Journal of Kerman University of Medical Sciences

A Rare Presentation of Rapidly Growing Adenoid Cystic Carcinoma of the Floor of the Mouth in a Male

Articles in Press

Document Type : Case Report

Authors

Mahdiyeh Zarei 1
Maryam koopaie 2
Nazanin Mahdavi 3

1 Oral Medicine Department , School of Dentistry,Tehran University of Medical Sciences,Tehran,Iran

2 Oral Medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

3 Oral and maxillofacial Pathology Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Abstract
Background: Adenoid cystic carcinoma (ACC) is a rare malignancy of the oral cavity, typically characterized by a slow-growing course, a predilection for the female gender, and frequent involvement of the parotid gland.In this report, we present an unusual case of a rapidly growing and painless lesion on the floor of the mouth in a male patient Clinically, the lesion exhibited features resembling an epithelial tumor, which, along with the patient’s history of cigarette and smokeless tobacco use, posed a diagnostic challenge. Histopathological evaluation confirmed the diagnosis of Adenoid cystic carcinoma (ACC) with lymph node involvement.
Case presentation: A 55-year-old man with a history of cigarette and smokless tobacco use , had a swelling of the left oral floor and neck from 2 weeks ago, and it bled three days ago. There was a firm exophytic mass with ulcerative surface on the floor of the mouth on the left side. Submandibular lymph nodes were enlarged, hard, and fixed. He underwent an operation, and the final patholiogy report confimed ACC involvement.
Conclusion: ACC may manifest without common manifestations, and physicians should be aware.

Keywords

Adenoid cystic carcinoma
Major salivary gland
Floor of the mouth
Lymph node metastasis
Subjects
Journal of Kerman University of Medical Sciences

Articles in Press, Accepted Manuscript
Available Online from 01 August 2026

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