Journal of Kerman University of Medical Sciences

Study Amniotic Fluid Disorders in pregnant mothers with COVID-19 in Ardabil, Iran

Document Type : Original Article

Authors

Shahla Farzipour 1
Faranak Jalilvand 1
Firouz Amani 2
Zahra Rezazadeh 1

1 Department of Obstetrics and Gynecology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

2 Department of Community Medicine and Biostatistics, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

https://doi.org/10.34172/jkmu.3770
Abstract
Background: Pregnant individuals are considered a high-risk group for COVID-19, which has been linked to an elevated likelihood of adverse pregnancy outcomes. Nonetheless, the specific effect of SARS-CoV-2 infection on amniotic fluid volume is not fully understood. This study aimed to determine the incidence of amniotic fluid disorders (AFD) in pregnant women with COVID-19.
Methods: This cross-sectional analysis included 207 pregnant women diagnosed with COVID-19 at Alavi Hospital in Ardabil, Iran. Data were collected through patient interviews, physical assessments, medical records, and laboratory findings using a standardized checklist. Statistical analyses were conducted with SPSS software (version 25), considering a p-value below 0.05 as statistically significant.
Results: The mean age of participants was 28.3 ± 6.5 years. Among the cohort, 19 women (9.2%) with COVID-19 were diagnosed with an amniotic fluid disorder, with all cases identified as oligohydramnios. The occurrence of oligohydramnios showed significant associations with several factors: the trimester of COVID-19 infection (P=0.007), presence of dyspnea (P=0.004), extent of pulmonary involvement on imaging (P=0.027), overall disease severity (P=0.001), requirement for specific hospitalization wards (e.g., ICU) (P=0.001), delivery via cesarean section (P=0.021), and preterm birth (P=0.001).
Conclusion: The findings indicate a significantly higher incidence of oligohydramnios in women infected with COVID-19 during the third trimester, particularly among those exhibiting dyspnea and pulmonary involvement. Furthermore, oligohydramnios was significantly correlated with increased rates of cesarean delivery and preterm birth.

Highlights

Faranak Jalilvand (Google Scholar) (PubMed)

Keywords

Pregnancy
COVID-19
Amniotic fluid
Oligohydramnios
Perinatal outcomes
Subjects
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Journal of Kerman University of Medical Sciences
Volume 32
Pages 1-6

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