Jamshidi M, Sotoodeh Jahromi A, Davoodian P, Amirian M, Zangeneh M, Jadcareh F. Seropositivity for Listeria monocytogenes in women with spontaneous abortion: a case-control study in Iran. Taiwan J Obstet Gynecol. 2009;48(1):46- 8. doi: 10.1016/s1028-4559(09)60034-6.
    26. Saeedi M, Bakhshandeh Nosrat S, Moradi A, Hedayat Mofidi SM, Behnampoor N. Comparative study of cytomegalovirus, Listeria monocytogen and Toxoplasma gondii infections in successful and non-successful pregnancy in Gorgan. Med Lab J. 2009;3(1):25-30. [Persian].
    27. Shayan R, Sattari M, Forouzandeh M. Isolation and identification of Listeria monocytogenes in vaginal samples by PCR. Pathobiology Research. 2009;12(1):51-8. [Persian].
    28. Tahery Y, Kafilzadeh F, Abolfathi Momtaz Y. Listeria monocytogenesis and abortion: a case study of pregnant women in Iran. Afr J Microbiol Res. 2009;3(11):826-32. doi: 10.5897/ajmr.9000475.
    29. Jahangiri Sisakht A, Kargar M, Mirzaee A, Aramesh SH, Akbartabar M, Mohamadkhani N, et al. Comparison the standard culture method and polymerase chain reaction in diagnosis of Listeria monocytogenes in pregnant women. Armaghane Danesh. 2012;17(2):156-63. [Persian].
    30. Eslami G, Goudarzi H, Ohadi E, Taherpour A, Pourkaveh B, Taheri S. Identification of Listeria monocytogenes virulence factors in women with abortion by polymerase chain reaction. Arch Clin Infect Dis. 2014;9(3):e19931. doi: 10.5812/ archcid.19931.
    31. Haghroosta A, Farajzadeh Sheikh A, Moosavi Shooshtari M. Investigation on the seroprevalence of Listeria monocytogenes in women with spontaneous abortion. Comp Clin Path. 2015;24(1):153-6. doi: 10.1007/s00580-013-1876-4.
    32. Sobhani Lari M, Shahrokhi N, Kargar M. A fast and easy detection for Listeria monocytogenes in urine of women using polymerase chain reaction and fluorescent probes hlyA gene. Journal of Microbial World. 2014;7(3):214-24.
    33. Eslami G, Samadi R, Taherpor A. Frequency of Listeria monocytogenes prfA, actA, inlB genes among infertile women referred to medical center of university by PCR method in 2013. New Cellular and Molecular Biotechnology Journal. 2015 Apr 10;5(18):95-9. [Persian].
    34. Seify SN, Ghaznavi Rad E, Zamani A, Alikhani MY, Rafiei M, Zand S, et al. Studying the prevalence of Listeria monocytogenes in pregnant women in Arak. J Arak Uni Med Sci. 2016;18(12):44-50. [Persian].
    35. Pourkaveh B, Ahmadi M, Eslami G, Gachkar L. Factors contributes to spontaneous abortion caused by Listeria monocytogenes, in Tehran, Iran, 2015. Cell Mol Biol (Noisyle- grand). 2016;62(9):3-10. doi: 10.14715/cmb/2016.62.9.2.
    36. Tajedini E, Talebi S, Vandyousefi J. Evaluation and comparison of ELISA and indirect immunofluorescence methods for the detection of anti-Listeria antibodies among women with spontaneous abortion referred to Kamali hospital in Karaj, Iran. Iran J Med Microbiol. 2017;11(5):98-106. [Persian].
    37. Heidarzadeh S, Soltan Dallal MM, Pourmand MR, Pirjani R, Rahimi Foroushani A, Noori M, et al. Prevalence, antimicrobial susceptibility, serotyping and virulence genes screening of Listeria monocytogenes strains at a tertiary care hospital in Tehran, Iran. Iran J Microbiol. 2018;10(5):307-13.
    38. Heidari S, Soltan Dallal MM. Prevalence of Listeria monocytogenes isolated from pregnant women with and without history of abortion and detection of hemolysin (hlyA) gene in clinical samples. Sci J Kurdistan Univ Med Sci. 2018;23(5):96-107. doi: 10.52547/sjku.23.5.96. [Persian].
    39. Zahirnia Z, Mansouri S, Saffari F. Pregnancy-related listeriosis: frequency and genotypic characteristics of L. monocytogenes from human specimens in Kerman, Iran. Wien Med Wochenschr. 2019;169(9-10):226-31. doi: 10.1007/s10354- 018-0648-9.
    40. Rezaei M, Kazemipour N, Vandyousefi J, Rokhbakhshzamin F, Irajian G. Determination of dominant serovars and molecular analysis of hly and iap genes related to Listeria monocytogenes strains isolated from spontaneous human abortions in Tehran. Iran J Med Microbiol. 2019;13(2):102-13. doi: 10.30699/ ijmm.13.2.102. [Persian].
    41. Janakiraman V. Listeriosis in pregnancy: diagnosis, treatment, and prevention. Rev Obstet Gynecol. 2008;1(4):179-85.
    42. Goulet V, Hebert M, Hedberg C, Laurent E, Vaillant V, De Valk H, et al. Incidence of listeriosis and related mortality among groups at risk of acquiring listeriosis. Clin Infect Dis. 2012;54(5):652-60. doi: 10.1093/cid/cir902.
    43. Jackson KA, Iwamoto M, Swerdlow D. Pregnancy-associated listeriosis. Epidemiol Infect. 2010;138(10):1503-9. doi: 10.1017/s0950268810000294.
    44. Nolla-Salas J, Bosch J, Gasser I, Vinas L, de Simon M, Almela M, et al. Perinatal listeriosis: a population-based multicenter study in Barcelona, Spain (1990-1996). Am J Perinatol. 1998;15(8):461-7. doi: 10.1055/s-2007-994067.
    45. Koch J, Stark K. Significant increase of listeriosis in Germanyepidemiological patterns 2001-2005. Eurosurveillance. 2006;11(6):7-8. doi: 10.2807/esm.11.06.00631-en.
    46. Mammina C, Parisi A, Guaita A, Aleo A, Bonura C, Nastasi A, et al. Enhanced surveillance of invasive listeriosis in the Lombardy region, Italy, in the years 2006-2010 reveals major clones and an increase in serotype 1/2a. BMC Infect Dis. 2013;13:152. doi: 10.1186/1471-2334-13-152.
    47. Kasper S, Huhulescu S, Auer B, Heller I, Karner F, Würzner R, et al. Epidemiology of listeriosis in Austria. Wien Klin Wochenschr. 2009;121(3-4):113-9. doi: 10.1007/s00508- 008-1130-2.
    48. Fan Z, Xie J, Li Y, Wang H. Listeriosis in mainland China: a systematic review. Int J Infect Dis. 2019;81:17-24. doi: 10.1016/j.ijid.2019.01.007.
    49. Jeffs E, Williman J, Brunton C, Gullam J, Walls T. The epidemiology of listeriosis in pregnant women and children in New Zealand from 1997 to 2016: an observational study. BMC Public Health. 2020;20(1):116. doi: 10.1186/s12889- 020-8221-z.
    50. Najafi A, Qorbanalizadgan M, Tavakoli H, Ahmadi A. Rapid diagnosis of Listeria monocytogenesby PCR method with hlyA gene. Iran J Med Microbiol. 2009;3(2):9-14. [Persian].
    51. Rodríguez-Lázaro D, Hernández M, Scortti M, Esteve T, Vázquez-Boland JA, Pla M. Quantitative detection of Listeria monocytogenes and Listeria innocua by real-time PCR: assessment of hly, iap, and lin02483 targets and AmpliFluor technology. Appl Environ Microbiol. 2004;70(3):1366-77. doi: 10.1128/aem.70.3.1366-1377.2004.
    52. Churchill RL, Lee H, Hall JC. Detection of Listeria monocytogenes and the toxin listeriolysin O in food. J Microbiol Methods. 2006;64(2):141-70. doi: 10.1016/j. mimet.2005.10.007.
    1. Milenbachs Lukowiak A, Mueller KJ, Freitag NE, Youngman P. Deregulation of Listeria monocytogenes virulence gene expression by two distinct and semi-independent pathways. Microbiology (Reading). 2004;150(Pt 2):321-33. doi: 10.1099/ mic.0.26718-0.
    2. Chen JQ, Healey S, Regan P, Laksanalamai P, Hu Z. PCRbased methodologies for detection and characterization of Listeria monocytogenes and Listeria ivanovii in foods and environmental sources. Food Sci Hum Wellness. 2017;6(2):39- 59. doi: 10.1016/j.fshw.2017.03.001.
    3. Day JB, Basavanna U. Real-time PCR detection of Listeria monocytogenes in infant formula and lettuce following macrophage-based isolation and enrichment. J Appl Microbiol. 2015;118(1):233-44. doi: 10.1111/jam.12674.
    4. Jadhav S, Bhave M, Palombo EA. Methods used for the detection and subtyping of Listeria monocytogenes. J Microbiol Methods. 2012;88(3):327-41. doi: 10.1016/j. mimet.2012.01.002.
    5. Law JW, Ab Mutalib NS, Chan KG, Lee LH. An insight into the isolation, enumeration, and molecular detection of Listeria monocytogenes in food. Front Microbiol. 2015;6:1227. doi: 10.3389/fmicb.2015.01227.
    6. Jalali M, Abedi D. Prevalence of Listeria species in food products in Isfahan, Iran. Int J Food Microbiol. 2008;122(3):336-40. doi: 10.1016/j.ijfoodmicro.2007.11.082.

     

Journal of Kerman University of Medical Sciences
Volume 32
Pages 1-8

Home

Editorial Board

Guide for Authors

Submit Manuscript

Guide for Reviewers

Contact Us